4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide

C153H158F16N30O23 — CID 158343634

IUPAC4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide
SMILESCc1ncc(NC(=O)c2cc(C(C)(C)C#N)ccn2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cc(C(C)(F)F)ccn2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(O)C(F)(F)F)c2)cc1-c1cnc(OC2CCOCC2)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1
InChIInChI=1S/C29H31F3N4O5.C27H30N6O4.2C25H27F2N5O4.C24H23F4N5O3.C23H20F5N5O3/c1-18-24(15-22(17-33-18)35-27(38)20-4-2-3-19(13-20)26(37)29(30,31)32)21-14-25(36-7-11-40-12-8-36)28(34-16-21)41-23-5-9-39-10-6-23;1-18-22(19-12-24(33-6-9-36-10-7-33)26(31-15-19)37-11-8-34)14-21(16-30-18)32-25(35)23-13-20(4-5-29-23)27(2,3)17-28;1-15-19(17-10-20(32-6-8-35-9-7-32)23(30-13-17)36-24(26)27)12-18(14-29-15)31-22(33)16-4-5-28-21(11-16)25(2,3)34;1-16-20(17-11-22(32-5-8-35-9-6-32)24(30-14-17)36-10-7-33)13-19(15-29-16)31-23(34)21-12-18(3-4-28-21)25(2,26)27;1-14-18(16-9-19(33-5-7-35-8-6-33)22(31-12-16)36-23(25)26)11-17(13-30-14)32-21(34)15-3-4-29-20(10-15)24(2,27)28;1-13-17(15-8-18(33-4-6-35-7-5-33)21(31-11-15)36-22(24)25)10-16(12-30-13)32-20(34)14-2-3-29-19(9-14)23(26,27)28/h2-4,13-17,23,26,37H,5-12H2,1H3,(H,35,38);4-5,12-16,34H,6-11H2,1-3H3,(H,32,35);4-5,10-14,24,34H,6-9H2,1-3H3,(H,31,33);3-4,11-15,33H,5-10H2,1-2H3,(H,31,34);3-4,9-13,23H,5-8H2,1-2H3,(H,32,34);2-3,8-12,22H,4-7H2,1H3,(H,32,34)
InChIKeyGRLOTZWUEFSPEV-UHFFFAOYSA-N
MW3089.10 g/mol
LogP24.19
Rot. Bonds43

About 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide

4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide (PubChem CID 158343634) has the molecular formula C153H158F16N30O23 and a molecular weight of 3089.10 g/mol. Its IUPAC name is 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide.

Molecular Properties

Compound Name4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide
PubChem CID158343634
Molecular FormulaC153H158F16N30O23
Molecular Weight3089.10 g/mol
Exact Mass3087.19
IUPAC Name4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide
SMILESCc1ncc(NC(=O)c2cc(C(C)(C)C#N)ccn2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cc(C(C)(F)F)ccn2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(O)C(F)(F)F)c2)cc1-c1cnc(OC2CCOCC2)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1
InChIInChI=1S/C29H31F3N4O5.C27H30N6O4.2C25H27F2N5O4.C24H23F4N5O3.C23H20F5N5O3/c1-18-24(15-22(17-33-18)35-27(38)20-4-2-3-19(13-20)26(37)29(30,31)32)21-14-25(36-7-11-40-12-8-36)28(34-16-21)41-23-5-9-39-10-6-23;1-18-22(19-12-24(33-6-9-36-10-7-33)26(31-15-19)37-11-8-34)14-21(16-30-18)32-25(35)23-13-20(4-5-29-23)27(2,3)17-28;1-15-19(17-10-20(32-6-8-35-9-7-32)23(30-13-17)36-24(26)27)12-18(14-29-15)31-22(33)16-4-5-28-21(11-16)25(2,3)34;1-16-20(17-11-22(32-5-8-35-9-6-32)24(30-14-17)36-10-7-33)13-19(15-29-16)31-23(34)21-12-18(3-4-28-21)25(2,26)27;1-14-18(16-9-19(33-5-7-35-8-6-33)22(31-12-16)36-23(25)26)11-17(13-30-14)32-21(34)15-3-4-29-20(10-15)24(2,27)28;1-13-17(15-8-18(33-4-6-35-7-5-33)21(31-11-15)36-22(24)25)10-16(12-30-13)32-20(34)14-2-3-29-19(9-14)23(26,27)28/h2-4,13-17,23,26,37H,5-12H2,1H3,(H,35,38);4-5,12-16,34H,6-11H2,1-3H3,(H,32,35);4-5,10-14,24,34H,6-9H2,1-3H3,(H,31,33);3-4,11-15,33H,5-10H2,1-2H3,(H,31,34);3-4,9-13,23H,5-8H2,1-2H3,(H,32,34);2-3,8-12,22H,4-7H2,1H3,(H,32,34)
InChIKeyGRLOTZWUEFSPEV-UHFFFAOYSA-N
XLogP24.19
TPSA637.87 Ų
H-Bond Donors10
H-Bond Acceptors47
Rotatable Bonds43
Heavy Atoms222
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003089.10
LogP ≤ 524.19
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1047

Analyze 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide with MolForge

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Launch Full Analysis

Related Compounds

N-[5-[6-[[4-[2-[1-[4-[2-(2-cyanopropan-2-yl)-5-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]-3-pyridinyl]-3-pyridinyl]morpholin-2-yl]azetidin-3-yl]oxy-5-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]-3-pyridinyl]-3-pyridinyl]morpholin-2-yl]methoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 130425796
2-(2-cyanopropan-2-yl)-N-[3-[1-(2-hydroxyethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-[1-(2-hydroxyethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-6-oxo-1H-pyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide
CID 161133218
6-(2-cyanopropan-2-yl)-N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;4-(2-cyanopropan-2-yl)-N-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]pyridine-2-carboxamide;1-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-[5-fluoro-2-(trifluoromethyl)-4-pyridinyl]ethanone;2-(2-fluoropropan-2-yl)-N-[6-methyl-5-[5-morpholin-4-yl-6-(2-oxaspiro[3.3]heptan-6-yloxy)-3-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;4-(2-hydroxypropan-2-yl)-N-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]pyridine-2-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 160879514
N-[5-[6-(1,1-dihydroxythian-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 118870900
N-[5-(6-but-3-ynoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 135390019
2-(2-cyanopropan-2-yl)-N-[3-[6-(2-methoxyethoxy)-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-(5-morpholin-4-yl-6-propan-2-yloxypyridazin-3-yl)phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[6-(2-methoxyethoxy)-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[3-[6-(2-methoxyethoxy)-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[3-[6-(2-methoxyethoxy)-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-methoxyethoxy)-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 158303011
N-[5-[6-(4-deuterio-3-fluorooxan-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 90464871
N-[6-methyl-5-[5-morpholin-4-yl-6-[(2S,4S)-2-(prop-2-ynoxymethyl)oxan-4-yl]oxy-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 135390039
N-[6-methyl-5-[6-[methyl-[[4-[5-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]-3-pyridinyl]-2-[(3S)-oxolan-3-yl]oxy-3-pyridinyl]morpholin-2-yl]methyl]amino]-5-morpholin-4-yl-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 130425556
3-(1,1-difluoroethyl)-N-[6-methyl-5-(2-morpholin-4-yl-4-pyridinyl)-3-pyridinyl]benzamide
CID 86297692
N-[5-[6-[4-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]phenoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 146502149
2-(1,1-difluoroethyl)-N-[6-methyl-5-(2-morpholin-4-yl-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide
CID 86297886

Frequently Asked Questions

What is the IUPAC name of 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide?
The IUPAC name of 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide (CID 158343634) is 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide.
What is the SMILES notation for 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide?
The canonical SMILES for 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide is Cc1ncc(NC(=O)c2cc(C(C)(C)C#N)ccn2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cc(C(C)(F)F)ccn2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(O)C(F)(F)F)c2)cc1-c1cnc(OC2CCOCC2)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cnc(OC(F)F)c(N2CCOCC2)c1.
What is the InChIKey of 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide?
The InChIKey is GRLOTZWUEFSPEV-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H31F3N4O5.C27H30N6O4.2C25H27F2N5O4.C24H23F4N5O3.C23H20F5N5O3/c1-18-24(15-22(17-33-18)35-27(38)20-4-2-3-19(13-20)26(37)29(30,31)32)21-14-25(36-7-11-40-12-8-36)28(34-16-21)41-23-5-9-39-10-6-23;1-18-22(19-12-24(33-6-9-36-10-7-33)26(31-15-19)37-11-8-34)14-21(16-30-18)32-25(35)23-13-20(4-5-29-23)27(2,3)17-28;1-15-19(17-10-20(32-6-8-35-9-7-32)23(30-13-17)36-24(26)27)12-18(14-29-15)31-22(33)16-4-5-28-21(11-16)25(2,3)34;1-16-20(17-11-22(32-5-8-35-9-6-32)24(30-14-17)36-10-7-33)13-19(15-29-16)31-23(34)21-12-18(3-4-28-21)25(2,26)27;1-14-18(16-9-19(33-5-7-35-8-6-33)22(31-12-16)36-23(25)26)11-17(13-30-14)32-21(34)15-3-4-29-20(10-15)24(2,27)28;1-13-17(15-8-18(33-4-6-35-7-5-33)21(31-11-15)36-22(24)25)10-16(12-30-13)32-20(34)14-2-3-29-19(9-14)23(26,27)28/h2-4,13-17,23,26,37H,5-12H2,1H3,(H,35,38);4-5,12-16,34H,6-11H2,1-3H3,(H,32,35);4-5,10-14,24,34H,6-9H2,1-3H3,(H,31,33);3-4,11-15,33H,5-10H2,1-2H3,(H,31,34);3-4,9-13,23H,5-8H2,1-2H3,(H,32,34);2-3,8-12,22H,4-7H2,1H3,(H,32,34).
What are the key properties of 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide?
4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide has a molecular weight of 3089.10 g/mol, XLogP of 24.19, 43 rotatable bonds, 10 hydrogen bond donors, and 47 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(2-cyanopropan-2-yl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;4-(1,1-difluoroethyl)-N-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-2-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[5-[6-(difluoromethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(2,2,2-trifluoro-1-hydroxyethyl)benzamide is sourced from PubChem (CID 158343634), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).