2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide

C₁₁₆H₁₀₀F₁₁N₁₅O₈S₄ — CID 158412212

About 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide

2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide (PubChem CID 158412212) has the molecular formula C₁₁₆H₁₀₀F₁₁N₁₅O₈S₄ and a molecular weight of 2169.42 g/mol. Its IUPAC name is 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide.

Molecular Properties

• Compound Name: 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide
• PubChem CID: 158412212
• Molecular Formula: C₁₁₆H₁₀₀F₁₁N₁₅O₈S₄
• Molecular Weight: 2169.42 g/mol
• Exact Mass: 2167.66
• IUPAC Name: 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide
• SMILES: CC(C)C(=O)Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1ccc(-c2c(C)sc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2c(C)sc3c2CCC3)cn1.Cc1sc2c(c1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CCC2.Cc1sc2c(c1-c1ccc(NC(=O)c3ccccc3F)nc1)CCC2.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1c(F)cccc1F
• InChI: InChI=1S/C21H20N2OS.C20H16F2N2OS.C20H17FN2OS.C20H19N3OS.C19H12F5N3O2.C16H16F3N3O2/c1-13-6-3-4-7-16(13)21(24)23-19-11-10-15(12-22-19)20-14(2)25-18-9-5-8-17(18)20;1-11-18(13-4-2-7-16(13)26-11)12-8-9-17(23-10-12)24-20(25)19-14(21)5-3-6-15(19)22;1-12-19(15-6-4-8-17(15)25-12)13-9-10-18(22-11-13)23-20(24)14-5-2-3-7-16(14)21;1-12-6-3-4-7-14(12)20(24)23-18-11-21-16(10-22-18)19-13(2)25-17-9-5-8-15(17)19;20-10-4-2-5-11(21)16(10)18(28)27-14-8-25-12(7-26-14)15-9-3-1-6-13(9)29-17(15)19(22,23)24;1-8(2)15(23)22-12-7-20-10(6-21-12)13-9-4-3-5-11(9)24-14(13)16(17,18)19/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H,22,23,24);3,5-6,8-10H,2,4,7H2,1H3,(H,23,24,25);2-3,5,7,9-11H,4,6,8H2,1H3,(H,22,23,24);3-4,6-7,10-11H,5,8-9H2,1-2H3,(H,22,23,24);2,4-5,7-8H,1,3,6H2,(H,26,27,28);6-8H,3-5H2,1-2H3,(H,21,22,23)
• InChIKey: GZLJSXHZFULHSF-UHFFFAOYSA-N
• XLogP: 28.48
• TPSA: 316.89 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 21
• Rotatable Bonds: 18
• Heavy Atoms: 154
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2169.42
LogP ≤ 5	28.48
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	21

Frequently Asked Questions

What is the IUPAC name of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

The IUPAC name of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide (CID 158412212) is 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide.

What is the SMILES notation for 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

The canonical SMILES for 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide is CC(C)C(=O)Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1ccc(-c2c(C)sc3c2CCC3)cn1.Cc1ccccc1C(=O)Nc1cnc(-c2c(C)sc3c2CCC3)cn1.Cc1sc2c(c1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CCC2.Cc1sc2c(c1-c1ccc(NC(=O)c3ccccc3F)nc1)CCC2.O=C(Nc1cnc(-c2c(C(F)(F)F)oc3c2CCC3)cn1)c1c(F)cccc1F.

What is the InChIKey of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

The InChIKey is GZLJSXHZFULHSF-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H20N2OS.C20H16F2N2OS.C20H17FN2OS.C20H19N3OS.C19H12F5N3O2.C16H16F3N3O2/c1-13-6-3-4-7-16(13)21(24)23-19-11-10-15(12-22-19)20-14(2)25-18-9-5-8-17(18)20;1-11-18(13-4-2-7-16(13)26-11)12-8-9-17(23-10-12)24-20(25)19-14(21)5-3-6-15(19)22;1-12-19(15-6-4-8-17(15)25-12)13-9-10-18(22-11-13)23-20(24)14-5-2-3-7-16(14)21;1-12-6-3-4-7-14(12)20(24)23-18-11-21-16(10-22-18)19-13(2)25-17-9-5-8-15(17)19;20-10-4-2-5-11(21)16(10)18(28)27-14-8-25-12(7-26-14)15-9-3-1-6-13(9)29-17(15)19(22,23)24;1-8(2)15(23)22-12-7-20-10(6-21-12)13-9-4-3-5-11(9)24-14(13)16(17,18)19/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H,22,23,24);3,5-6,8-10H,2,4,7H2,1H3,(H,23,24,25);2-3,5,7,9-11H,4,6,8H2,1H3,(H,22,23,24);3-4,6-7,10-11H,5,8-9H2,1-2H3,(H,22,23,24);2,4-5,7-8H,1,3,6H2,(H,26,27,28);6-8H,3-5H2,1-2H3,(H,21,22,23).

What are the key properties of 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide?

2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide has a molecular weight of 2169.42 g/mol, XLogP of 28.48, 18 rotatable bonds, 6 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for 2,6-difluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(2-methyl-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-2-pyridinyl]benzamide;2-methyl-N-[5-[2-(trifluoromethyl)-5,6-dihydro-4H-cyclopenta[b]furan-3-yl]pyrazin-2-yl]propanamide is sourced from PubChem (CID 158412212), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 158412212 — identifiers, structure, computed properties (public domain)

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