methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one

C157H157F3N40O7S6 — CID 159215836

About methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one

methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one (PubChem CID 159215836) has the molecular formula C157H157F3N40O7S6 and a molecular weight of 2965.65 g/mol. Its IUPAC name is methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 159215836
• Molecular Formula: C157H157F3N40O7S6
• Molecular Weight: 2965.65 g/mol
• Exact Mass: 2963.14
• IUPAC Name: methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one
• SMILES: C.Cc1cc(-c2ccsc2)ncc1-c1cc2cnc(Nc3ccc(C4CCNCC4)cc3)nc2n(-c2nccs2)c1=O.Cc1cc(-c2nccs2)cnc1-c1cc2cnc(Nc3ccc(C4=CCNCC4)cc3)nc2n(CC(F)(F)F)c1=O.Cc1cnc(-c2cscn2)nc1-c1cc2cnc(Nc3ccc(C4CCCNC4)cc3)nc2n(CC2CCOCC2)c1=O.Cc1nc(-c2cncs2)ccc1-c1cc2cnc(Nc3ccc(C4CCN(C)C4)cc3)nc2n(Cc2nccs2)c1=O.Cc1nc(C2CCCN2C)ncc1-c1cc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n(CC(=O)N2CCCC2)c1=O
• InChI: InChI=1S/C33H40N10O2.C32H34N8O2S.C31H28N8OS2.C31H27N7OS2.C29H24F3N7OS.CH4/c1-22-27(20-35-30(37-22)28-6-5-13-40(28)2)26-18-23-19-36-33(38-24-7-9-25(10-8-24)41-16-11-34-12-17-41)39-31(23)43(32(26)45)21-29(44)42-14-3-4-15-42;1-20-14-34-29(27-18-43-19-36-27)38-28(20)26-13-24-16-35-32(37-25-6-4-22(5-7-25)23-3-2-10-33-15-23)39-30(24)40(31(26)41)17-21-8-11-42-12-9-21;1-19-24(7-8-26(35-19)27-15-32-18-42-27)25-13-22-14-34-31(37-29(22)39(30(25)40)17-28-33-10-12-41-28)36-23-5-3-20(4-6-23)21-9-11-38(2)16-21;1-19-14-27(22-8-12-40-18-22)34-17-26(19)25-15-23-16-35-30(37-28(23)38(29(25)39)31-33-11-13-41-31)36-24-4-2-20(3-5-24)21-6-9-32-10-7-21;1-17-12-21(26-34-10-11-41-26)15-35-24(17)23-13-20-14-36-28(38-25(20)39(27(23)40)16-29(30,31)32)37-22-4-2-18(3-5-22)19-6-8-33-9-7-19;/h7-10,18-20,28,34H,3-6,11-17,21H2,1-2H3,(H,36,38,39);4-7,13-14,16,18-19,21,23,33H,2-3,8-12,15,17H2,1H3,(H,35,37,39);3-8,10,12-15,18,21H,9,11,16-17H2,1-2H3,(H,34,36,37);2-5,8,11-18,21,32H,6-7,9-10H2,1H3,(H,35,36,37);2-6,10-15,33H,7-9,16H2,1H3,(H,36,37,38);1H4
• InChIKey: KRAYVWCKDUKUCY-UHFFFAOYSA-N
• XLogP: 27.52
• TPSA: 541.11 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 52
• Rotatable Bonds: 33
• Heavy Atoms: 213
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2965.65
LogP ≤ 5	27.52
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	52

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one (CID 159215836) is methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one is C.Cc1cc(-c2ccsc2)ncc1-c1cc2cnc(Nc3ccc(C4CCNCC4)cc3)nc2n(-c2nccs2)c1=O.Cc1cc(-c2nccs2)cnc1-c1cc2cnc(Nc3ccc(C4=CCNCC4)cc3)nc2n(CC(F)(F)F)c1=O.Cc1cnc(-c2cscn2)nc1-c1cc2cnc(Nc3ccc(C4CCCNC4)cc3)nc2n(CC2CCOCC2)c1=O.Cc1nc(-c2cncs2)ccc1-c1cc2cnc(Nc3ccc(C4CCN(C)C4)cc3)nc2n(Cc2nccs2)c1=O.Cc1nc(C2CCCN2C)ncc1-c1cc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n(CC(=O)N2CCCC2)c1=O.

What is the InChIKey of methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is KRAYVWCKDUKUCY-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H40N10O2.C32H34N8O2S.C31H28N8OS2.C31H27N7OS2.C29H24F3N7OS.CH4/c1-22-27(20-35-30(37-22)28-6-5-13-40(28)2)26-18-23-19-36-33(38-24-7-9-25(10-8-24)41-16-11-34-12-17-41)39-31(23)43(32(26)45)21-29(44)42-14-3-4-15-42;1-20-14-34-29(27-18-43-19-36-27)38-28(20)26-13-24-16-35-32(37-25-6-4-22(5-7-25)23-3-2-10-33-15-23)39-30(24)40(31(26)41)17-21-8-11-42-12-9-21;1-19-24(7-8-26(35-19)27-15-32-18-42-27)25-13-22-14-34-31(37-29(22)39(30(25)40)17-28-33-10-12-41-28)36-23-5-3-20(4-6-23)21-9-11-38(2)16-21;1-19-14-27(22-8-12-40-18-22)34-17-26(19)25-15-23-16-35-30(37-28(23)38(29(25)39)31-33-11-13-41-31)36-24-4-2-20(3-5-24)21-6-9-32-10-7-21;1-17-12-21(26-34-10-11-41-26)15-35-24(17)23-13-20-14-36-28(38-25(20)39(27(23)40)16-29(30,31)32)37-22-4-2-18(3-5-22)19-6-8-33-9-7-19;/h7-10,18-20,28,34H,3-6,11-17,21H2,1-2H3,(H,36,38,39);4-7,13-14,16,18-19,21,23,33H,2-3,8-12,15,17H2,1H3,(H,35,37,39);3-8,10,12-15,18,21H,9,11,16-17H2,1-2H3,(H,34,36,37);2-5,8,11-18,21,32H,6-7,9-10H2,1H3,(H,35,36,37);2-6,10-15,33H,7-9,16H2,1H3,(H,36,37,38);1H4.

What are the key properties of methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one?

methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 2965.65 g/mol, XLogP of 27.52, 33 rotatable bonds, 9 hydrogen bond donors, and 52 hydrogen bond acceptors.

Where does this data come from?

All data for methane;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)pyrimidin-5-yl]-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpyrrolidin-3-yl)anilino]-6-[2-methyl-6-(1,3-thiazol-5-yl)-3-pyridinyl]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3-thiazol-2-yl)-2-pyridinyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1,3-thiazol-4-yl)pyrimidin-4-yl]-8-(oxan-4-ylmethyl)-2-(4-piperidin-3-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-6-thiophen-3-yl-3-pyridinyl)-2-(4-piperidin-4-ylanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 159215836), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).