N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide

C118H117F5N30O16S4 — CID 159149177

About N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide

N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide (PubChem CID 159149177) has the molecular formula C118H117F5N30O16S4 and a molecular weight of 2434.69 g/mol. Its IUPAC name is N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide.

Molecular Properties

• Compound Name: N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide
• PubChem CID: 159149177
• Molecular Formula: C118H117F5N30O16S4
• Molecular Weight: 2434.69 g/mol
• Exact Mass: 2432.81
• IUPAC Name: N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide
• SMILES: CC(=O)N(C)c1ncc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cn1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1c[nH]c(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(CC(C)C)nc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(CCC(N)=O)nc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(N(C)CC(N)=O)nc(S(C)(=O)=O)c1
• InChI: InChI=1S/C26H28FN5O3S.C25H26FN7O4S.C25H25FN6O4S.C21H18FN7O2.C21H20FN5O3S/c1-5-23(17-11-19(10-16(2)3)30-25(12-17)36(4,34)35)31-26(33)22-13-28-15-24-21(22)14-29-32(24)20-8-6-18(27)7-9-20;1-4-20(15-9-23(32(2)14-22(27)34)31-24(10-15)38(3,36)37)30-25(35)19-11-28-13-21-18(19)12-29-33(21)17-7-5-16(26)6-8-17;1-3-21(15-10-17(6-9-23(27)33)30-24(11-15)37(2,35)36)31-25(34)20-12-28-14-22-19(20)13-29-32(22)18-7-4-16(26)5-8-18;1-13(30)28(2)21-25-8-14(9-26-21)7-24-20(31)18-10-23-12-19-17(18)11-27-29(19)16-5-3-15(22)4-6-16;1-3-18(13-8-20(24-9-13)31(2,29)30)26-21(28)17-10-23-12-19-16(17)11-25-27(19)15-6-4-14(22)5-7-15/h6-9,11-16,23H,5,10H2,1-4H3,(H,31,33);5-13,20H,4,14H2,1-3H3,(H2,27,34)(H,30,35);4-5,7-8,10-14,21H,3,6,9H2,1-2H3,(H2,27,33)(H,31,34);3-6,8-12H,7H2,1-2H3,(H,24,31);4-12,18,24H,3H2,1-2H3,(H,26,28)/t23-;20-;21-;;18-/m000.0/s1
• InChIKey: KJBGMDDCKZZFIZ-TWCYKWDBSA-N
• XLogP: 14.69
• TPSA: 625.58 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 37
• Rotatable Bonds: 37
• Heavy Atoms: 173
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2434.69
LogP ≤ 5	14.69
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The IUPAC name of N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide (CID 159149177) is N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide.

What is the SMILES notation for N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The canonical SMILES for N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide is CC(=O)N(C)c1ncc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cn1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1c[nH]c(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(CC(C)C)nc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(CCC(N)=O)nc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(N(C)CC(N)=O)nc(S(C)(=O)=O)c1.

What is the InChIKey of N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The InChIKey is KJBGMDDCKZZFIZ-TWCYKWDBSA-N. The full InChI is InChI=1S/C26H28FN5O3S.C25H26FN7O4S.C25H25FN6O4S.C21H18FN7O2.C21H20FN5O3S/c1-5-23(17-11-19(10-16(2)3)30-25(12-17)36(4,34)35)31-26(33)22-13-28-15-24-21(22)14-29-32(24)20-8-6-18(27)7-9-20;1-4-20(15-9-23(32(2)14-22(27)34)31-24(10-15)38(3,36)37)30-25(35)19-11-28-13-21-18(19)12-29-33(21)17-7-5-16(26)6-8-17;1-3-21(15-10-17(6-9-23(27)33)30-24(11-15)37(2,35)36)31-25(34)20-12-28-14-22-19(20)13-29-32(22)18-7-4-16(26)5-8-18;1-13(30)28(2)21-25-8-14(9-26-21)7-24-20(31)18-10-23-12-19-17(18)11-27-29(19)16-5-3-15(22)4-6-16;1-3-18(13-8-20(24-9-13)31(2,29)30)26-21(28)17-10-23-12-19-16(17)11-25-27(19)15-6-4-14(22)5-7-15/h6-9,11-16,23H,5,10H2,1-4H3,(H,31,33);5-13,20H,4,14H2,1-3H3,(H2,27,34)(H,30,35);4-5,7-8,10-14,21H,3,6,9H2,1-2H3,(H2,27,33)(H,31,34);3-6,8-12H,7H2,1-2H3,(H,24,31);4-12,18,24H,3H2,1-2H3,(H,26,28)/t23-;20-;21-;;18-/m000.0/s1.

What are the key properties of N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide has a molecular weight of 2434.69 g/mol, XLogP of 14.69, 37 rotatable bonds, 8 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for N-[[2-[acetyl(methyl)amino]pyrimidin-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-[(2-amino-2-oxoethyl)-methylamino]-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(3-amino-3-oxopropyl)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(2-methylpropyl)-6-methylsulfonyl-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(5-methylsulfonyl-1H-pyrrol-3-yl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide is sourced from PubChem (CID 159149177), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).