1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide

C214H222F8N64O12 — CID 158423532

IUPAC1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide
SMILESCC(C)CN(C)C(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CCONC(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.COC(C)CNC(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.COC1CC(NC(=O)C2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.COC1CC(NC(=O)C2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NC5CC(F)(F)C5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NCC(F)(F)F)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NCCC(F)(F)F)CC4)nc3)c3c(C#N)cnn3c2)cn1
InChIInChI=1S/2C28H30N8O2.C28H32N8O.C27H26F2N8O.C27H30N8O2.C26H25F3N8O.C25H23F3N8O.C25H26N8O2/c2*1-34-16-22(15-31-34)20-9-25(27-21(12-29)14-32-36(27)17-20)19-3-4-26(30-13-19)35-7-5-18(6-8-35)28(37)33-23-10-24(11-23)38-2;1-19(2)16-33(3)28(37)20-7-9-35(10-8-20)26-6-5-21(13-30-26)25-11-22(24-15-31-34(4)17-24)18-36-27(25)23(12-29)14-32-36;1-35-15-21(14-32-35)19-8-23(25-20(11-30)13-33-37(25)16-19)18-2-3-24(31-12-18)36-6-4-17(5-7-36)26(38)34-22-9-27(28,29)10-22;1-18(37-3)12-30-27(36)19-6-8-34(9-7-19)25-5-4-20(13-29-25)24-10-21(23-15-31-33(2)16-23)17-35-26(24)22(11-28)14-32-35;1-35-15-21(14-33-35)19-10-22(24-20(11-30)13-34-37(24)16-19)18-2-3-23(32-12-18)36-8-4-17(5-9-36)25(38)31-7-6-26(27,28)29;1-34-13-20(12-32-34)18-8-21(23-19(9-29)11-33-36(23)14-18)17-2-3-22(30-10-17)35-6-4-16(5-7-35)24(37)31-15-25(26,27)28;1-3-35-30-25(34)17-6-8-32(9-7-17)23-5-4-18(12-27-23)22-10-19(21-14-28-31(2)15-21)16-33-24(22)20(11-26)13-29-33/h2*3-4,9,13-18,23-24H,5-8,10-11H2,1-2H3,(H,33,37);5-6,11,13-15,17-20H,7-10,16H2,1-4H3;2-3,8,12-17,22H,4-7,9-10H2,1H3,(H,34,38);4-5,10,13-19H,6-9,12H2,1-3H3,(H,30,36);2-3,10,12-17H,4-9H2,1H3,(H,31,38);2-3,8,10-14,16H,4-7,15H2,1H3,(H,31,37);4-5,10,12-17H,3,6-9H2,1-2H3,(H,30,34)
InChIKeyHATTUROTFWFZQD-UHFFFAOYSA-N
MW4034.55 g/mol
LogP27.66
Rot. Bonds47

About 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide

1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide (PubChem CID 158423532) has the molecular formula C214H222F8N64O12 and a molecular weight of 4034.55 g/mol. Its IUPAC name is 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide.

Molecular Properties

Compound Name1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide
PubChem CID158423532
Molecular FormulaC214H222F8N64O12
Molecular Weight4034.55 g/mol
Exact Mass4031.86
IUPAC Name1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide
SMILESCC(C)CN(C)C(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CCONC(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.COC(C)CNC(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.COC1CC(NC(=O)C2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.COC1CC(NC(=O)C2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NC5CC(F)(F)C5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NCC(F)(F)F)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NCCC(F)(F)F)CC4)nc3)c3c(C#N)cnn3c2)cn1
InChIInChI=1S/2C28H30N8O2.C28H32N8O.C27H26F2N8O.C27H30N8O2.C26H25F3N8O.C25H23F3N8O.C25H26N8O2/c2*1-34-16-22(15-31-34)20-9-25(27-21(12-29)14-32-36(27)17-20)19-3-4-26(30-13-19)35-7-5-18(6-8-35)28(37)33-23-10-24(11-23)38-2;1-19(2)16-33(3)28(37)20-7-9-35(10-8-20)26-6-5-21(13-30-26)25-11-22(24-15-31-34(4)17-24)18-36-27(25)23(12-29)14-32-36;1-35-15-21(14-32-35)19-8-23(25-20(11-30)13-33-37(25)16-19)18-2-3-24(31-12-18)36-6-4-17(5-7-36)26(38)34-22-9-27(28,29)10-22;1-18(37-3)12-30-27(36)19-6-8-34(9-7-19)25-5-4-20(13-29-25)24-10-21(23-15-31-33(2)16-23)17-35-26(24)22(11-28)14-32-35;1-35-15-21(14-33-35)19-10-22(24-20(11-30)13-34-37(24)16-19)18-2-3-23(32-12-18)36-8-4-17(5-9-36)25(38)31-7-6-26(27,28)29;1-34-13-20(12-32-34)18-8-21(23-19(9-29)11-33-36(23)14-18)17-2-3-22(30-10-17)35-6-4-16(5-7-35)24(37)31-15-25(26,27)28;1-3-35-30-25(34)17-6-8-32(9-7-17)23-5-4-18(12-27-23)22-10-19(21-14-28-31(2)15-21)16-33-24(22)20(11-26)13-29-33/h2*3-4,9,13-18,23-24H,5-8,10-11H2,1-2H3,(H,33,37);5-6,11,13-15,17-20H,7-10,16H2,1-4H3;2-3,8,12-17,22H,4-7,9-10H2,1H3,(H,34,38);4-5,10,13-19H,6-9,12H2,1-3H3,(H,30,36);2-3,10,12-17H,4-9H2,1H3,(H,31,38);2-3,8,10-14,16H,4-7,15H2,1H3,(H,31,37);4-5,10,12-17H,3,6-9H2,1-2H3,(H,30,34)
InChIKeyHATTUROTFWFZQD-UHFFFAOYSA-N
XLogP27.66
TPSA861.25 Ų
H-Bond Donors7
H-Bond Acceptors68
Rotatable Bonds47
Heavy Atoms298
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004034.55
LogP ≤ 527.66
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1068

Analyze 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide with MolForge

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Related Compounds

US10023570, Example 235
CID 126740402
US10023570, Example 234
CID 126740060
US10023570, Example 240
CID 126740167
US10023570, Example 236
CID 126740198
US10023570, Example 239
CID 126740339
CID 158598881
CID 158598881
CID 160091335
CID 160091335
CID 160191054
CID 160191054
CID 160313354
CID 160313354
CID 160370194
CID 160370194
2-(3,4-dimethylpyrazol-1-yl)ethanol;2-(4,5-dimethylpyrazol-1-yl)ethanol;4-[2-(3,4-dimethylpyrazol-1-yl)ethyl]morpholine;4-[2-(4,5-dimethylpyrazol-1-yl)ethyl]morpholine;4-(3,4-dimethylpyrazol-1-yl)-1-methylpiperidine;4-(4,5-dimethylpyrazol-1-yl)-1-methylpiperidine;4-(3,4-dimethylpyrazol-1-yl)piperidine;1-(3,4-dimethylpyrazol-1-yl)-4,4,4-trifluorobutan-2-ol;1-(4,5-dimethylpyrazol-1-yl)-4,4,4-trifluorobutan-2-ol;3,5-dimethylpyridine;1,5-dimethyl-3H-pyrrolo[2,3-b]pyridin-2-one;N-ethyl-3,5-dimethylpyridine-2-carboxamide;2-(1-isocyanocyclobutyl)-5-methylpyridine;1-[(1-isocyanocyclopropyl)methyl]-3,4-dimethylpyrazole;1-[(1-isocyanocyclopropyl)methyl]-4,5-dimethylpyrazole;1-(2-methoxyethyl)-3,4-dimethylpyrazole;3-methyl-4-methyliminobut-2-en-2-amine;2-methyl-3-methyliminoprop-1-en-1-amine;5-methyl-2-(1-methylpiperidin-4-yl)pyridine;3-methylpyridine
CID 160707948
CID 161055503
CID 161055503

Frequently Asked Questions

What is the IUPAC name of 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide?
The IUPAC name of 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide (CID 158423532) is 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide.
What is the SMILES notation for 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide?
The canonical SMILES for 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide is CC(C)CN(C)C(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CCONC(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.COC(C)CNC(=O)C1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.COC1CC(NC(=O)C2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.COC1CC(NC(=O)C2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NC5CC(F)(F)C5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NCC(F)(F)F)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCC(C(=O)NCCC(F)(F)F)CC4)nc3)c3c(C#N)cnn3c2)cn1.
What is the InChIKey of 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide?
The InChIKey is HATTUROTFWFZQD-UHFFFAOYSA-N. The full InChI is InChI=1S/2C28H30N8O2.C28H32N8O.C27H26F2N8O.C27H30N8O2.C26H25F3N8O.C25H23F3N8O.C25H26N8O2/c2*1-34-16-22(15-31-34)20-9-25(27-21(12-29)14-32-36(27)17-20)19-3-4-26(30-13-19)35-7-5-18(6-8-35)28(37)33-23-10-24(11-23)38-2;1-19(2)16-33(3)28(37)20-7-9-35(10-8-20)26-6-5-21(13-30-26)25-11-22(24-15-31-34(4)17-24)18-36-27(25)23(12-29)14-32-36;1-35-15-21(14-32-35)19-8-23(25-20(11-30)13-33-37(25)16-19)18-2-3-24(31-12-18)36-6-4-17(5-7-36)26(38)34-22-9-27(28,29)10-22;1-18(37-3)12-30-27(36)19-6-8-34(9-7-19)25-5-4-20(13-29-25)24-10-21(23-15-31-33(2)16-23)17-35-26(24)22(11-28)14-32-35;1-35-15-21(14-33-35)19-10-22(24-20(11-30)13-34-37(24)16-19)18-2-3-23(32-12-18)36-8-4-17(5-9-36)25(38)31-7-6-26(27,28)29;1-34-13-20(12-32-34)18-8-21(23-19(9-29)11-33-36(23)14-18)17-2-3-22(30-10-17)35-6-4-16(5-7-35)24(37)31-15-25(26,27)28;1-3-35-30-25(34)17-6-8-32(9-7-17)23-5-4-18(12-27-23)22-10-19(21-14-28-31(2)15-21)16-33-24(22)20(11-26)13-29-33/h2*3-4,9,13-18,23-24H,5-8,10-11H2,1-2H3,(H,33,37);5-6,11,13-15,17-20H,7-10,16H2,1-4H3;2-3,8,12-17,22H,4-7,9-10H2,1H3,(H,34,38);4-5,10,13-19H,6-9,12H2,1-3H3,(H,30,36);2-3,10,12-17H,4-9H2,1H3,(H,31,38);2-3,8,10-14,16H,4-7,15H2,1H3,(H,31,37);4-5,10,12-17H,3,6-9H2,1-2H3,(H,30,34).
What are the key properties of 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide?
1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide has a molecular weight of 4034.55 g/mol, XLogP of 27.66, 47 rotatable bonds, 7 hydrogen bond donors, and 68 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3-difluorocyclobutyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-ethoxypiperidine-4-carboxamide;bis(1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3-methoxycyclobutyl)piperidine-4-carboxamide);1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxypropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-methyl-N-(2-methylpropyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide;1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(3,3,3-trifluoropropyl)piperidine-4-carboxamide is sourced from PubChem (CID 158423532), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).