3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate

C193H227F2N39O15S — CID 159036525

IUPAC3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(-c3ccncc3)s1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3nonc3c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1OCC(N)=O)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc(N3CCOCC3)n1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccc(F)c(F)c3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccccc3C#N)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N)nc1)C(=O)N2.COC(=O)COc1ccccc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C27H28N6O.C26H27F2N5O.C25H28N4OS.C25H31N3O4.C24H32N6O2.C24H30N4O3.C22H25N5O2.C20H26N6O/c1-32(2)27(21-9-4-3-5-10-21)14-12-26(13-15-27)19-33(25(34)31-26)22-17-29-24(30-18-22)23-11-7-6-8-20(23)16-28;1-32(2)26(19-6-4-3-5-7-19)12-10-25(11-13-26)17-33(24(34)31-25)20-15-29-23(30-16-20)18-8-9-21(27)22(28)14-18;1-28(2)25(20-6-4-3-5-7-20)14-12-24(13-15-25)18-29(23(30)27-24)22-9-8-21(31-22)19-10-16-26-17-11-19;1-27(2)25(19-9-5-4-6-10-19)15-13-24(14-16-25)18-28(23(30)26-24)20-11-7-8-12-21(20)32-17-22(29)31-3;1-28(2)24(19-6-4-3-5-7-19)11-9-23(10-12-24)18-30(22(31)27-23)20-8-13-25-21(26-20)29-14-16-32-17-15-29;1-27(2)24(18-8-4-3-5-9-18)14-12-23(13-15-24)17-28(22(30)26-23)19-10-6-7-11-20(19)31-16-21(25)29;1-26(2)22(16-6-4-3-5-7-16)12-10-21(11-13-22)15-27(20(28)23-21)17-8-9-18-19(14-17)25-29-24-18;1-25(2)20(15-6-4-3-5-7-15)10-8-19(9-11-20)14-26(18(27)24-19)16-12-22-17(21)23-13-16/h3-11,17-18H,12-15,19H2,1-2H3,(H,31,34);3-9,14-16H,10-13,17H2,1-2H3,(H,31,34);3-11,16-17H,12-15,18H2,1-2H3,(H,27,30);4-12H,13-18H2,1-3H3,(H,26,30);3-8,13H,9-12,14-18H2,1-2H3,(H,27,31);3-11H,12-17H2,1-2H3,(H2,25,29)(H,26,30);3-9,14H,10-13,15H2,1-2H3,(H,23,28);3-7,12-13H,8-11,14H2,1-2H3,(H,24,27)(H2,21,22,23)
InChIKeyJVNGMXCFVRLECX-UHFFFAOYSA-N
MW3403.26 g/mol
LogP29.03
Rot. Bonds34

About 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate

3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate (PubChem CID 159036525) has the molecular formula C193H227F2N39O15S and a molecular weight of 3403.26 g/mol. Its IUPAC name is 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate.

Molecular Properties

Compound Name3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate
PubChem CID159036525
Molecular FormulaC193H227F2N39O15S
Molecular Weight3403.26 g/mol
Exact Mass3400.79
IUPAC Name3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(-c3ccncc3)s1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3nonc3c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1OCC(N)=O)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc(N3CCOCC3)n1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccc(F)c(F)c3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccccc3C#N)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N)nc1)C(=O)N2.COC(=O)COc1ccccc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C27H28N6O.C26H27F2N5O.C25H28N4OS.C25H31N3O4.C24H32N6O2.C24H30N4O3.C22H25N5O2.C20H26N6O/c1-32(2)27(21-9-4-3-5-10-21)14-12-26(13-15-27)19-33(25(34)31-26)22-17-29-24(30-18-22)23-11-7-6-8-20(23)16-28;1-32(2)26(19-6-4-3-5-7-19)12-10-25(11-13-26)17-33(24(34)31-25)20-15-29-23(30-16-20)18-8-9-21(27)22(28)14-18;1-28(2)25(20-6-4-3-5-7-20)14-12-24(13-15-25)18-29(23(30)27-24)22-9-8-21(31-22)19-10-16-26-17-11-19;1-27(2)25(19-9-5-4-6-10-19)15-13-24(14-16-25)18-28(23(30)26-24)20-11-7-8-12-21(20)32-17-22(29)31-3;1-28(2)24(19-6-4-3-5-7-19)11-9-23(10-12-24)18-30(22(31)27-23)20-8-13-25-21(26-20)29-14-16-32-17-15-29;1-27(2)24(18-8-4-3-5-9-18)14-12-23(13-15-24)17-28(22(30)26-23)19-10-6-7-11-20(19)31-16-21(25)29;1-26(2)22(16-6-4-3-5-7-16)12-10-21(11-13-22)15-27(20(28)23-21)17-8-9-18-19(14-17)25-29-24-18;1-25(2)20(15-6-4-3-5-7-15)10-8-19(9-11-20)14-26(18(27)24-19)16-12-22-17(21)23-13-16/h3-11,17-18H,12-15,19H2,1-2H3,(H,31,34);3-9,14-16H,10-13,17H2,1-2H3,(H,31,34);3-11,16-17H,12-15,18H2,1-2H3,(H,27,30);4-12H,13-18H2,1-3H3,(H,26,30);3-8,13H,9-12,14-18H2,1-2H3,(H,27,31);3-11H,12-17H2,1-2H3,(H2,25,29)(H,26,30);3-9,14H,10-13,15H2,1-2H3,(H,23,28);3-7,12-13H,8-11,14H2,1-2H3,(H,24,27)(H2,21,22,23)
InChIKeyJVNGMXCFVRLECX-UHFFFAOYSA-N
XLogP29.03
TPSA589.70 Ų
H-Bond Donors10
H-Bond Acceptors38
Rotatable Bonds34
Heavy Atoms250
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003403.26
LogP ≤ 529.03
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1038

Analyze 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate with MolForge

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Related Compounds

3-(2,1,3-Benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-methylpyrazin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;8-(dimethylamino)-8-phenyl-3-pyrazin-2-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one
CID 157207907
2-[2-[8-(Dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetic acid;8-(dimethylamino)-8-phenyl-3-(2-piperidin-1-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(2-pyrimidin-5-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(2-pyrrolidin-1-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;bis(8-(dimethylamino)-8-thiophen-2-yl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one)
CID 158769991
3-(2,1,3-Benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-[2-hydroxyethyl(methyl)amino]pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-methylpyrazin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;8-(dimethylamino)-8-phenyl-3-pyrazin-2-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one
CID 160448807
8-Benzyl-8-(dimethylamino)-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetic acid;8-(dimethylamino)-8-phenyl-3-(2-piperidin-1-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;bis(8-(dimethylamino)-8-thiophen-2-yl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one)
CID 161459703
3-(2,1,3-Benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-methylpyrazin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;8-(dimethylamino)-8-phenyl-3-pyrazin-2-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate
CID 158838941
3-(2,1,3-Benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-methylpyrazin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;8-(dimethylamino)-8-phenyl-3-pyrazin-2-yl-1,3-diazaspiro[4.5]decan-2-one
CID 158943290
3-[2-(3,4-Difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate
CID 159473292
3-(2-Aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(5-fluoropyrimidin-2-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-pyrazin-2-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate
CID 159981310
3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;N-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide;2-[4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]piperazin-1-yl]acetamide;8-(dimethylamino)-8-phenyl-3-(6-piperazin-1-yl-3-pyridinyl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate
CID 160974391

Frequently Asked Questions

What is the IUPAC name of 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate?
The IUPAC name of 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate (CID 159036525) is 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate.
What is the SMILES notation for 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate?
The canonical SMILES for 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate is CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(-c3ccncc3)s1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3nonc3c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccccc1OCC(N)=O)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccnc(N3CCOCC3)n1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccc(F)c(F)c3)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(-c3ccccc3C#N)nc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(N)nc1)C(=O)N2.COC(=O)COc1ccccc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.
What is the InChIKey of 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate?
The InChIKey is JVNGMXCFVRLECX-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H28N6O.C26H27F2N5O.C25H28N4OS.C25H31N3O4.C24H32N6O2.C24H30N4O3.C22H25N5O2.C20H26N6O/c1-32(2)27(21-9-4-3-5-10-21)14-12-26(13-15-27)19-33(25(34)31-26)22-17-29-24(30-18-22)23-11-7-6-8-20(23)16-28;1-32(2)26(19-6-4-3-5-7-19)12-10-25(11-13-26)17-33(24(34)31-25)20-15-29-23(30-16-20)18-8-9-21(27)22(28)14-18;1-28(2)25(20-6-4-3-5-7-20)14-12-24(13-15-25)18-29(23(30)27-24)22-9-8-21(31-22)19-10-16-26-17-11-19;1-27(2)25(19-9-5-4-6-10-19)15-13-24(14-16-25)18-28(23(30)26-24)20-11-7-8-12-21(20)32-17-22(29)31-3;1-28(2)24(19-6-4-3-5-7-19)11-9-23(10-12-24)18-30(22(31)27-23)20-8-13-25-21(26-20)29-14-16-32-17-15-29;1-27(2)24(18-8-4-3-5-9-18)14-12-23(13-15-24)17-28(22(30)26-23)19-10-6-7-11-20(19)31-16-21(25)29;1-26(2)22(16-6-4-3-5-7-16)12-10-21(11-13-22)15-27(20(28)23-21)17-8-9-18-19(14-17)25-29-24-18;1-25(2)20(15-6-4-3-5-7-15)10-8-19(9-11-20)14-26(18(27)24-19)16-12-22-17(21)23-13-16/h3-11,17-18H,12-15,19H2,1-2H3,(H,31,34);3-9,14-16H,10-13,17H2,1-2H3,(H,31,34);3-11,16-17H,12-15,18H2,1-2H3,(H,27,30);4-12H,13-18H2,1-3H3,(H,26,30);3-8,13H,9-12,14-18H2,1-2H3,(H,27,31);3-11H,12-17H2,1-2H3,(H2,25,29)(H,26,30);3-9,14H,10-13,15H2,1-2H3,(H,23,28);3-7,12-13H,8-11,14H2,1-2H3,(H,24,27)(H2,21,22,23).
What are the key properties of 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate?
3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate has a molecular weight of 3403.26 g/mol, XLogP of 29.03, 34 rotatable bonds, 10 hydrogen bond donors, and 38 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(2-aminopyrimidin-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,1,3-benzoxadiazol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(3,4-difluorophenyl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-4-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetamide;2-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(5-pyridin-4-ylthiophen-2-yl)-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]phenoxy]acetate is sourced from PubChem (CID 159036525), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).