5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide

C103H96F2N20O13 — CID 158104743

About 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide

5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide (PubChem CID 158104743) has the molecular formula C103H96F2N20O13 and a molecular weight of 1860.02 g/mol. Its IUPAC name is 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide.

Molecular Properties

• Compound Name: 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
• PubChem CID: 158104743
• Molecular Formula: C103H96F2N20O13
• Molecular Weight: 1860.02 g/mol
• Exact Mass: 1858.74
• IUPAC Name: 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
• SMILES: O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)CC4)c3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(N4CCCC4)c3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(N4CCCCC4)c3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(N4CCOCC4)c3)cc12
• InChI: InChI=1S/C27H25F2N5O3.C26H25N5O3.C25H23N5O4.C25H23N5O3/c28-27(29)5-7-34(8-6-27)16-17-11-19(15-30-14-17)18-1-3-22-21(12-18)25(33-32-22)26(35)31-20-2-4-23-24(13-20)37-10-9-36-23;32-26(28-19-5-7-23-24(14-19)34-11-10-33-23)25-21-13-17(4-6-22(21)29-30-25)18-12-20(16-27-15-18)31-8-2-1-3-9-31;31-25(27-18-2-4-22-23(13-18)34-10-9-33-22)24-20-12-16(1-3-21(20)28-29-24)17-11-19(15-26-14-17)30-5-7-32-8-6-30;31-25(27-18-4-6-22-23(13-18)33-10-9-32-22)24-20-12-16(3-5-21(20)28-29-24)17-11-19(15-26-14-17)30-7-1-2-8-30/h1-4,11-15H,5-10,16H2,(H,31,35)(H,32,33);4-7,12-16H,1-3,8-11H2,(H,28,32)(H,29,30);1-4,11-15H,5-10H2,(H,27,31)(H,28,29);3-6,11-15H,1-2,7-10H2,(H,27,31)(H,28,29)
• InChIKey: FPRUQZPFEAZTGP-UHFFFAOYSA-N
• XLogP: 17.25
• TPSA: 378.71 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 25
• Rotatable Bonds: 17
• Heavy Atoms: 138
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1860.02
LogP ≤ 5	17.25
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

The IUPAC name of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide (CID 158104743) is 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide.

What is the SMILES notation for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

The canonical SMILES for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide is O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)CC4)c3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(N4CCCC4)c3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(N4CCCCC4)c3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(N4CCOCC4)c3)cc12.

What is the InChIKey of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

The InChIKey is FPRUQZPFEAZTGP-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H25F2N5O3.C26H25N5O3.C25H23N5O4.C25H23N5O3/c28-27(29)5-7-34(8-6-27)16-17-11-19(15-30-14-17)18-1-3-22-21(12-18)25(33-32-22)26(35)31-20-2-4-23-24(13-20)37-10-9-36-23;32-26(28-19-5-7-23-24(14-19)34-11-10-33-23)25-21-13-17(4-6-22(21)29-30-25)18-12-20(16-27-15-18)31-8-2-1-3-9-31;31-25(27-18-2-4-22-23(13-18)34-10-9-33-22)24-20-12-16(1-3-21(20)28-29-24)17-11-19(15-26-14-17)30-5-7-32-8-6-30;31-25(27-18-4-6-22-23(13-18)33-10-9-32-22)24-20-12-16(3-5-21(20)28-29-24)17-11-19(15-26-14-17)30-7-1-2-8-30/h1-4,11-15H,5-10,16H2,(H,31,35)(H,32,33);4-7,12-16H,1-3,8-11H2,(H,28,32)(H,29,30);1-4,11-15H,5-10H2,(H,27,31)(H,28,29);3-6,11-15H,1-2,7-10H2,(H,27,31)(H,28,29).

What are the key properties of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide has a molecular weight of 1860.02 g/mol, XLogP of 17.25, 17 rotatable bonds, 8 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-morpholin-4-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide is sourced from PubChem (CID 158104743), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).