2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide

C225H221N47O16S8 — CID 158110418

IUPAC2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide
SMILESCN1CCc2ccc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4cccc(C#N)c4)c3)cc2C1.CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4ccc(C#N)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4ccccc4C#N)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4cc(-c5ccncc5)n[nH]4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4ccc(-n5ccnc5)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4cccc(-c5ccncc5)c4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4csc(-c5ccncc5)n4)c3)sc2C1.N#Cc1ccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CN(Cc3ccccc3)CC4)c2)cc1
InChIInChI=1S/C32H30N6O2S.C30H29N5O2S.C29H29N5O2.C28H28N6O2S.C27H27N7O2S.C27H26N6O2S2.2C26H26N6O2S/c33-19-22-11-13-26(14-12-22)34-32(40)38-16-5-10-28(38)24-8-4-9-25(18-24)30(39)36-31-35-27-15-17-37(21-29(27)41-31)20-23-6-2-1-3-7-23;1-34-16-12-25-27(19-34)38-30(32-25)33-28(36)23-7-3-6-22(18-23)26-9-4-15-35(26)29(37)24-8-2-5-21(17-24)20-10-13-31-14-11-20;1-33-14-12-21-10-11-26(17-24(21)19-33)31-28(35)23-7-3-6-22(16-23)27-9-4-13-34(27)29(36)32-25-8-2-5-20(15-25)18-30;1-32-14-11-23-25(17-32)37-28(30-23)31-26(35)21-5-2-4-20(16-21)24-6-3-13-34(24)27(36)19-7-9-22(10-8-19)33-15-12-29-18-33;1-33-13-9-20-24(16-33)37-27(29-20)30-25(35)19-5-2-4-18(14-19)23-6-3-12-34(23)26(36)22-15-21(31-32-22)17-7-10-28-11-8-17;1-32-13-9-20-23(15-32)37-27(30-20)31-24(34)19-5-2-4-18(14-19)22-6-3-12-33(22)26(35)21-16-36-25(29-21)17-7-10-28-11-8-17;1-31-13-11-21-23(16-31)35-25(29-21)30-24(33)19-5-2-4-18(14-19)22-6-3-12-32(22)26(34)28-20-9-7-17(15-27)8-10-20;1-31-13-11-21-23(16-31)35-25(28-21)30-24(33)18-8-4-7-17(14-18)22-10-5-12-32(22)26(34)29-20-9-3-2-6-19(20)15-27/h1-4,6-9,11-14,18,28H,5,10,15-17,20-21H2,(H,34,40)(H,35,36,39);2-3,5-8,10-11,13-14,17-18,26H,4,9,12,15-16,19H2,1H3,(H,32,33,36);2-3,5-8,10-11,15-17,27H,4,9,12-14,19H2,1H3,(H,31,35)(H,32,36);2,4-5,7-10,12,15-16,18,24H,3,6,11,13-14,17H2,1H3,(H,30,31,35);2,4-5,7-8,10-11,14-15,23H,3,6,9,12-13,16H2,1H3,(H,31,32)(H,29,30,35);2,4-5,7-8,10-11,14,16,22H,3,6,9,12-13,15H2,1H3,(H,30,31,34);2,4-5,7-10,14,22H,3,6,11-13,16H2,1H3,(H,28,34)(H,29,30,33);2-4,6-9,14,22H,5,10-13,16H2,1H3,(H,29,34)(H,28,30,33)/t;26-;;24-;23-;22-;;/m.1.111../s1
InChIKeyFQJAVAZEAWDKOF-AKKSPPSISA-N
MW4096.09 g/mol
LogP39.60
Rot. Bonds38

About 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide

2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide (PubChem CID 158110418) has the molecular formula C225H221N47O16S8 and a molecular weight of 4096.09 g/mol. Its IUPAC name is 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide.

Molecular Properties

Compound Name2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide
PubChem CID158110418
Molecular FormulaC225H221N47O16S8
Molecular Weight4096.09 g/mol
Exact Mass4092.57
IUPAC Name2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide
SMILESCN1CCc2ccc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4cccc(C#N)c4)c3)cc2C1.CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4ccc(C#N)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4ccccc4C#N)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4cc(-c5ccncc5)n[nH]4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4ccc(-n5ccnc5)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4cccc(-c5ccncc5)c4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4csc(-c5ccncc5)n4)c3)sc2C1.N#Cc1ccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CN(Cc3ccccc3)CC4)c2)cc1
InChIInChI=1S/C32H30N6O2S.C30H29N5O2S.C29H29N5O2.C28H28N6O2S.C27H27N7O2S.C27H26N6O2S2.2C26H26N6O2S/c33-19-22-11-13-26(14-12-22)34-32(40)38-16-5-10-28(38)24-8-4-9-25(18-24)30(39)36-31-35-27-15-17-37(21-29(27)41-31)20-23-6-2-1-3-7-23;1-34-16-12-25-27(19-34)38-30(32-25)33-28(36)23-7-3-6-22(18-23)26-9-4-15-35(26)29(37)24-8-2-5-21(17-24)20-10-13-31-14-11-20;1-33-14-12-21-10-11-26(17-24(21)19-33)31-28(35)23-7-3-6-22(16-23)27-9-4-13-34(27)29(36)32-25-8-2-5-20(15-25)18-30;1-32-14-11-23-25(17-32)37-28(30-23)31-26(35)21-5-2-4-20(16-21)24-6-3-13-34(24)27(36)19-7-9-22(10-8-19)33-15-12-29-18-33;1-33-13-9-20-24(16-33)37-27(29-20)30-25(35)19-5-2-4-18(14-19)23-6-3-12-34(23)26(36)22-15-21(31-32-22)17-7-10-28-11-8-17;1-32-13-9-20-23(15-32)37-27(30-20)31-24(34)19-5-2-4-18(14-19)22-6-3-12-33(22)26(35)21-16-36-25(29-21)17-7-10-28-11-8-17;1-31-13-11-21-23(16-31)35-25(29-21)30-24(33)19-5-2-4-18(14-19)22-6-3-12-32(22)26(34)28-20-9-7-17(15-27)8-10-20;1-31-13-11-21-23(16-31)35-25(28-21)30-24(33)18-8-4-7-17(14-18)22-10-5-12-32(22)26(34)29-20-9-3-2-6-19(20)15-27/h1-4,6-9,11-14,18,28H,5,10,15-17,20-21H2,(H,34,40)(H,35,36,39);2-3,5-8,10-11,13-14,17-18,26H,4,9,12,15-16,19H2,1H3,(H,32,33,36);2-3,5-8,10-11,15-17,27H,4,9,12-14,19H2,1H3,(H,31,35)(H,32,36);2,4-5,7-10,12,15-16,18,24H,3,6,11,13-14,17H2,1H3,(H,30,31,35);2,4-5,7-8,10-11,14-15,23H,3,6,9,12-13,16H2,1H3,(H,31,32)(H,29,30,35);2,4-5,7-8,10-11,14,16,22H,3,6,9,12-13,15H2,1H3,(H,30,31,34);2,4-5,7-10,14,22H,3,6,11-13,16H2,1H3,(H,28,34)(H,29,30,33);2-4,6-9,14,22H,5,10-13,16H2,1H3,(H,29,34)(H,28,30,33)/t;26-;;24-;23-;22-;;/m.1.111../s1
InChIKeyFQJAVAZEAWDKOF-AKKSPPSISA-N
XLogP39.60
TPSA752.77 Ų
H-Bond Donors13
H-Bond Acceptors50
Rotatable Bonds38
Heavy Atoms296
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004096.09
LogP ≤ 539.60
H-Bond Donors ≤ 513
H-Bond Acceptors ≤ 1050

Analyze 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide with MolForge

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Related Compounds

2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(3-cyanophenyl)pyrrolidine-1-carboxamide
CID 56597901
(2R)-2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(3-cyanophenyl)pyrrolidine-1-carboxamide
CID 88591178
(2S)-N-(3-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide
CID 56598843
N-(2-aminophenyl)-2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide
CID 88561710
N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-3-ylbenzoyl)pyrrolidin-2-yl]benzamide
CID 56597900
N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(4-pyridin-3-ylbenzoyl)pyrrolidin-2-yl]benzamide
CID 56598577
N-(3-aminophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide
CID 88561509
N-[(6S)-6-(propylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide
CID 88561634
N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-[4-(thiadiazol-4-yl)benzoyl]pyrrolidin-2-yl]benzamide
CID 56598445
N-(3-cyanophenyl)-2-[3-[(6-ethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide
CID 123451481
2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-[4-[(methylideneamino)methyl]phenyl]pyrrolidine-1-carboxamide
CID 123578067
N-(4-cyanophenyl)-3-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]piperidine-1-carboxamide
CID 88561615

Frequently Asked Questions

What is the IUPAC name of 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide?
The IUPAC name of 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide (CID 158110418) is 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide.
What is the SMILES notation for 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide?
The canonical SMILES for 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide is CN1CCc2ccc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4cccc(C#N)c4)c3)cc2C1.CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4ccc(C#N)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4ccccc4C#N)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4cc(-c5ccncc5)n[nH]4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4ccc(-n5ccnc5)cc4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4cccc(-c5ccncc5)c4)c3)sc2C1.CN1CCc2nc(NC(=O)c3cccc([C@H]4CCCN4C(=O)c4csc(-c5ccncc5)n4)c3)sc2C1.N#Cc1ccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CN(Cc3ccccc3)CC4)c2)cc1.
What is the InChIKey of 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide?
The InChIKey is FQJAVAZEAWDKOF-AKKSPPSISA-N. The full InChI is InChI=1S/C32H30N6O2S.C30H29N5O2S.C29H29N5O2.C28H28N6O2S.C27H27N7O2S.C27H26N6O2S2.2C26H26N6O2S/c33-19-22-11-13-26(14-12-22)34-32(40)38-16-5-10-28(38)24-8-4-9-25(18-24)30(39)36-31-35-27-15-17-37(21-29(27)41-31)20-23-6-2-1-3-7-23;1-34-16-12-25-27(19-34)38-30(32-25)33-28(36)23-7-3-6-22(18-23)26-9-4-15-35(26)29(37)24-8-2-5-21(17-24)20-10-13-31-14-11-20;1-33-14-12-21-10-11-26(17-24(21)19-33)31-28(35)23-7-3-6-22(16-23)27-9-4-13-34(27)29(36)32-25-8-2-5-20(15-25)18-30;1-32-14-11-23-25(17-32)37-28(30-23)31-26(35)21-5-2-4-20(16-21)24-6-3-13-34(24)27(36)19-7-9-22(10-8-19)33-15-12-29-18-33;1-33-13-9-20-24(16-33)37-27(29-20)30-25(35)19-5-2-4-18(14-19)23-6-3-12-34(23)26(36)22-15-21(31-32-22)17-7-10-28-11-8-17;1-32-13-9-20-23(15-32)37-27(30-20)31-24(34)19-5-2-4-18(14-19)22-6-3-12-33(22)26(35)21-16-36-25(29-21)17-7-10-28-11-8-17;1-31-13-11-21-23(16-31)35-25(29-21)30-24(33)19-5-2-4-18(14-19)22-6-3-12-32(22)26(34)28-20-9-7-17(15-27)8-10-20;1-31-13-11-21-23(16-31)35-25(28-21)30-24(33)18-8-4-7-17(14-18)22-10-5-12-32(22)26(34)29-20-9-3-2-6-19(20)15-27/h1-4,6-9,11-14,18,28H,5,10,15-17,20-21H2,(H,34,40)(H,35,36,39);2-3,5-8,10-11,13-14,17-18,26H,4,9,12,15-16,19H2,1H3,(H,32,33,36);2-3,5-8,10-11,15-17,27H,4,9,12-14,19H2,1H3,(H,31,35)(H,32,36);2,4-5,7-10,12,15-16,18,24H,3,6,11,13-14,17H2,1H3,(H,30,31,35);2,4-5,7-8,10-11,14-15,23H,3,6,9,12-13,16H2,1H3,(H,31,32)(H,29,30,35);2,4-5,7-8,10-11,14,16,22H,3,6,9,12-13,15H2,1H3,(H,30,31,34);2,4-5,7-10,14,22H,3,6,11-13,16H2,1H3,(H,28,34)(H,29,30,33);2-4,6-9,14,22H,5,10-13,16H2,1H3,(H,29,34)(H,28,30,33)/t;26-;;24-;23-;22-;;/m.1.111../s1.
What are the key properties of 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide?
2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide has a molecular weight of 4096.09 g/mol, XLogP of 39.60, 38 rotatable bonds, 13 hydrogen bond donors, and 50 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-[(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]-N-(4-cyanophenyl)pyrrolidine-1-carboxamide;N-(3-cyanophenyl)-2-[3-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(2-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;N-(4-cyanophenyl)-2-[3-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl]pyrrolidine-1-carboxamide;3-[(2R)-1-(4-imidazol-1-ylbenzoyl)pyrrolidin-2-yl]-N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-ylbenzoyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(3-pyridin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidin-2-yl]benzamide;N-(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)-3-[(2R)-1-(2-pyridin-4-yl-1,3-thiazole-4-carbonyl)pyrrolidin-2-yl]benzamide is sourced from PubChem (CID 158110418), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).