6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

C136H125Cl2F15N26O12S6 — CID 159427871

About 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (PubChem CID 159427871) has the molecular formula C136H125Cl2F15N26O12S6 and a molecular weight of 2863.94 g/mol. Its IUPAC name is 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• PubChem CID: 159427871
• Molecular Formula: C136H125Cl2F15N26O12S6
• Molecular Weight: 2863.94 g/mol
• Exact Mass: 2860.74
• IUPAC Name: 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• SMILES: C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2-c2ccccn2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2-c2ccccn2)nc1)C1CC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C(C)C.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCCC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCCCC1
• InChI: InChI=1S/C24H20ClN5O2S.C24H25F3N4O2S.C23H23F3N4O2S.C22H15ClF3N5O2S.C22H21F3N4O2S.C21H21F3N4O2S/c1-15(16-5-6-16)29-33(31,32)18-8-10-21(28-14-18)24-20(13-26)19-9-7-17(25)12-22(19)30(24)23-4-2-3-11-27-23;1-15-8-11-22-19(12-15)20(13-28)23(31(22)17-6-4-3-5-7-17)21-10-9-18(14-29-21)34(32,33)30-16(2)24(25,26)27;1-14-7-10-21-18(11-14)19(12-27)22(30(21)16-5-3-4-6-16)20-9-8-17(13-28-20)33(31,32)29-15(2)23(24,25)26;1-13(22(24,25)26)30-34(32,33)15-6-8-18(29-12-15)21-17(11-27)16-7-5-14(23)10-19(16)31(21)20-4-2-3-9-28-20;1-13-6-9-20-17(10-13)18(11-26)21(29(20)15-4-3-5-15)19-8-7-16(12-27-19)32(30,31)28-14(2)22(23,24)25;1-12(2)28-19-8-5-13(3)9-16(19)17(10-25)20(28)18-7-6-15(11-26-18)31(29,30)27-14(4)21(22,23)24/h2-4,7-12,14-16,29H,5-6H2,1H3;8-12,14,16-17,30H,3-7H2,1-2H3;7-11,13,15-16,29H,3-6H2,1-2H3;2-10,12-13,30H,1H3;6-10,12,14-15,28H,3-5H2,1-2H3;5-9,11-12,14,27H,1-4H3/t15-;16-;15-;13-;2*14-/m011111/s1
• InChIKey: LQPGFWLNQWJAMK-BKANDBMHSA-N
• XLogP: 29.91
• TPSA: 552.46 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 32
• Rotatable Bonds: 31
• Heavy Atoms: 197
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2863.94
LogP ≤ 5	29.91
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The IUPAC name of 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (CID 159427871) is 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

What is the SMILES notation for 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The canonical SMILES for 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2-c2ccccn2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2-c2ccccn2)nc1)C1CC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C(C)C.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCCC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCCCC1.

What is the InChIKey of 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The InChIKey is LQPGFWLNQWJAMK-BKANDBMHSA-N. The full InChI is InChI=1S/C24H20ClN5O2S.C24H25F3N4O2S.C23H23F3N4O2S.C22H15ClF3N5O2S.C22H21F3N4O2S.C21H21F3N4O2S/c1-15(16-5-6-16)29-33(31,32)18-8-10-21(28-14-18)24-20(13-26)19-9-7-17(25)12-22(19)30(24)23-4-2-3-11-27-23;1-15-8-11-22-19(12-15)20(13-28)23(31(22)17-6-4-3-5-7-17)21-10-9-18(14-29-21)34(32,33)30-16(2)24(25,26)27;1-14-7-10-21-18(11-14)19(12-27)22(30(21)16-5-3-4-6-16)20-9-8-17(13-28-20)33(31,32)29-15(2)23(24,25)26;1-13(22(24,25)26)30-34(32,33)15-6-8-18(29-12-15)21-17(11-27)16-7-5-14(23)10-19(16)31(21)20-4-2-3-9-28-20;1-13-6-9-20-17(10-13)18(11-26)21(29(20)15-4-3-5-15)19-8-7-16(12-27-19)32(30,31)28-14(2)22(23,24)25;1-12(2)28-19-8-5-13(3)9-16(19)17(10-25)20(28)18-7-6-15(11-26-18)31(29,30)27-14(4)21(22,23)24/h2-4,7-12,14-16,29H,5-6H2,1H3;8-12,14,16-17,30H,3-7H2,1-2H3;7-11,13,15-16,29H,3-6H2,1-2H3;2-10,12-13,30H,1H3;6-10,12,14-15,28H,3-5H2,1-2H3;5-9,11-12,14,27H,1-4H3/t15-;16-;15-;13-;2*14-/m011111/s1.

What are the key properties of 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide has a molecular weight of 2863.94 g/mol, XLogP of 29.91, 31 rotatable bonds, 6 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-pyridin-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-propan-2-ylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is sourced from PubChem (CID 159427871), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).