N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

C145H135F20N29O14S6 — CID 158325458

About N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (PubChem CID 158325458) has the molecular formula C145H135F20N29O14S6 and a molecular weight of 3080.23 g/mol. Its IUPAC name is N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

Molecular Properties

• Compound Name: N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• PubChem CID: 158325458
• Molecular Formula: C145H135F20N29O14S6
• Molecular Weight: 3080.23 g/mol
• Exact Mass: 3077.87
• IUPAC Name: N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• SMILES: CCc1cc(OC)c2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCC3)c2c1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ncccn1.Cc1cc2c(cc1F)c(C#N)c(-c1cc(C)c(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccn1.Cc1cc2c(cc1F)c(C#N)c(-c1cc(C)c(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ncccn1.Cc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCCC1
• InChI: InChI=1S/C25H26F4N4O3S.C25H24F4N4O2S.C24H19F4N5O2S.C24H25F3N4O3S.C24H23FN6O2S.C23H18F4N6O2S/c1-14-11-20-17(12-18(14)26)21(23(30)34)22(33(20)15-5-3-2-4-6-15)19-8-7-16(13-31-19)37(35,36)32-24(9-10-24)25(27,28)29;1-15-11-22-18(12-20(15)26)19(13-30)23(33(22)16-5-3-2-4-6-16)21-8-7-17(14-31-21)36(34,35)32-24(9-10-24)25(27,28)29;1-13-9-20-16(10-18(13)25)17(11-29)23(33(20)22-6-4-5-7-30-22)19-8-14(2)21(12-31-19)36(34,35)32-15(3)24(26,27)28;1-4-15-10-20-22(21(11-15)34-3)18(12-28)23(31(20)16-6-5-7-16)19-9-8-17(13-29-19)35(32,33)30-14(2)24(25,26)27;1-5-15-11-21-17(12-19(15)25)18(13-26)22(31(21)23-27-9-6-10-28-23)20-8-7-16(14-29-20)34(32,33)30-24(2,3)4;1-12-8-19-15(9-17(12)24)16(10-28)21(33(19)22-29-5-4-6-30-22)18-7-13(2)20(11-31-18)36(34,35)32-14(3)23(25,26)27/h7-8,11-13,15,32H,2-6,9-10H2,1H3,(H2,30,34);7-8,11-12,14,16,32H,2-6,9-10H2,1H3;4-10,12,15,32H,1-3H3;8-11,13-14,16,30H,4-7H2,1-3H3;6-12,14,30H,5H2,1-4H3;4-9,11,14,32H,1-3H3/t;;15-;14-;;14-/m..00.0/s1
• InChIKey: GPISNKIJJYQKPQ-XDJWASCNSA-N
• XLogP: 29.55
• TPSA: 619.66 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 36
• Rotatable Bonds: 33
• Heavy Atoms: 214
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3080.23
LogP ≤ 5	29.55
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The IUPAC name of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (CID 158325458) is N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

What is the SMILES notation for N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The canonical SMILES for N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is CCc1cc(OC)c2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCC3)c2c1.CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2-c1ncccn1.Cc1cc2c(cc1F)c(C#N)c(-c1cc(C)c(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccn1.Cc1cc2c(cc1F)c(C#N)c(-c1cc(C)c(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ncccn1.Cc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCCC1.

What is the InChIKey of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The InChIKey is GPISNKIJJYQKPQ-XDJWASCNSA-N. The full InChI is InChI=1S/C25H26F4N4O3S.C25H24F4N4O2S.C24H19F4N5O2S.C24H25F3N4O3S.C24H23FN6O2S.C23H18F4N6O2S/c1-14-11-20-17(12-18(14)26)21(23(30)34)22(33(20)15-5-3-2-4-6-15)19-8-7-16(13-31-19)37(35,36)32-24(9-10-24)25(27,28)29;1-15-11-22-18(12-20(15)26)19(13-30)23(33(22)16-5-3-2-4-6-16)21-8-7-17(14-31-21)36(34,35)32-24(9-10-24)25(27,28)29;1-13-9-20-16(10-18(13)25)17(11-29)23(33(20)22-6-4-5-7-30-22)19-8-14(2)21(12-31-19)36(34,35)32-15(3)24(26,27)28;1-4-15-10-20-22(21(11-15)34-3)18(12-28)23(31(20)16-6-5-7-16)19-9-8-17(13-29-19)35(32,33)30-14(2)24(25,26)27;1-5-15-11-21-17(12-19(15)25)18(13-26)22(31(21)23-27-9-6-10-28-23)20-8-7-16(14-29-20)34(32,33)30-24(2,3)4;1-12-8-19-15(9-17(12)24)16(10-28)21(33(19)22-29-5-4-6-30-22)18-7-13(2)20(11-31-18)36(34,35)32-14(3)23(25,26)27/h7-8,11-13,15,32H,2-6,9-10H2,1H3,(H2,30,34);7-8,11-12,14,16,32H,2-6,9-10H2,1H3;4-10,12,15,32H,1-3H3;8-11,13-14,16,30H,4-7H2,1-3H3;6-12,14,30H,5H2,1-4H3;4-9,11,14,32H,1-3H3/t;;15-;14-;;14-/m..00.0/s1.

What are the key properties of N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide has a molecular weight of 3080.23 g/mol, XLogP of 29.55, 33 rotatable bonds, 7 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for N-tert-butyl-6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-ethyl-4-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-fluoro-6-methylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyridin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-fluoro-6-methyl-1-pyrimidin-2-ylindol-2-yl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is sourced from PubChem (CID 158325458), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).