N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide

C153H129Cl6F8N17O24 — CID 158358372

About N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide

N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide (PubChem CID 158358372) has the molecular formula C153H129Cl6F8N17O24 and a molecular weight of 2954.51 g/mol. Its IUPAC name is N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide.

Molecular Properties

• Compound Name: N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide
• PubChem CID: 158358372
• Molecular Formula: C153H129Cl6F8N17O24
• Molecular Weight: 2954.51 g/mol
• Exact Mass: 2949.74
• IUPAC Name: N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide
• SMILES: Cc1cc2c(cc1-c1ccc(NC(=O)C(C)C)nc1)OC(F)(F)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)C(C)C)cn1)OC(F)(F)CO2.Cc1ccccc1C(=O)Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)C1CCC1.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)C1CCCC1.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)c1ccccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)c1ccccc1F
• InChI: InChI=1S/C21H17ClN2O3.C20H13ClF2N2O3.2C20H14ClFN2O3.C19H19ClN2O3.C18H17ClN2O3.C18H18F2N2O3.C17H17F2N3O3/c1-13-4-2-3-5-15(13)21(25)24-20-7-6-14(12-23-20)16-10-18-19(11-17(16)22)27-9-8-26-18;21-13-9-17-16(27-6-7-28-17)8-12(13)11-4-5-18(24-10-11)25-20(26)19-14(22)2-1-3-15(19)23;2*21-15-10-18-17(26-7-8-27-18)9-14(15)12-5-6-19(23-11-12)24-20(25)13-3-1-2-4-16(13)22;20-15-10-17-16(24-7-8-25-17)9-14(15)13-5-6-18(21-11-13)22-19(23)12-3-1-2-4-12;19-14-9-16-15(23-6-7-24-16)8-13(14)12-4-5-17(20-10-12)21-18(22)11-2-1-3-11;1-10(2)17(23)22-16-5-4-12(8-21-16)13-7-15-14(6-11(13)3)24-9-18(19,20)25-15;1-9(2)16(23)22-15-7-20-12(6-21-15)11-5-14-13(4-10(11)3)24-8-17(18,19)25-14/h2-7,10-12H,8-9H2,1H3,(H,23,24,25);1-5,8-10H,6-7H2,(H,24,25,26);2*1-6,9-11H,7-8H2,(H,23,24,25);5-6,9-12H,1-4,7-8H2,(H,21,22,23);4-5,8-11H,1-3,6-7H2,(H,20,21,22);4-8,10H,9H2,1-3H3,(H,21,22,23);4-7,9H,8H2,1-3H3,(H,21,22,23)
• InChIKey: GTDVHSQPVIGGIH-UHFFFAOYSA-N
• XLogP: 34.21
• TPSA: 496.49 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 33
• Rotatable Bonds: 24
• Heavy Atoms: 208
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2954.51
LogP ≤ 5	34.21
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide?

The IUPAC name of N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide (CID 158358372) is N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide.

What is the SMILES notation for N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide?

The canonical SMILES for N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide is Cc1cc2c(cc1-c1ccc(NC(=O)C(C)C)nc1)OC(F)(F)CO2.Cc1cc2c(cc1-c1cnc(NC(=O)C(C)C)cn1)OC(F)(F)CO2.Cc1ccccc1C(=O)Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)C1CCC1.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)C1CCCC1.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)c1c(F)cccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)c1ccccc1F.O=C(Nc1ccc(-c2cc3c(cc2Cl)OCCO3)cn1)c1ccccc1F.

What is the InChIKey of N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide?

The InChIKey is GTDVHSQPVIGGIH-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H17ClN2O3.C20H13ClF2N2O3.2C20H14ClFN2O3.C19H19ClN2O3.C18H17ClN2O3.C18H18F2N2O3.C17H17F2N3O3/c1-13-4-2-3-5-15(13)21(25)24-20-7-6-14(12-23-20)16-10-18-19(11-17(16)22)27-9-8-26-18;21-13-9-17-16(27-6-7-28-17)8-12(13)11-4-5-18(24-10-11)25-20(26)19-14(22)2-1-3-15(19)23;2*21-15-10-18-17(26-7-8-27-18)9-14(15)12-5-6-19(23-11-12)24-20(25)13-3-1-2-4-16(13)22;20-15-10-17-16(24-7-8-25-17)9-14(15)13-5-6-18(21-11-13)22-19(23)12-3-1-2-4-12;19-14-9-16-15(23-6-7-24-16)8-13(14)12-4-5-17(20-10-12)21-18(22)11-2-1-3-11;1-10(2)17(23)22-16-5-4-12(8-21-16)13-7-15-14(6-11(13)3)24-9-18(19,20)25-15;1-9(2)16(23)22-15-7-20-12(6-21-15)11-5-14-13(4-10(11)3)24-8-17(18,19)25-14/h2-7,10-12H,8-9H2,1H3,(H,23,24,25);1-5,8-10H,6-7H2,(H,24,25,26);2*1-6,9-11H,7-8H2,(H,23,24,25);5-6,9-12H,1-4,7-8H2,(H,21,22,23);4-5,8-11H,1-3,6-7H2,(H,20,21,22);4-8,10H,9H2,1-3H3,(H,21,22,23);4-7,9H,8H2,1-3H3,(H,21,22,23).

What are the key properties of N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide?

N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide has a molecular weight of 2954.51 g/mol, XLogP of 34.21, 24 rotatable bonds, 8 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclobutanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]cyclopentanecarboxamide;N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2,6-difluorobenzamide;bis(N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-fluorobenzamide);N-[5-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)-2-pyridinyl]-2-methylbenzamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)pyrazin-2-yl]-2-methylpropanamide;N-[5-(3,3-difluoro-7-methyl-2H-1,4-benzodioxin-6-yl)-2-pyridinyl]-2-methylpropanamide is sourced from PubChem (CID 158358372), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).