3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide

C133H148Cl2F2N22O5S5 — CID 158550514

About 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide

3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide (PubChem CID 158550514) has the molecular formula C133H148Cl2F2N22O5S5 and a molecular weight of 2404.03 g/mol. Its IUPAC name is 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 158550514
• Molecular Formula: C133H148Cl2F2N22O5S5
• Molecular Weight: 2404.03 g/mol
• Exact Mass: 2401.00
• IUPAC Name: 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide
• SMILES: Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCC(CC5CC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCC5(CCCC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(-c4ccc(Cl)cc4)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(-c4cccc(Cl)c4)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(-c4cnn(C(F)F)c4)c3)sc2n1
• InChI: InChI=1S/2C28H29ClN4OS.C26H28F2N6OS.C26H32N4OS.C25H30N4OS/c1-18-5-11-22-25(30)26(35-28(22)32-18)27(34)31-14-13-19-6-12-24(33-15-3-2-4-16-33)23(17-19)20-7-9-21(29)10-8-20;1-18-8-10-22-25(30)26(35-28(22)32-18)27(34)31-13-12-19-9-11-24(33-14-3-2-4-15-33)23(16-19)20-6-5-7-21(29)17-20;1-16-5-7-19-22(29)23(36-25(19)32-16)24(35)30-10-9-17-6-8-21(33-11-3-2-4-12-33)20(13-17)18-14-31-34(15-18)26(27)28;1-18-5-10-21-22(27)23(32-25(21)29-18)24(31)28-15-11-19-6-8-20(9-7-19)30-16-4-14-26(17-30)12-2-3-13-26;1-16-2-9-21-22(26)23(31-25(21)28-16)24(30)27-12-10-17-5-7-20(8-6-17)29-13-11-19(15-29)14-18-3-4-18/h5-12,17H,2-4,13-16,30H2,1H3,(H,31,34);5-11,16-17H,2-4,12-15,30H2,1H3,(H,31,34);5-8,13-15,26H,2-4,9-12,29H2,1H3,(H,30,35);5-10H,2-4,11-17,27H2,1H3,(H,28,31);2,5-9,18-19H,3-4,10-15,26H2,1H3,(H,27,30)
• InChIKey: HPQTZNKTTIENAT-UHFFFAOYSA-N
• XLogP: 28.45
• TPSA: 374.07 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 27
• Rotatable Bonds: 31
• Heavy Atoms: 169
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2404.03
LogP ≤ 5	28.45
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	27

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_E(186)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide (CID 158550514) is 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide is Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCC(CC5CC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCC5(CCCC5)C4)cc3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(-c4ccc(Cl)cc4)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(-c4cccc(Cl)c4)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(-c4cnn(C(F)F)c4)c3)sc2n1.

What is the InChIKey of 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is HPQTZNKTTIENAT-UHFFFAOYSA-N. The full InChI is InChI=1S/2C28H29ClN4OS.C26H28F2N6OS.C26H32N4OS.C25H30N4OS/c1-18-5-11-22-25(30)26(35-28(22)32-18)27(34)31-14-13-19-6-12-24(33-15-3-2-4-16-33)23(17-19)20-7-9-21(29)10-8-20;1-18-8-10-22-25(30)26(35-28(22)32-18)27(34)31-13-12-19-9-11-24(33-14-3-2-4-15-33)23(16-19)20-6-5-7-21(29)17-20;1-16-5-7-19-22(29)23(36-25(19)32-16)24(35)30-10-9-17-6-8-21(33-11-3-2-4-12-33)20(13-17)18-14-31-34(15-18)26(27)28;1-18-5-10-21-22(27)23(32-25(21)29-18)24(31)28-15-11-19-6-8-20(9-7-19)30-16-4-14-26(17-30)12-2-3-13-26;1-16-2-9-21-22(26)23(31-25(21)28-16)24(30)27-12-10-17-5-7-20(8-6-17)29-13-11-19(15-29)14-18-3-4-18/h5-12,17H,2-4,13-16,30H2,1H3,(H,31,34);5-11,16-17H,2-4,12-15,30H2,1H3,(H,31,34);5-8,13-15,26H,2-4,9-12,29H2,1H3,(H,30,35);5-10H,2-4,11-17,27H2,1H3,(H,28,31);2,5-9,18-19H,3-4,10-15,26H2,1H3,(H,27,30).

What are the key properties of 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide?

3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2404.03 g/mol, XLogP of 28.45, 31 rotatable bonds, 10 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-[2-[4-(7-azaspiro[4.5]decan-7-yl)phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(3-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-(4-chlorophenyl)-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[4-[3-(cyclopropylmethyl)pyrrolidin-1-yl]phenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-[3-[1-(difluoromethyl)pyrazol-4-yl]-4-piperidin-1-ylphenyl]ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 158550514), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).