N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile

C145H148F6N26O17S6 — CID 159201090

IUPACN-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile
SMILESCC(C)NS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(OC(F)(F)F)cc3n2CC2CC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(-n4cccn4)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ccccn4)cc3n2CC2CC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2CC2CC2)c(C)c1.CCOc1ccc2c(C#N)c(-c3ccc(NS(=O)(=O)NC(C)C)cc3)n(CC)c2c1.CCn1c(-c2ccc(NS(=O)(=O)NC(C)C)cc2)c(C#N)c2ccc(OC(F)(F)F)cc21
InChIInChI=1S/C27H27N5O3S.C27H26N4O3S.C25H25N5O2S.C23H23F3N4O3S.C22H26N4O3S.C21H21F3N4O3S/c1-3-13-36(33,34)31-20-7-9-22(18(2)14-20)26-24(16-28)23-10-8-21(35-27-29-11-4-12-30-27)15-25(23)32(26)17-19-5-6-19;1-2-15-35(32,33)30-21-10-8-20(9-11-21)27-24(17-28)23-13-12-22(34-26-5-3-4-14-29-26)16-25(23)31(27)18-19-6-7-19;1-2-15-33(31,32)28-19-9-7-18(8-10-19)25-23(17-26)22-12-11-21(29-14-4-13-27-29)16-24(22)30(25)20-5-3-6-20;1-14(2)28-34(31,32)29-17-7-5-16(6-8-17)22-20(12-27)19-10-9-18(33-23(24,25)26)11-21(19)30(22)13-15-3-4-15;1-5-26-21-13-18(29-6-2)11-12-19(21)20(14-23)22(26)16-7-9-17(10-8-16)25-30(27,28)24-15(3)4;1-4-28-19-11-16(31-21(22,23)24)9-10-17(19)18(12-25)20(28)14-5-7-15(8-6-14)27-32(29,30)26-13(2)3/h4,7-12,14-15,19,31H,3,5-6,13,17H2,1-2H3;3-5,8-14,16,19,30H,2,6-7,15,18H2,1H3;4,7-14,16,20,28H,2-3,5-6,15H2,1H3;5-11,14-15,28-29H,3-4,13H2,1-2H3;7-13,15,24-25H,5-6H2,1-4H3;5-11,13,26-27H,4H2,1-3H3
InChIKeyKPHMXQUUYHGWHY-UHFFFAOYSA-N
MW2833.33 g/mol
LogP30.95
Rot. Bonds48

About N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile

N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile (PubChem CID 159201090) has the molecular formula C145H148F6N26O17S6 and a molecular weight of 2833.33 g/mol. Its IUPAC name is N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile.

Molecular Properties

Compound NameN-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile
PubChem CID159201090
Molecular FormulaC145H148F6N26O17S6
Molecular Weight2833.33 g/mol
Exact Mass2830.97
IUPAC NameN-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile
SMILESCC(C)NS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(OC(F)(F)F)cc3n2CC2CC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(-n4cccn4)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ccccn4)cc3n2CC2CC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2CC2CC2)c(C)c1.CCOc1ccc2c(C#N)c(-c3ccc(NS(=O)(=O)NC(C)C)cc3)n(CC)c2c1.CCn1c(-c2ccc(NS(=O)(=O)NC(C)C)cc2)c(C#N)c2ccc(OC(F)(F)F)cc21
InChIInChI=1S/C27H27N5O3S.C27H26N4O3S.C25H25N5O2S.C23H23F3N4O3S.C22H26N4O3S.C21H21F3N4O3S/c1-3-13-36(33,34)31-20-7-9-22(18(2)14-20)26-24(16-28)23-10-8-21(35-27-29-11-4-12-30-27)15-25(23)32(26)17-19-5-6-19;1-2-15-35(32,33)30-21-10-8-20(9-11-21)27-24(17-28)23-13-12-22(34-26-5-3-4-14-29-26)16-25(23)31(27)18-19-6-7-19;1-2-15-33(31,32)28-19-9-7-18(8-10-19)25-23(17-26)22-12-11-21(29-14-4-13-27-29)16-24(22)30(25)20-5-3-6-20;1-14(2)28-34(31,32)29-17-7-5-16(6-8-17)22-20(12-27)19-10-9-18(33-23(24,25)26)11-21(19)30(22)13-15-3-4-15;1-5-26-21-13-18(29-6-2)11-12-19(21)20(14-23)22(26)16-7-9-17(10-8-16)25-30(27,28)24-15(3)4;1-4-28-19-11-16(31-21(22,23)24)9-10-17(19)18(12-25)20(28)14-5-7-15(8-6-14)27-32(29,30)26-13(2)3/h4,7-12,14-15,19,31H,3,5-6,13,17H2,1-2H3;3-5,8-14,16,19,30H,2,6-7,15,18H2,1H3;4,7-14,16,20,28H,2-3,5-6,15H2,1H3;5-11,14-15,28-29H,3-4,13H2,1-2H3;7-13,15,24-25H,5-6H2,1-4H3;5-11,13,26-27H,4H2,1-3H3
InChIKeyKPHMXQUUYHGWHY-UHFFFAOYSA-N
XLogP30.95
TPSA588.07 Ų
H-Bond Donors9
H-Bond Acceptors34
Rotatable Bonds48
Heavy Atoms200
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002833.33
LogP ≤ 530.95
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1034

Analyze N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile with MolForge

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Related Compounds

CID 157153677
CID 157153677
N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]propane-1-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]-3-propan-2-ylurea;1-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]-3-propan-2-ylurea;N-[4-[3-cyano-1-cyclopropyl-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(2,2-difluoroethoxy)indol-2-yl]phenyl]carbamate
CID 157180987
N-[4-[3-cyano-1-cyclobutyl-6-(4-methoxy-3-pyridinyl)indol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(2-methylpyrazol-3-yl)indol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-(pyrimidin-2-ylamino)indol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-(2-fluoroethoxy)-2-[4-[(4-methyl-1,3-thiazol-2-yl)amino]phenyl]indole-3-carbonitrile
CID 157242210
1-cyclobutyl-2-[4-(ethylsulfamoylamino)phenyl]-6-(oxan-4-yloxy)indole-3-carbonitrile;1-cyclobutyl-2-[4-(methylsulfamoylamino)phenyl]-6-(oxan-4-yloxy)indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[1-(cyclopropylmethyl)-6-ethoxy-3-fluoroindol-2-yl]phenyl]carbamate;[(1R)-1-(4-fluorophenyl)ethyl] N-[4-(3-cyano-1-cyclobutyl-5-morpholin-4-ylindol-2-yl)phenyl]carbamate;[(1R)-1-(4-fluorophenyl)ethyl] N-[4-[3-cyano-1-cyclobutyl-6-[4-(1,2,4-triazol-1-yl)butoxy]indol-2-yl]phenyl]carbamate;[(1R)-1-(4-fluorophenyl)ethyl] N-[4-[3-cyano-1-cyclopropyl-6-(2-imidazol-1-ylethoxy)indol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-(3-cyano-1-cyclobutyl-5-morpholin-4-ylindol-2-yl)phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-cyclobutyl-6-[4-(1,2,4-triazol-1-yl)butoxy]indol-2-yl]phenyl]carbamate
CID 157267853
N-[4-[3-cyano-1-(cyclopropylmethyl)-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(4-methylpyrimidin-2-yl)oxyindol-2-yl]-3-methylphenyl]carbamate;1-(cyclopropylmethyl)-6-(2-methylsulfonylethoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-(cyclopropylmethyl)-6-(3-methylsulfonylpropoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate
CID 157344993
CID 157632056
CID 157632056
N-[3-cyano-2-(4-ethoxyphenyl)-1-ethylindol-6-yl]cyclopropanesulfonamide;N-[3-cyano-2-(4-ethoxyphenyl)-1-ethylindol-6-yl]ethanesulfonamide;1-[3-cyano-2-(4-ethoxyphenyl)-1-ethylindol-6-yl]-3-ethylurea;N-[3-cyano-2-(4-ethoxyphenyl)-1-ethylindol-6-yl]propane-1-sulfonamide;N-[4-[3-cyano-1-ethyl-6-(2-fluoroethoxy)indol-2-yl]phenyl]-N-methylcyclopropanesulfonamide;ethyl N-[3-cyano-2-(4-ethoxyphenyl)-1-ethylindol-6-yl]carbamate;1-ethyl-2-(4-propylsulfonylpiperazin-1-yl)-6-(trifluoromethyl)indole-3-carbonitrile
CID 157796223
6-(3-cyano-6-cyclobutyl-1-cyclopentylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-ethylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-cyclohexyl-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-cyclopropyl-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1,6-di(cyclobutyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide
CID 157878762
1-[4-[3-cyano-1-cyclobutyl-6-(1,3-dioxan-5-yloxy)indol-2-yl]phenyl]-3-propan-2-ylurea;1-[4-[3-cyano-1-(cyclopropylmethyl)-6-morpholin-4-ylindol-2-yl]phenyl]-3-cyclobutylurea;N-[4-(3-cyano-1-cyclopropyl-6-morpholin-4-ylindol-2-yl)phenyl]cyclopropanesulfonamide;1-cyclopropyl-6-(oxan-4-yloxy)-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;[(1R)-1-(4-fluorophenyl)ethyl] N-[4-[3-cyano-1-cyclobutyl-6-(1,3-dioxolan-4-ylmethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-[3-cyano-1-cyclobutyl-6-[(1-ethylimidazol-2-yl)methoxy]indol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)indol-2-yl]phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-(3-cyano-1-cyclobutyl-6-ethoxyindol-2-yl)phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]phenyl]carbamate
CID 158131561
6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide
CID 158191630
CID 158385604
CID 158385604
6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclopentyl-6-(difluoromethoxy)indol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propylindol-2-yl]-N-[(1S)-1-cyclopropylethyl]pyrimidine-5-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;molecular hydrogen
CID 158388907

Frequently Asked Questions

What is the IUPAC name of N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile?
The IUPAC name of N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile (CID 159201090) is N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile.
What is the SMILES notation for N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile?
The canonical SMILES for N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile is CC(C)NS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(OC(F)(F)F)cc3n2CC2CC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(-n4cccn4)cc3n2C2CCC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ccccn4)cc3n2CC2CC2)cc1.CCCS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2CC2CC2)c(C)c1.CCOc1ccc2c(C#N)c(-c3ccc(NS(=O)(=O)NC(C)C)cc3)n(CC)c2c1.CCn1c(-c2ccc(NS(=O)(=O)NC(C)C)cc2)c(C#N)c2ccc(OC(F)(F)F)cc21.
What is the InChIKey of N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile?
The InChIKey is KPHMXQUUYHGWHY-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H27N5O3S.C27H26N4O3S.C25H25N5O2S.C23H23F3N4O3S.C22H26N4O3S.C21H21F3N4O3S/c1-3-13-36(33,34)31-20-7-9-22(18(2)14-20)26-24(16-28)23-10-8-21(35-27-29-11-4-12-30-27)15-25(23)32(26)17-19-5-6-19;1-2-15-35(32,33)30-21-10-8-20(9-11-21)27-24(17-28)23-13-12-22(34-26-5-3-4-14-29-26)16-25(23)31(27)18-19-6-7-19;1-2-15-33(31,32)28-19-9-7-18(8-10-19)25-23(17-26)22-12-11-21(29-14-4-13-27-29)16-24(22)30(25)20-5-3-6-20;1-14(2)28-34(31,32)29-17-7-5-16(6-8-17)22-20(12-27)19-10-9-18(33-23(24,25)26)11-21(19)30(22)13-15-3-4-15;1-5-26-21-13-18(29-6-2)11-12-19(21)20(14-23)22(26)16-7-9-17(10-8-16)25-30(27,28)24-15(3)4;1-4-28-19-11-16(31-21(22,23)24)9-10-17(19)18(12-25)20(28)14-5-7-15(8-6-14)27-32(29,30)26-13(2)3/h4,7-12,14-15,19,31H,3,5-6,13,17H2,1-2H3;3-5,8-14,16,19,30H,2,6-7,15,18H2,1H3;4,7-14,16,20,28H,2-3,5-6,15H2,1H3;5-11,14-15,28-29H,3-4,13H2,1-2H3;7-13,15,24-25H,5-6H2,1-4H3;5-11,13,26-27H,4H2,1-3H3.
What are the key properties of N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile?
N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile has a molecular weight of 2833.33 g/mol, XLogP of 30.95, 48 rotatable bonds, 9 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(3-cyano-1-cyclobutyl-6-pyrazol-1-ylindol-2-yl)phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyridin-2-yloxyindol-2-yl]phenyl]propane-1-sulfonamide;N-[4-[3-cyano-1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]-3-methylphenyl]propane-1-sulfonamide;1-(cyclopropylmethyl)-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile;6-ethoxy-1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]indole-3-carbonitrile;1-ethyl-2-[4-(propan-2-ylsulfamoylamino)phenyl]-6-(trifluoromethoxy)indole-3-carbonitrile is sourced from PubChem (CID 159201090), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).