1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

C109H131ClF3N19O7 — CID 158094818

IUPAC1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
SMILESCC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(Cl)cccc12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(F)cccc12.COc1ccn2c(C(C)(C)NC(=O)C3[C@H]4CNC[C@@H]34)nc(C)c2c1.Cc1cc(F)cn2c(C(C)(C)CC(=O)C3[C@H]4CNC[C@@H]34)ncc12.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(F)c2n1.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12
InChIInChI=1S/C19H22FN3O.C18H20ClN3O.C18H22FN3O.C18H20FN3O.C18H24N4O2.C18H23N3O/c1-10-22-17-11(5-4-6-14(17)20)18(23-10)19(2,3)7-15(24)16-12-8-21-9-13(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-10-4-11(19)9-22-14(10)8-21-17(22)18(2,3)5-15(23)16-12-6-20-7-13(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-10-14-7-11(24-4)5-6-22(14)17(20-10)18(2,3)21-16(23)15-12-8-19-9-13(12)15;1-11-20-17(14-6-4-5-7-21(11)14)18(2,3)8-15(22)16-12-9-19-10-13(12)16/h4-6,12-13,16,21H,7-9H2,1-3H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;4,8-9,12-13,16,20H,5-7H2,1-3H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;5-7,12-13,15,19H,8-9H2,1-4H3,(H,21,23);4-7,12-13,16,19H,8-10H2,1-3H3/t12-,13+,16?;11-,12+,15?;12-,13+,16?;11-,12+,15?;12-,13+,15?;12-,13+,16?
InChIKeyFONQVWQJUMOBAX-IZLKOFADSA-N
MW1911.82 g/mol
LogP14.53
Rot. Bonds24

About 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (PubChem CID 158094818) has the molecular formula C109H131ClF3N19O7 and a molecular weight of 1911.82 g/mol. Its IUPAC name is 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.

Molecular Properties

Compound Name1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
PubChem CID158094818
Molecular FormulaC109H131ClF3N19O7
Molecular Weight1911.82 g/mol
Exact Mass1910.01
IUPAC Name1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
SMILESCC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(Cl)cccc12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(F)cccc12.COc1ccn2c(C(C)(C)NC(=O)C3[C@H]4CNC[C@@H]34)nc(C)c2c1.Cc1cc(F)cn2c(C(C)(C)CC(=O)C3[C@H]4CNC[C@@H]34)ncc12.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(F)c2n1.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12
InChIInChI=1S/C19H22FN3O.C18H20ClN3O.C18H22FN3O.C18H20FN3O.C18H24N4O2.C18H23N3O/c1-10-22-17-11(5-4-6-14(17)20)18(23-10)19(2,3)7-15(24)16-12-8-21-9-13(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-10-4-11(19)9-22-14(10)8-21-17(22)18(2,3)5-15(23)16-12-6-20-7-13(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-10-14-7-11(24-4)5-6-22(14)17(20-10)18(2,3)21-16(23)15-12-8-19-9-13(12)15;1-11-20-17(14-6-4-5-7-21(11)14)18(2,3)8-15(22)16-12-9-19-10-13(12)16/h4-6,12-13,16,21H,7-9H2,1-3H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;4,8-9,12-13,16,20H,5-7H2,1-3H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;5-7,12-13,15,19H,8-9H2,1-4H3,(H,21,23);4-7,12-13,16,19H,8-10H2,1-3H3/t12-,13+,16?;11-,12+,15?;12-,13+,16?;11-,12+,15?;12-,13+,15?;12-,13+,16?
InChIKeyFONQVWQJUMOBAX-IZLKOFADSA-N
XLogP14.53
TPSA325.10 Ų
H-Bond Donors7
H-Bond Acceptors25
Rotatable Bonds24
Heavy Atoms139
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001911.82
LogP ≤ 514.53
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1025

Analyze 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylquinazolin-4-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[2-(trifluoromethyl)quinazolin-4-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclobutyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159177995
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159674882
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;(1R,5S)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159830262
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-methoxyimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylquinazolin-4-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[2-(trifluoromethyl)quinazolin-4-yl]butan-1-one;(1S,5R)-N-[2-(5-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclobutyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159841028
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(1-cyclopropyl-8-fluoroimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(8-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;(1S,5R)-N-[2-(8-fluoro-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161125514
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2-cyclopropylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-methoxyimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;(1R,5S)-N-[2-(2,7-dimethyl-1,6-naphthyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(5-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161193496
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one
CID 162095937
3-(8-chloroimidazo[1,5-a]pyridin-3-yl)-3-methyl-1-(1,4-oxazepan-6-yl)butan-1-one;N-[2-(6,8-dimethylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-1,4-oxazepane-6-carboxamide;3-(2,8-dimethylquinazolin-4-yl)-3-methyl-1-[(2S)-morpholin-2-yl]butan-1-one;N-[2-(8-fluoro-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-1,4-oxazepane-6-carboxamide;N-[2-(8-methoxyimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-1,4-oxazepane-6-carboxamide;N-[2-(8-methyl-7,8-dihydroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-1,4-oxazepane-6-carboxamide;(2S)-N-[3-(8-methylimidazo[1,5-a]pyridin-3-yl)oxolan-3-yl]morpholine-2-carboxamide;N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-1,4-oxazepane-7-carboxamide;(2S)-N-[4-methyl-2-(8-methylimidazo[1,5-a]pyridin-3-yl)pentan-2-yl]morpholine-2-carboxamide
CID 157225996
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;(1S,5R)-N-[2-(8-fluoro-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[(1S)-1-(8-methylimidazo[1,5-a]pyridin-3-yl)ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 158721218
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-cyclopropyl-3-(8-methylimidazo[1,5-a]pyridin-3-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(4,6-dimethyl-3-pyridinyl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(8-methylindolizin-3-yl)butan-1-one;(1S,5R)-N-[2-(3,4-dihydro-2H-chromen-4-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;methane;(1S,5R)-N-[4-(8-methylimidazo[1,5-a]pyridin-3-yl)oxan-4-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 158766221
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-cyclopropyl-3-(8-methylimidazo[1,5-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(8-methylindolizin-3-yl)butan-1-one;(1R,5S)-N-[2-(3,4-dihydro-2H-chromen-4-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159476313
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(1-cyclopropyl-8-fluoroimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(8-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;(1R,5S)-N-[2-(8-fluoro-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161268001

Frequently Asked Questions

What is the IUPAC name of 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The IUPAC name of 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (CID 158094818) is 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.
What is the SMILES notation for 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The canonical SMILES for 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(Cl)cccc12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(F)cccc12.COc1ccn2c(C(C)(C)NC(=O)C3[C@H]4CNC[C@@H]34)nc(C)c2c1.Cc1cc(F)cn2c(C(C)(C)CC(=O)C3[C@H]4CNC[C@@H]34)ncc12.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(F)c2n1.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12.
What is the InChIKey of 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The InChIKey is FONQVWQJUMOBAX-IZLKOFADSA-N. The full InChI is InChI=1S/C19H22FN3O.C18H20ClN3O.C18H22FN3O.C18H20FN3O.C18H24N4O2.C18H23N3O/c1-10-22-17-11(5-4-6-14(17)20)18(23-10)19(2,3)7-15(24)16-12-8-21-9-13(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-10-4-11(19)9-22-14(10)8-21-17(22)18(2,3)5-15(23)16-12-6-20-7-13(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-10-14-7-11(24-4)5-6-22(14)17(20-10)18(2,3)21-16(23)15-12-8-19-9-13(12)15;1-11-20-17(14-6-4-5-7-21(11)14)18(2,3)8-15(22)16-12-9-19-10-13(12)16/h4-6,12-13,16,21H,7-9H2,1-3H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;4,8-9,12-13,16,20H,5-7H2,1-3H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;5-7,12-13,15,19H,8-9H2,1-4H3,(H,21,23);4-7,12-13,16,19H,8-10H2,1-3H3/t12-,13+,16?;11-,12+,15?;12-,13+,16?;11-,12+,15?;12-,13+,15?;12-,13+,16?.
What are the key properties of 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide has a molecular weight of 1911.82 g/mol, XLogP of 14.53, 24 rotatable bonds, 7 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-chloroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(6-fluoro-8-methylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoro-2-methylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;(1S,5R)-N-[2-(7-methoxy-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is sourced from PubChem (CID 158094818), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).