5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

C135H135Cl3F21N25O18S6 — CID 158021728

About 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (PubChem CID 158021728) has the molecular formula C135H135Cl3F21N25O18S6 and a molecular weight of 3093.44 g/mol. Its IUPAC name is 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

Molecular Properties

• Compound Name: 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• PubChem CID: 158021728
• Molecular Formula: C135H135Cl3F21N25O18S6
• Molecular Weight: 3093.44 g/mol
• Exact Mass: 3089.75
• IUPAC Name: 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• SMILES: C[C@H](NS(=O)(=O)c1ccc(-c2c(C(N)=O)c3cc(F)c(C4CC4)cc3n2C2CCC2)nc1)C(F)(F)F.Cc1cc2c(cc1Cl)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C(N)=O)c(-c1ncc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1
• InChI: InChI=1S/2C24H24F4N4O3S.2C22H22ClF3N4O3S.C22H22F4N4O3S.C21H21ClF3N5O3S/c1-12(24(26,27)28)31-36(34,35)15-7-8-19(30-11-15)22-21(23(29)33)17-9-18(25)16(13-5-6-13)10-20(17)32(22)14-3-2-4-14;1-13-10-19-16(11-17(13)25)20(22(29)33)21(32(19)14-4-2-3-5-14)18-7-6-15(12-30-18)36(34,35)31-23(8-9-23)24(26,27)28;3*1-11-8-18-15(9-16(11)23)19(21(27)31)20(30(18)13-4-3-5-13)17-7-6-14(10-28-17)34(32,33)29-12(2)22(24,25)26;1-10-6-16-14(7-15(10)22)17(19(26)31)18(30(16)12-4-3-5-12)20-27-8-13(9-28-20)34(32,33)29-11(2)21(23,24)25/h7-14,31H,2-6H2,1H3,(H2,29,33);6-7,10-12,14,31H,2-5,8-9H2,1H3,(H2,29,33);3*6-10,12-13,29H,3-5H2,1-2H3,(H2,27,31);6-9,11-12,29H,3-5H2,1-2H3,(H2,26,31)/t12-;;3*12-;11-/m0.1010/s1
• InChIKey: FGDITCZBJZQKHK-AJDZXJIISA-N
• XLogP: 27.26
• TPSA: 655.37 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 31
• Rotatable Bonds: 37
• Heavy Atoms: 208
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3093.44
LogP ≤ 5	27.26
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The IUPAC name of 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (CID 158021728) is 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

What is the SMILES notation for 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The canonical SMILES for 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is C[C@H](NS(=O)(=O)c1ccc(-c2c(C(N)=O)c3cc(F)c(C4CC4)cc3n2C2CCC2)nc1)C(F)(F)F.Cc1cc2c(cc1Cl)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1Cl)c(C(N)=O)c(-c1ncc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1.

What is the InChIKey of 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The InChIKey is FGDITCZBJZQKHK-AJDZXJIISA-N. The full InChI is InChI=1S/2C24H24F4N4O3S.2C22H22ClF3N4O3S.C22H22F4N4O3S.C21H21ClF3N5O3S/c1-12(24(26,27)28)31-36(34,35)15-7-8-19(30-11-15)22-21(23(29)33)17-9-18(25)16(13-5-6-13)10-20(17)32(22)14-3-2-4-14;1-13-10-19-16(11-17(13)25)20(22(29)33)21(32(19)14-4-2-3-5-14)18-7-6-15(12-30-18)36(34,35)31-23(8-9-23)24(26,27)28;3*1-11-8-18-15(9-16(11)23)19(21(27)31)20(30(18)13-4-3-5-13)17-7-6-14(10-28-17)34(32,33)29-12(2)22(24,25)26;1-10-6-16-14(7-15(10)22)17(19(26)31)18(30(16)12-4-3-5-12)20-27-8-13(9-28-20)34(32,33)29-11(2)21(23,24)25/h7-14,31H,2-6H2,1H3,(H2,29,33);6-7,10-12,14,31H,2-5,8-9H2,1H3,(H2,29,33);3*6-10,12-13,29H,3-5H2,1-2H3,(H2,27,31);6-9,11-12,29H,3-5H2,1-2H3,(H2,26,31)/t12-;;3*12-;11-/m0.1010/s1.

What are the key properties of 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide has a molecular weight of 3093.44 g/mol, XLogP of 27.26, 37 rotatable bonds, 12 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-chloro-1-cyclobutyl-6-methyl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrimidin-2-yl]indole-3-carboxamide;1-cyclobutyl-6-cyclopropyl-5-fluoro-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-5-fluoro-6-methyl-2-[5-[[(2R)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-5-fluoro-6-methyl-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is sourced from PubChem (CID 158021728), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).