N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide

C91H114Cl3F7N20O9 — CID 158300782

About N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide (PubChem CID 158300782) has the molecular formula C91H114Cl3F7N20O9 and a molecular weight of 1871.39 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide
• PubChem CID: 158300782
• Molecular Formula: C91H114Cl3F7N20O9
• Molecular Weight: 1871.39 g/mol
• Exact Mass: 1868.80
• IUPAC Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide
• SMILES: CC(C)(C)CC(=O)Nc1nc2ccc(C3CC3)nc2n1CC(F)(F)F.CC(C)(C)OCCC(=O)Nc1nc2ccc(C3CC3)nc2n1CC(F)(F)F.CC1(C)CCCC(CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)O1.CC1(C)CCC[C@H](CC(=O)Nc2nc3ccc(Cl)nc3n2-c2ccc(F)cc2)O1.CCCn1c(NC(=O)CCOC(C)(C)C)nc2ccc(Cl)nc21
• InChI: InChI=1S/C21H22ClFN4O2.C19H25ClN4O2.C18H23F3N4O2.C17H21F3N4O.C16H23ClN4O2/c1-21(2)11-3-4-15(29-21)12-18(28)26-20-24-16-9-10-17(22)25-19(16)27(20)14-7-5-13(23)6-8-14;1-19(2)10-4-7-13(26-19)11-16(25)23-18-21-14-8-9-15(20)22-17(14)24(18)12-5-3-6-12;1-17(2,3)27-9-8-14(26)24-16-23-13-7-6-12(11-4-5-11)22-15(13)25(16)10-18(19,20)21;1-16(2,3)8-13(25)23-15-22-12-7-6-11(10-4-5-10)21-14(12)24(15)9-17(18,19)20;1-5-9-21-14-11(6-7-12(17)19-14)18-15(21)20-13(22)8-10-23-16(2,3)4/h5-10,15H,3-4,11-12H2,1-2H3,(H,24,26,28);8-9,12-13H,3-7,10-11H2,1-2H3,(H,21,23,25);6-7,11H,4-5,8-10H2,1-3H3,(H,23,24,26);6-7,10H,4-5,8-9H2,1-3H3,(H,22,23,25);6-7H,5,8-10H2,1-4H3,(H,18,20,22)/t15-;;;;/m1..../s1
• InChIKey: GMLXUDFBZGOLRB-FKOXPEIHSA-N
• XLogP: 21.27
• TPSA: 335.97 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 24
• Rotatable Bonds: 24
• Heavy Atoms: 130
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1871.39
LogP ≤ 5	21.27
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	24

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide?

The IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide (CID 158300782) is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide.

What is the SMILES notation for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide?

The canonical SMILES for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide is CC(C)(C)CC(=O)Nc1nc2ccc(C3CC3)nc2n1CC(F)(F)F.CC(C)(C)OCCC(=O)Nc1nc2ccc(C3CC3)nc2n1CC(F)(F)F.CC1(C)CCCC(CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)O1.CC1(C)CCC[C@H](CC(=O)Nc2nc3ccc(Cl)nc3n2-c2ccc(F)cc2)O1.CCCn1c(NC(=O)CCOC(C)(C)C)nc2ccc(Cl)nc21.

What is the InChIKey of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide?

The InChIKey is GMLXUDFBZGOLRB-FKOXPEIHSA-N. The full InChI is InChI=1S/C21H22ClFN4O2.C19H25ClN4O2.C18H23F3N4O2.C17H21F3N4O.C16H23ClN4O2/c1-21(2)11-3-4-15(29-21)12-18(28)26-20-24-16-9-10-17(22)25-19(16)27(20)14-7-5-13(23)6-8-14;1-19(2)10-4-7-13(26-19)11-16(25)23-18-21-14-8-9-15(20)22-17(14)24(18)12-5-3-6-12;1-17(2,3)27-9-8-14(26)24-16-23-13-7-6-12(11-4-5-11)22-15(13)25(16)10-18(19,20)21;1-16(2,3)8-13(25)23-15-22-12-7-6-11(10-4-5-10)21-14(12)24(15)9-17(18,19)20;1-5-9-21-14-11(6-7-12(17)19-14)18-15(21)20-13(22)8-10-23-16(2,3)4/h5-10,15H,3-4,11-12H2,1-2H3,(H,24,26,28);8-9,12-13H,3-7,10-11H2,1-2H3,(H,21,23,25);6-7,11H,4-5,8-10H2,1-3H3,(H,23,24,26);6-7,10H,4-5,8-9H2,1-3H3,(H,22,23,25);6-7H,5,8-10H2,1-4H3,(H,18,20,22)/t15-;;;;/m1..../s1.

What are the key properties of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide?

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide has a molecular weight of 1871.39 g/mol, XLogP of 21.27, 24 rotatable bonds, 5 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(6,6-dimethyloxan-2-yl)acetamide;N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-2-[(2R)-6,6-dimethyloxan-2-yl]acetamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-cyclopropyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3-[(2-methylpropan-2-yl)oxy]propanamide is sourced from PubChem (CID 158300782), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).