6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)

C131H111Cl6F16N27O12S6 — CID 159245520

About 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)

6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide) (PubChem CID 159245520) has the molecular formula C131H111Cl6F16N27O12S6 and a molecular weight of 2964.59 g/mol. Its IUPAC name is 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide).

Molecular Properties

• Compound Name: 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)
• PubChem CID: 159245520
• Molecular Formula: C131H111Cl6F16N27O12S6
• Molecular Weight: 2964.59 g/mol
• Exact Mass: 2959.51
• IUPAC Name: 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)
• SMILES: C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2-c2ccccn2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2-c2ccccn2)nc1)C(F)(F)F.Cc1cc2c(cc1Cl)c(C#N)c(-c1ccc(S(=O)(=O)NC(CF)CF)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C#N)c(-c1ncc(S(=O)(=O)NC(CF)CF)cn1)n2C1CCC1
• InChI: InChI=1S/2C22H15ClF3N5O2S.2C22H20ClF3N4O2S.C22H21ClF2N4O2S.C21H20ClF2N5O2S/c2*1-13(22(24,25)26)30-34(32,33)15-6-7-18(29-12-15)21-17(11-27)16-10-14(23)5-8-19(16)31(21)20-4-2-3-9-28-20;2*1-12-8-20-16(9-18(12)23)17(10-27)21(30(20)14-4-3-5-14)19-7-6-15(11-28-19)33(31,32)29-13(2)22(24,25)26;1-13-7-21-17(8-19(13)23)18(11-26)22(29(21)15-3-2-4-15)20-6-5-16(12-27-20)32(30,31)28-14(9-24)10-25;1-12-5-19-16(6-18(12)22)17(9-25)20(29(19)14-3-2-4-14)21-26-10-15(11-27-21)32(30,31)28-13(7-23)8-24/h2*2-10,12-13,30H,1H3;2*6-9,11,13-14,29H,3-5H2,1-2H3;5-8,12,14-15,28H,2-4,9-10H2,1H3;5-6,10-11,13-14,28H,2-4,7-8H2,1H3/t4*13-;;/m0010../s1
• InChIKey: KUQBMEYELOKTJH-FRUZGCDCSA-N
• XLogP: 29.76
• TPSA: 565.35 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 33
• Rotatable Bonds: 34
• Heavy Atoms: 198
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2964.59
LogP ≤ 5	29.76
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)?

The IUPAC name of 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide) (CID 159245520) is 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide).

What is the SMILES notation for 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)?

The canonical SMILES for 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide) is C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2-c2ccccn2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2-c2ccccn2)nc1)C(F)(F)F.Cc1cc2c(cc1Cl)c(C#N)c(-c1ccc(S(=O)(=O)NC(CF)CF)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C#N)c(-c1ncc(S(=O)(=O)NC(CF)CF)cn1)n2C1CCC1.

What is the InChIKey of 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)?

The InChIKey is KUQBMEYELOKTJH-FRUZGCDCSA-N. The full InChI is InChI=1S/2C22H15ClF3N5O2S.2C22H20ClF3N4O2S.C22H21ClF2N4O2S.C21H20ClF2N5O2S/c2*1-13(22(24,25)26)30-34(32,33)15-6-7-18(29-12-15)21-17(11-27)16-10-14(23)5-8-19(16)31(21)20-4-2-3-9-28-20;2*1-12-8-20-16(9-18(12)23)17(10-27)21(30(20)14-4-3-5-14)19-7-6-15(11-28-19)33(31,32)29-13(2)22(24,25)26;1-13-7-21-17(8-19(13)23)18(11-26)22(29(21)15-3-2-4-15)20-6-5-16(12-27-20)32(30,31)28-14(9-24)10-25;1-12-5-19-16(6-18(12)22)17(9-25)20(29(19)14-3-2-4-14)21-26-10-15(11-27-21)32(30,31)28-13(7-23)8-24/h2*2-10,12-13,30H,1H3;2*6-9,11,13-14,29H,3-5H2,1-2H3;5-8,12,14-15,28H,2-4,9-10H2,1H3;5-6,10-11,13-14,28H,2-4,7-8H2,1H3/t4*13-;;/m0010../s1.

What are the key properties of 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide)?

6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide) has a molecular weight of 2964.59 g/mol, XLogP of 29.76, 34 rotatable bonds, 6 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclobutyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;bis(6-(5-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide) is sourced from PubChem (CID 159245520), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).