N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide

C82H102N26O12S4 — CID 158343126

About N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide

N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide (PubChem CID 158343126) has the molecular formula C82H102N26O12S4 and a molecular weight of 1772.16 g/mol. Its IUPAC name is N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide.

Molecular Properties

• Compound Name: N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide
• PubChem CID: 158343126
• Molecular Formula: C82H102N26O12S4
• Molecular Weight: 1772.16 g/mol
• Exact Mass: 1770.71
• IUPAC Name: N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide
• SMILES: CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)n2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)n2)C3=O)s1
• InChI: InChI=1S/2C21H26N6O3S.2C20H25N7O3S/c2*1-12-9-16(10-13(2)23-12)27-18(29)21(25-20(27)30)5-7-26(8-6-21)14(3)17-11-22-19(31-17)24-15(4)28;2*1-11-9-16(23-13(3)22-11)27-17(29)20(25-19(27)30)5-7-26(8-6-20)12(2)15-10-21-18(31-15)24-14(4)28/h2*9-11,14H,5-8H2,1-4H3,(H,25,30)(H,22,24,28);2*9-10,12H,5-8H2,1-4H3,(H,25,30)(H,21,24,28)/t2*14-;2*12-/m1010/s1
• InChIKey: GRJYYCGDBWMMDS-BXTPOJFMSA-N
• XLogP: 9.85
• TPSA: 455.90 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 30
• Rotatable Bonds: 16
• Heavy Atoms: 124
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1772.16
LogP ≤ 5	9.85
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The IUPAC name of N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide (CID 158343126) is N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide.

What is the SMILES notation for N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The canonical SMILES for N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide is CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)n2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)c2)C3=O)s1.CC(=O)Nc1ncc([C@H](C)N2CCC3(CC2)NC(=O)N(c2cc(C)nc(C)n2)C3=O)s1.

What is the InChIKey of N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

The InChIKey is GRJYYCGDBWMMDS-BXTPOJFMSA-N. The full InChI is InChI=1S/2C21H26N6O3S.2C20H25N7O3S/c2*1-12-9-16(10-13(2)23-12)27-18(29)21(25-20(27)30)5-7-26(8-6-21)14(3)17-11-22-19(31-17)24-15(4)28;2*1-11-9-16(23-13(3)22-11)27-17(29)20(25-19(27)30)5-7-26(8-6-20)12(2)15-10-21-18(31-15)24-14(4)28/h2*9-11,14H,5-8H2,1-4H3,(H,25,30)(H,22,24,28);2*9-10,12H,5-8H2,1-4H3,(H,25,30)(H,21,24,28)/t2*14-;2*12-/m1010/s1.

What are the key properties of N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide?

N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide has a molecular weight of 1772.16 g/mol, XLogP of 9.85, 16 rotatable bonds, 8 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-[(1R)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethyl-4-pyridinyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1R)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide;N-[5-[(1S)-1-[3-(2,6-dimethylpyrimidin-4-yl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1,3-thiazol-2-yl]acetamide is sourced from PubChem (CID 158343126), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).