5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane

C113H86ClF20N15O11S5 — CID 159426952

About 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane

5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane (PubChem CID 159426952) has the molecular formula C113H86ClF20N15O11S5 and a molecular weight of 2405.77 g/mol. Its IUPAC name is 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane.

Molecular Properties

• Compound Name: 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane
• PubChem CID: 159426952
• Molecular Formula: C113H86ClF20N15O11S5
• Molecular Weight: 2405.77 g/mol
• Exact Mass: 2403.46
• IUPAC Name: 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane
• SMILES: C.Cc1nc(C)c(-c2nc(CC(=O)c3c(F)cccc3F)sc2-c2cccc(C(F)(F)F)c2)o1.Cc1ncc(-c2nc(NC(=O)c3cnc(OCO)c(Cl)c3)sc2N2CCN(C3CCCCC3)CC2)o1.Cc1ncoc1-c1nc(CC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1.Cn1cncc1-c1nc(CC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1.O=C(Cc1nc(-c2cnco2)c(-c2cccc(C(F)(F)F)c2)s1)c1c(F)cccc1F
• InChI: InChI=1S/C24H29ClN6O4S.C23H15F5N2O2S.C22H14F5N3OS.C22H13F5N2O2S.C21H11F5N2O2S.CH4/c1-15-26-13-19(35-15)20-23(31-9-7-30(8-10-31)17-5-3-2-4-6-17)36-24(28-20)29-21(33)16-11-18(25)22(27-12-16)34-14-32;1-11-21(32-12(2)29-11)20-22(13-5-3-6-14(9-13)23(26,27)28)33-18(30-20)10-17(31)19-15(24)7-4-8-16(19)25;1-30-11-28-10-16(30)20-21(12-4-2-5-13(8-12)22(25,26)27)32-18(29-20)9-17(31)19-14(23)6-3-7-15(19)24;1-11-20(31-10-28-11)19-21(12-4-2-5-13(8-12)22(25,26)27)32-17(29-19)9-16(30)18-14(23)6-3-7-15(18)24;22-13-5-2-6-14(23)18(13)15(29)8-17-28-19(16-9-27-10-30-16)20(31-17)11-3-1-4-12(7-11)21(24,25)26;/h11-13,17,32H,2-10,14H2,1H3,(H,28,29,33);3-9H,10H2,1-2H3;2-8,10-11H,9H2,1H3;2-8,10H,9H2,1H3;1-7,9-10H,8H2;1H4
• InChIKey: LQMFRIQWYFUDSE-UHFFFAOYSA-N
• XLogP: 30.25
• TPSA: 332.60 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 30
• Rotatable Bonds: 27
• Heavy Atoms: 165
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2405.77
LogP ≤ 5	30.25
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'het-C-het_not_in_ring', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane?

The IUPAC name of 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane (CID 159426952) is 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane.

What is the SMILES notation for 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane?

The canonical SMILES for 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane is C.Cc1nc(C)c(-c2nc(CC(=O)c3c(F)cccc3F)sc2-c2cccc(C(F)(F)F)c2)o1.Cc1ncc(-c2nc(NC(=O)c3cnc(OCO)c(Cl)c3)sc2N2CCN(C3CCCCC3)CC2)o1.Cc1ncoc1-c1nc(CC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1.Cn1cncc1-c1nc(CC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1.O=C(Cc1nc(-c2cnco2)c(-c2cccc(C(F)(F)F)c2)s1)c1c(F)cccc1F.

What is the InChIKey of 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane?

The InChIKey is LQMFRIQWYFUDSE-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H29ClN6O4S.C23H15F5N2O2S.C22H14F5N3OS.C22H13F5N2O2S.C21H11F5N2O2S.CH4/c1-15-26-13-19(35-15)20-23(31-9-7-30(8-10-31)17-5-3-2-4-6-17)36-24(28-20)29-21(33)16-11-18(25)22(27-12-16)34-14-32;1-11-21(32-12(2)29-11)20-22(13-5-3-6-14(9-13)23(26,27)28)33-18(30-20)10-17(31)19-15(24)7-4-8-16(19)25;1-30-11-28-10-16(30)20-21(12-4-2-5-13(8-12)22(25,26)27)32-18(29-20)9-17(31)19-14(23)6-3-7-15(19)24;1-11-20(31-10-28-11)19-21(12-4-2-5-13(8-12)22(25,26)27)32-17(29-19)9-16(30)18-14(23)6-3-7-15(18)24;22-13-5-2-6-14(23)18(13)15(29)8-17-28-19(16-9-27-10-30-16)20(31-17)11-3-1-4-12(7-11)21(24,25)26;/h11-13,17,32H,2-10,14H2,1H3,(H,28,29,33);3-9H,10H2,1-2H3;2-8,10-11H,9H2,1H3;2-8,10H,9H2,1H3;1-7,9-10H,8H2;1H4.

What are the key properties of 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane?

5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane has a molecular weight of 2405.77 g/mol, XLogP of 30.25, 27 rotatable bonds, 2 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 5-chloro-N-[5-(4-cyclohexylpiperazin-1-yl)-4-(2-methyl-1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-6-(hydroxymethoxy)pyridine-3-carboxamide;1-(2,6-difluorophenyl)-2-[4-(2,4-dimethyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;methane is sourced from PubChem (CID 159426952), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).