4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide

C₁₄₉H₁₆₄FN₁₇O₁₆S — CID 158856755

About 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide

4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide (PubChem CID 158856755) has the molecular formula C₁₄₉H₁₆₄FN₁₇O₁₆S and a molecular weight of 2500.12 g/mol. Its IUPAC name is 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide.

Molecular Properties

• Compound Name: 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide
• PubChem CID: 158856755
• Molecular Formula: C₁₄₉H₁₆₄FN₁₇O₁₆S
• Molecular Weight: 2500.12 g/mol
• Exact Mass: 2498.22
• IUPAC Name: 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide
• SMILES: CCN1CCC2(CC1)CC(=O)c1cc(-c3ccc(C(=O)NCc4cccs4)cn3)ccc1O2.COCCCCN1CCC2(CC1)CC(=O)c1cc(-c3ccc(C(=O)NCc4cncc(C)c4)cn3)ccc1O2.Cc1cncc(CNC(=O)c2ccc(-c3ccc4c(c3)C(=O)CC3(CCN(C(C)C)CC3)O4)cc2)c1.Cc1cncc(CNC(=O)c2ccc(-c3ccc4c(n3)C(=O)CC3(CCN(CCC(C)C)CC3)O4)cc2)c1.O=C(NCc1cccc(F)c1)c1ccc(-c2ccc3c(n2)C(=O)CC2(CCN(CC4CCC4)CC2)O3)cc1
• InChI: InChI=1S/C31H32FN3O3.C31H36N4O4.C31H36N4O3.C30H33N3O3.C26H27N3O3S/c32-25-6-2-5-22(17-25)19-33-30(37)24-9-7-23(8-10-24)26-11-12-28-29(34-26)27(36)18-31(38-28)13-15-35(16-14-31)20-21-3-1-4-21;1-22-15-23(19-32-18-22)20-34-30(37)25-5-7-27(33-21-25)24-6-8-29-26(16-24)28(36)17-31(39-29)9-12-35(13-10-31)11-3-4-14-38-2;1-21(2)10-13-35-14-11-31(12-15-35)17-27(36)29-28(38-31)9-8-26(34-29)24-4-6-25(7-5-24)30(37)33-20-23-16-22(3)18-32-19-23;1-20(2)33-12-10-30(11-13-33)16-27(34)26-15-25(8-9-28(26)36-30)23-4-6-24(7-5-23)29(35)32-19-22-14-21(3)17-31-18-22;1-2-29-11-9-26(10-12-29)15-23(30)21-14-18(6-8-24(21)32-26)22-7-5-19(16-27-22)25(31)28-17-20-4-3-13-33-20/h2,5-12,17,21H,1,3-4,13-16,18-20H2,(H,33,37);5-8,15-16,18-19,21H,3-4,9-14,17,20H2,1-2H3,(H,34,37);4-9,16,18-19,21H,10-15,17,20H2,1-3H3,(H,33,37);4-9,14-15,17-18,20H,10-13,16,19H2,1-3H3,(H,32,35);3-8,13-14,16H,2,9-12,15,17H2,1H3,(H,28,31)
• InChIKey: JADOFWZJXHRJQP-UHFFFAOYSA-N
• XLogP: 25.01
• TPSA: 392.66 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 29
• Rotatable Bonds: 32
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2500.12
LogP ≤ 5	25.01
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide?

The IUPAC name of 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide (CID 158856755) is 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide.

What is the SMILES notation for 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide?

The canonical SMILES for 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide is CCN1CCC2(CC1)CC(=O)c1cc(-c3ccc(C(=O)NCc4cccs4)cn3)ccc1O2.COCCCCN1CCC2(CC1)CC(=O)c1cc(-c3ccc(C(=O)NCc4cncc(C)c4)cn3)ccc1O2.Cc1cncc(CNC(=O)c2ccc(-c3ccc4c(c3)C(=O)CC3(CCN(C(C)C)CC3)O4)cc2)c1.Cc1cncc(CNC(=O)c2ccc(-c3ccc4c(n3)C(=O)CC3(CCN(CCC(C)C)CC3)O4)cc2)c1.O=C(NCc1cccc(F)c1)c1ccc(-c2ccc3c(n2)C(=O)CC2(CCN(CC4CCC4)CC2)O3)cc1.

What is the InChIKey of 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide?

The InChIKey is JADOFWZJXHRJQP-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H32FN3O3.C31H36N4O4.C31H36N4O3.C30H33N3O3.C26H27N3O3S/c32-25-6-2-5-22(17-25)19-33-30(37)24-9-7-23(8-10-24)26-11-12-28-29(34-26)27(36)18-31(38-28)13-15-35(16-14-31)20-21-3-1-4-21;1-22-15-23(19-32-18-22)20-34-30(37)25-5-7-27(33-21-25)24-6-8-29-26(16-24)28(36)17-31(39-29)9-12-35(13-10-31)11-3-4-14-38-2;1-21(2)10-13-35-14-11-31(12-15-35)17-27(36)29-28(38-31)9-8-26(34-29)24-4-6-25(7-5-24)30(37)33-20-23-16-22(3)18-32-19-23;1-20(2)33-12-10-30(11-13-33)16-27(34)26-15-25(8-9-28(26)36-30)23-4-6-24(7-5-23)29(35)32-19-22-14-21(3)17-31-18-22;1-2-29-11-9-26(10-12-29)15-23(30)21-14-18(6-8-24(21)32-26)22-7-5-19(16-27-22)25(31)28-17-20-4-3-13-33-20/h2,5-12,17,21H,1,3-4,13-16,18-20H2,(H,33,37);5-8,15-16,18-19,21H,3-4,9-14,17,20H2,1-2H3,(H,34,37);4-9,16,18-19,21H,10-15,17,20H2,1-3H3,(H,33,37);4-9,14-15,17-18,20H,10-13,16,19H2,1-3H3,(H,32,35);3-8,13-14,16H,2,9-12,15,17H2,1H3,(H,28,31).

What are the key properties of 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide?

4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide has a molecular weight of 2500.12 g/mol, XLogP of 25.01, 32 rotatable bonds, 5 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[1'-(cyclobutylmethyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(3-fluorophenyl)methyl]benzamide;6-(1'-ethyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)-N-(thiophen-2-ylmethyl)pyridine-3-carboxamide;6-[1'-(4-methoxybutyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]pyridine-3-carboxamide;4-[1'-(3-methylbutyl)-4-oxospiro[3H-pyrano[3,2-b]pyridine-2,4'-piperidine]-6-yl]-N-[(5-methyl-3-pyridinyl)methyl]benzamide;N-[(5-methyl-3-pyridinyl)methyl]-4-(4-oxo-1'-propan-2-ylspiro[3H-chromene-2,4'-piperidine]-6-yl)benzamide is sourced from PubChem (CID 158856755), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 158856755 — identifiers, structure, computed properties (public domain)

How this page is built: methodology · editorial policy & corrections.