5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide

C126H128F4N28O9 — CID 158501155

About 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide

5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide (PubChem CID 158501155) has the molecular formula C126H128F4N28O9 and a molecular weight of 2254.59 g/mol. Its IUPAC name is 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide.

Molecular Properties

• Compound Name: 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide
• PubChem CID: 158501155
• Molecular Formula: C126H128F4N28O9
• Molecular Weight: 2254.59 g/mol
• Exact Mass: 2253.04
• IUPAC Name: 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide
• SMILES: CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)C5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)CC5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N)c4)cc23)c1.O=C(Nc1ccc(O)cc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.O=C(Nc1ccc(O)cc1)c1n[nH]c2ccc(-c3cncc(CN4CCOCC4)c3)cc12
• InChI: InChI=1S/C28H30F2N6O.C27H28F2N6O.C25H25N5O3.C24H23N5O3.C22H22N6O/c1-35(2)17-19-4-3-5-23(13-19)32-27(37)26-24-14-21(6-7-25(24)33-34-26)22-12-20(15-31-16-22)18-36-10-8-28(29,30)9-11-36;1-34(2)15-18-4-3-5-22(11-18)31-26(36)25-23-12-20(6-7-24(23)32-33-25)21-10-19(13-30-14-21)16-35-9-8-27(28,29)17-35;31-20-4-2-19(3-5-20)27-25(33)24-22-12-17(1-6-23(22)28-29-24)18-11-16(13-26-14-18)15-30-9-7-21(32)8-10-30;30-20-4-2-19(3-5-20)26-24(31)23-21-12-17(1-6-22(21)27-28-23)18-11-16(13-25-14-18)15-29-7-9-32-10-8-29;1-28(2)13-14-4-3-5-18(8-14)25-22(29)21-19-10-15(6-7-20(19)26-27-21)16-9-17(23)12-24-11-16/h3-7,12-16H,8-11,17-18H2,1-2H3,(H,32,37)(H,33,34);3-7,10-14H,8-9,15-17H2,1-2H3,(H,31,36)(H,32,33);1-6,11-14,21,31-32H,7-10,15H2,(H,27,33)(H,28,29);1-6,11-14,30H,7-10,15H2,(H,26,31)(H,27,28);3-12H,13,23H2,1-2H3,(H,25,29)(H,26,27)
• InChIKey: HJXINWPYZDFLLQ-UHFFFAOYSA-N
• XLogP: 20.43
• TPSA: 471.97 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 27
• Rotatable Bonds: 29
• Heavy Atoms: 167
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2254.59
LogP ≤ 5	20.43
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	27

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroquinone', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?

The IUPAC name of 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide (CID 158501155) is 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide.

What is the SMILES notation for 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?

The canonical SMILES for 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide is CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)C5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(CN5CCC(F)(F)CC5)c4)cc23)c1.CN(C)Cc1cccc(NC(=O)c2n[nH]c3ccc(-c4cncc(N)c4)cc23)c1.O=C(Nc1ccc(O)cc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.O=C(Nc1ccc(O)cc1)c1n[nH]c2ccc(-c3cncc(CN4CCOCC4)c3)cc12.

What is the InChIKey of 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?

The InChIKey is HJXINWPYZDFLLQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30F2N6O.C27H28F2N6O.C25H25N5O3.C24H23N5O3.C22H22N6O/c1-35(2)17-19-4-3-5-23(13-19)32-27(37)26-24-14-21(6-7-25(24)33-34-26)22-12-20(15-31-16-22)18-36-10-8-28(29,30)9-11-36;1-34(2)15-18-4-3-5-22(11-18)31-26(36)25-23-12-20(6-7-24(23)32-33-25)21-10-19(13-30-14-21)16-35-9-8-27(28,29)17-35;31-20-4-2-19(3-5-20)27-25(33)24-22-12-17(1-6-23(22)28-29-24)18-11-16(13-26-14-18)15-30-9-7-21(32)8-10-30;30-20-4-2-19(3-5-20)26-24(31)23-21-12-17(1-6-22(21)27-28-23)18-11-16(13-25-14-18)15-29-7-9-32-10-8-29;1-28(2)13-14-4-3-5-18(8-14)25-22(29)21-19-10-15(6-7-20(19)26-27-21)16-9-17(23)12-24-11-16/h3-7,12-16H,8-11,17-18H2,1-2H3,(H,32,37)(H,33,34);3-7,10-14H,8-9,15-17H2,1-2H3,(H,31,36)(H,32,33);1-6,11-14,21,31-32H,7-10,15H2,(H,27,33)(H,28,29);1-6,11-14,30H,7-10,15H2,(H,26,31)(H,27,28);3-12H,13,23H2,1-2H3,(H,25,29)(H,26,27).

What are the key properties of 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide?

5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide has a molecular weight of 2254.59 g/mol, XLogP of 20.43, 29 rotatable bonds, 14 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 5-(5-amino-3-pyridinyl)-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[3-[(dimethylamino)methyl]phenyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-(4-hydroxyphenyl)-5-[5-(morpholin-4-ylmethyl)-3-pyridinyl]-1H-indazole-3-carboxamide is sourced from PubChem (CID 158501155), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).