1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide

C103H104Cl4F4N36O5 — CID 159291684

About 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide

1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide (PubChem CID 159291684) has the molecular formula C103H104Cl4F4N36O5 and a molecular weight of 2144.02 g/mol. Its IUPAC name is 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide.

Molecular Properties

• Compound Name: 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide
• PubChem CID: 159291684
• Molecular Formula: C103H104Cl4F4N36O5
• Molecular Weight: 2144.02 g/mol
• Exact Mass: 2140.77
• IUPAC Name: 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide
• SMILES: CC(=O)N1C(C)CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)CC1c1cn[nH]c1.CC(=O)N1C(C)CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)CC1c1cn[nH]c1C.COc1cc(-c2cnc3ccc(Cl)cn23)nc(N2C[C@H](C)C[C@@H](c3cn[nH]c3)C2)n1.COc1cc(-c2cnc3ccc(Cl)cn23)nc(N2C[C@H](C)C[C@H](c3cn[nH]c3)C2)n1.NC(=O)[C@H]1CCCN(c2nc(-c3cnc4ccc(C(F)(F)F)cn34)ncc2F)C1
• InChI: InChI=1S/C22H23ClN8O.C21H21ClN8O.2C21H22ClN7O.C18H16F4N6O/c1-13-10-29(12-19(31(13)15(3)32)17-8-26-28-14(17)2)21-6-7-24-22(27-21)18-9-25-20-5-4-16(23)11-30(18)20;1-13-10-28(12-18(30(13)14(2)31)15-7-25-26-8-15)20-5-6-23-21(27-20)17-9-24-19-4-3-16(22)11-29(17)19;2*1-13-5-14(15-7-24-25-8-15)11-28(10-13)21-26-17(6-20(27-21)30-2)18-9-23-19-4-3-16(22)12-29(18)19;19-12-6-25-16(26-17(12)27-5-1-2-10(8-27)15(23)29)13-7-24-14-4-3-11(9-28(13)14)18(20,21)22/h4-9,11,13,19H,10,12H2,1-3H3,(H,26,28);3-9,11,13,18H,10,12H2,1-2H3,(H,25,26);2*3-4,6-9,12-14H,5,10-11H2,1-2H3,(H,24,25);3-4,6-7,9-10H,1-2,5,8H2,(H2,23,29)/t;;13-,14+;13-,14-;10-/m..110/s1
• InChIKey: LAFAUVJMUVYEAE-OBGCOXKLSA-N
• XLogP: 16.50
• TPSA: 448.49 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 34
• Rotatable Bonds: 17
• Heavy Atoms: 152
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2144.02
LogP ≤ 5	16.50
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide?

The IUPAC name of 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide (CID 159291684) is 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide.

What is the SMILES notation for 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide?

The canonical SMILES for 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide is CC(=O)N1C(C)CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)CC1c1cn[nH]c1.CC(=O)N1C(C)CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)CC1c1cn[nH]c1C.COc1cc(-c2cnc3ccc(Cl)cn23)nc(N2C[C@H](C)C[C@@H](c3cn[nH]c3)C2)n1.COc1cc(-c2cnc3ccc(Cl)cn23)nc(N2C[C@H](C)C[C@H](c3cn[nH]c3)C2)n1.NC(=O)[C@H]1CCCN(c2nc(-c3cnc4ccc(C(F)(F)F)cn34)ncc2F)C1.

What is the InChIKey of 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide?

The InChIKey is LAFAUVJMUVYEAE-OBGCOXKLSA-N. The full InChI is InChI=1S/C22H23ClN8O.C21H21ClN8O.2C21H22ClN7O.C18H16F4N6O/c1-13-10-29(12-19(31(13)15(3)32)17-8-26-28-14(17)2)21-6-7-24-22(27-21)18-9-25-20-5-4-16(23)11-30(18)20;1-13-10-28(12-18(30(13)14(2)31)15-7-25-26-8-15)20-5-6-23-21(27-20)17-9-24-19-4-3-16(22)11-29(17)19;2*1-13-5-14(15-7-24-25-8-15)11-28(10-13)21-26-17(6-20(27-21)30-2)18-9-23-19-4-3-16(22)12-29(18)19;19-12-6-25-16(26-17(12)27-5-1-2-10(8-27)15(23)29)13-7-24-14-4-3-11(9-28(13)14)18(20,21)22/h4-9,11,13,19H,10,12H2,1-3H3,(H,26,28);3-9,11,13,18H,10,12H2,1-2H3,(H,25,26);2*3-4,6-9,12-14H,5,10-11H2,1-2H3,(H,24,25);3-4,6-7,9-10H,1-2,5,8H2,(H2,23,29)/t;;13-,14+;13-,14-;10-/m..110/s1.

What are the key properties of 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide?

1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide has a molecular weight of 2144.02 g/mol, XLogP of 16.50, 17 rotatable bonds, 5 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)piperazin-1-yl]ethanone;1-[4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-methyl-6-(1H-pyrazol-4-yl)piperazin-1-yl]ethanone;6-chloro-3-[6-methoxy-2-[(3R,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[6-methoxy-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;(3S)-1-[5-fluoro-2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide is sourced from PubChem (CID 159291684), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).