(2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide

C296H353Cl5F2N44O46S — CID 158650639

About (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide

(2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide (PubChem CID 158650639) has the molecular formula C296H353Cl5F2N44O46S and a molecular weight of 5510.67 g/mol. Its IUPAC name is (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide.

Molecular Properties

• Compound Name: (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide
• PubChem CID: 158650639
• Molecular Formula: C296H353Cl5F2N44O46S
• Molecular Weight: 5510.67 g/mol
• Exact Mass: 5504.48
• IUPAC Name: (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide
• SMILES: CC1(C)c2ccccc2CN1C(=O)[C@H](O)[C@@H](O)C(=O)NCC1CCN(c2ccccc2C#N)CC1.CCOc1cc(F)ccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2Cc3ccccc3C2(C)C)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)CC1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)CC1(C)c1nccs1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)CC1c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)C[C@@]1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)C[C@]1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCC1(C)c1ccccc1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ncccn1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@](C)(O)[C@@H](O)C(=O)N1CCCC1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.O=C(NCC1CCN(c2ccc(F)cc2OCCC2CCCCC2)CC1)[C@H](O)[C@@H](O)C(=O)N1CCCC1
• InChI: InChI=1S/C29H31FN2O5.3C28H33ClN4O4.C28H42FN3O5.2C27H31ClN4O4.C27H32N4O4.C26H30N4O4.C25H31N5O4S.C23H26N6O4/c1-4-37-24-15-21(30)13-14-22(24)19-11-9-18(10-12-19)16-31-27(35)25(33)26(34)28(36)32-17-20-7-5-6-8-23(20)29(32,2)3;3*1-18(19-9-11-22(12-10-19)33-14-6-13-30-33)31-25(36)23(34)24(35)26(37)32-17-27(2,3)16-28(32,4)20-7-5-8-21(29)15-20;29-22-8-9-23(24(18-22)37-17-12-20-6-2-1-3-7-20)31-15-10-21(11-16-31)19-30-27(35)25(33)26(34)28(36)32-13-4-5-14-32;1-18(19-9-11-22(12-10-19)32-16-6-14-29-32)30-25(35)27(3,36)23(33)24(34)31-15-5-13-26(31,2)20-7-4-8-21(28)17-20;1-17(18-8-10-21(11-9-18)32-13-5-12-29-32)30-25(35)23(33)24(34)26(36)31-16-27(2,3)15-22(31)19-6-4-7-20(28)14-19;1-27(2)21-9-5-3-8-20(21)17-31(27)26(35)24(33)23(32)25(34)29-16-18-11-13-30(14-12-18)22-10-6-4-7-19(22)15-28;1-18(19-10-12-21(13-11-19)30-17-7-15-27-30)28-24(33)22(31)23(32)25(34)29-16-6-14-26(29,2)20-8-4-3-5-9-20;1-16(17-6-8-18(9-7-17)30-12-5-10-27-30)28-21(33)19(31)20(32)22(34)29-15-24(2,3)14-25(29,4)23-26-11-13-35-23;1-15(16-6-8-17(9-7-16)29-14-4-12-26-29)27-22(32)19(30)20(31)23(33)28-13-2-5-18(28)21-24-10-3-11-25-21/h5-15,25-26,33-34H,4,16-17H2,1-3H3,(H,31,35);3*5-15,18,23-24,34-35H,16-17H2,1-4H3,(H,31,36);8-9,18,20-21,25-26,33-34H,1-7,10-17,19H2,(H,30,35);4,6-12,14,16-18,23,33,36H,5,13,15H2,1-3H3,(H,30,35);4-14,17,22-24,33-34H,15-16H2,1-3H3,(H,30,35);3-10,18,23-24,32-33H,11-14,16-17H2,1-2H3,(H,29,34);3-5,7-13,15,17-18,22-23,31-32H,6,14,16H2,1-2H3,(H,28,33);5-13,16,19-20,31-32H,14-15H2,1-4H3,(H,28,33);3-4,6-12,14-15,18-20,30-31H,2,5,13H2,1H3,(H,27,32)/t25-,26-;18-,23-,24-,28?;18-,23-,24-,28+;18-,23-,24-,28-;25-,26-;18-,23+,26?,27-;17-,22?,23-,24-;23-,24-;18-,22-,23-,26?;16-,19-,20-,25?;15-,18-,19-,20-/m11111111111/s1
• InChIKey: IBMXAPXDSVCGCR-DFAHYONUSA-N
• XLogP: 31.46
• TPSA: 1218.53 Ų
• H-Bond Donors: 33
• H-Bond Acceptors: 69
• Rotatable Bonds: 80
• Heavy Atoms: 394
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	5510.67
LogP ≤ 5	31.46
H-Bond Donors ≤ 5	33
H-Bond Acceptors ≤ 10	69

Frequently Asked Questions

What is the IUPAC name of (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

The IUPAC name of (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide (CID 158650639) is (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide.

What is the SMILES notation for (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

The canonical SMILES for (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide is CC1(C)c2ccccc2CN1C(=O)[C@H](O)[C@@H](O)C(=O)NCC1CCN(c2ccccc2C#N)CC1.CCOc1cc(F)ccc1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2Cc3ccccc3C2(C)C)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)CC1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)CC1(C)c1nccs1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)CC1c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)C[C@@]1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC(C)(C)C[C@]1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCC1(C)c1ccccc1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ncccn1)c1ccc(-n2cccn2)cc1.C[C@@H](NC(=O)[C@](C)(O)[C@@H](O)C(=O)N1CCCC1(C)c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1.O=C(NCC1CCN(c2ccc(F)cc2OCCC2CCCCC2)CC1)[C@H](O)[C@@H](O)C(=O)N1CCCC1.

What is the InChIKey of (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

The InChIKey is IBMXAPXDSVCGCR-DFAHYONUSA-N. The full InChI is InChI=1S/C29H31FN2O5.3C28H33ClN4O4.C28H42FN3O5.2C27H31ClN4O4.C27H32N4O4.C26H30N4O4.C25H31N5O4S.C23H26N6O4/c1-4-37-24-15-21(30)13-14-22(24)19-11-9-18(10-12-19)16-31-27(35)25(33)26(34)28(36)32-17-20-7-5-6-8-23(20)29(32,2)3;3*1-18(19-9-11-22(12-10-19)33-14-6-13-30-33)31-25(36)23(34)24(35)26(37)32-17-27(2,3)16-28(32,4)20-7-5-8-21(29)15-20;29-22-8-9-23(24(18-22)37-17-12-20-6-2-1-3-7-20)31-15-10-21(11-16-31)19-30-27(35)25(33)26(34)28(36)32-13-4-5-14-32;1-18(19-9-11-22(12-10-19)32-16-6-14-29-32)30-25(35)27(3,36)23(33)24(34)31-15-5-13-26(31,2)20-7-4-8-21(28)17-20;1-17(18-8-10-21(11-9-18)32-13-5-12-29-32)30-25(35)23(33)24(34)26(36)31-16-27(2,3)15-22(31)19-6-4-7-20(28)14-19;1-27(2)21-9-5-3-8-20(21)17-31(27)26(35)24(33)23(32)25(34)29-16-18-11-13-30(14-12-18)22-10-6-4-7-19(22)15-28;1-18(19-10-12-21(13-11-19)30-17-7-15-27-30)28-24(33)22(31)23(32)25(34)29-16-6-14-26(29,2)20-8-4-3-5-9-20;1-16(17-6-8-18(9-7-17)30-12-5-10-27-30)28-21(33)19(31)20(32)22(34)29-15-24(2,3)14-25(29,4)23-26-11-13-35-23;1-15(16-6-8-17(9-7-16)29-14-4-12-26-29)27-22(32)19(30)20(31)23(33)28-13-2-5-18(28)21-24-10-3-11-25-21/h5-15,25-26,33-34H,4,16-17H2,1-3H3,(H,31,35);3*5-15,18,23-24,34-35H,16-17H2,1-4H3,(H,31,36);8-9,18,20-21,25-26,33-34H,1-7,10-17,19H2,(H,30,35);4,6-12,14,16-18,23,33,36H,5,13,15H2,1-3H3,(H,30,35);4-14,17,22-24,33-34H,15-16H2,1-3H3,(H,30,35);3-10,18,23-24,32-33H,11-14,16-17H2,1-2H3,(H,29,34);3-5,7-13,15,17-18,22-23,31-32H,6,14,16H2,1-2H3,(H,28,33);5-13,16,19-20,31-32H,14-15H2,1-4H3,(H,28,33);3-4,6-12,14-15,18-20,30-31H,2,5,13H2,1H3,(H,27,32)/t25-,26-;18-,23-,24-,28?;18-,23-,24-,28+;18-,23-,24-,28-;25-,26-;18-,23+,26?,27-;17-,22?,23-,24-;23-,24-;18-,22-,23-,26?;16-,19-,20-,25?;15-,18-,19-,20-/m11111111111/s1.

What are the key properties of (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide?

(2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide has a molecular weight of 5510.67 g/mol, XLogP of 31.46, 80 rotatable bonds, 33 hydrogen bond donors, and 69 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,3R)-4-[2-(3-chlorophenyl)-4,4-dimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2-methylpyrrolidin-1-yl]-2,3-dihydroxy-2-methyl-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[(2S)-2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-4-[2-(3-chlorophenyl)-2,4,4-trimethylpyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-N-[[1-(2-cyanophenyl)piperidin-4-yl]methyl]-4-(3,3-dimethyl-1H-isoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-N-[[1-[2-(2-cyclohexylethoxy)-4-fluorophenyl]piperidin-4-yl]methyl]-2,3-dihydroxy-4-oxo-4-pyrrolidin-1-ylbutanamide;(2R,3R)-2,3-dihydroxy-4-(2-methyl-2-phenylpyrrolidin-1-yl)-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[(2R)-2-pyrimidin-2-ylpyrrolidin-1-yl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]-4-[2,4,4-trimethyl-2-(1,3-thiazol-2-yl)pyrrolidin-1-yl]butanamide;(2R,3R)-4-(3,3-dimethyl-1H-isoindol-2-yl)-N-[[4-(2-ethoxy-4-fluorophenyl)phenyl]methyl]-2,3-dihydroxy-4-oxobutanamide is sourced from PubChem (CID 158650639), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).