5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide

C108H86F10N16O17 — CID 159520462

IUPAC5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide
SMILESCOc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4ccc(C(F)(F)F)cc4)c3F)c2cc1OC.COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4cccc(C)c4)c3F)c2cc1OC.COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4ccccc4C(F)(F)F)c3F)c2cc1OC.COc1ccc(NC(=O)n2c(C)cc3c(F)c(Oc4ncnc5cc(OC)c(OC)cc45)ccc32)cc1
InChIInChI=1S/2C27H20F4N4O4.C27H23FN4O5.C27H23FN4O4/c1-14-10-18-20(35(14)26(36)34-16-6-4-15(5-7-16)27(29,30)31)8-9-21(24(18)28)39-25-17-11-22(37-2)23(38-3)12-19(17)32-13-33-25;1-14-10-16-20(35(14)26(36)34-18-7-5-4-6-17(18)27(29,30)31)8-9-21(24(16)28)39-25-15-11-22(37-2)23(38-3)12-19(15)32-13-33-25;1-15-11-19-21(32(15)27(33)31-16-5-7-17(34-2)8-6-16)9-10-22(25(19)28)37-26-18-12-23(35-3)24(36-4)13-20(18)29-14-30-26;1-15-6-5-7-17(10-15)31-27(33)32-16(2)11-19-21(32)8-9-22(25(19)28)36-26-18-12-23(34-3)24(35-4)13-20(18)29-14-30-26/h2*4-13H,1-3H3,(H,34,36);5-14H,1-4H3,(H,31,33);5-14H,1-4H3,(H,31,33)
InChIKeyMBSSLYUKRGCFJF-UHFFFAOYSA-N
MW2069.95 g/mol
LogP26.04
Rot. Bonds21

About 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide

5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide (PubChem CID 159520462) has the molecular formula C108H86F10N16O17 and a molecular weight of 2069.95 g/mol. Its IUPAC name is 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide.

Molecular Properties

Compound Name5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide
PubChem CID159520462
Molecular FormulaC108H86F10N16O17
Molecular Weight2069.95 g/mol
Exact Mass2068.62
IUPAC Name5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide
SMILESCOc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4ccc(C(F)(F)F)cc4)c3F)c2cc1OC.COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4cccc(C)c4)c3F)c2cc1OC.COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4ccccc4C(F)(F)F)c3F)c2cc1OC.COc1ccc(NC(=O)n2c(C)cc3c(F)c(Oc4ncnc5cc(OC)c(OC)cc45)ccc32)cc1
InChIInChI=1S/2C27H20F4N4O4.C27H23FN4O5.C27H23FN4O4/c1-14-10-18-20(35(14)26(36)34-16-6-4-15(5-7-16)27(29,30)31)8-9-21(24(18)28)39-25-17-11-22(37-2)23(38-3)12-19(17)32-13-33-25;1-14-10-16-20(35(14)26(36)34-18-7-5-4-6-17(18)27(29,30)31)8-9-21(24(16)28)39-25-15-11-22(37-2)23(38-3)12-19(15)32-13-33-25;1-15-11-19-21(32(15)27(33)31-16-5-7-17(34-2)8-6-16)9-10-22(25(19)28)37-26-18-12-23(35-3)24(36-4)13-20(18)29-14-30-26;1-15-6-5-7-17(10-15)31-27(33)32-16(2)11-19-21(32)8-9-22(25(19)28)36-26-18-12-23(34-3)24(35-4)13-20(18)29-14-30-26/h2*4-13H,1-3H3,(H,34,36);5-14H,1-4H3,(H,31,33);5-14H,1-4H3,(H,31,33)
InChIKeyMBSSLYUKRGCFJF-UHFFFAOYSA-N
XLogP26.04
TPSA359.23 Ų
H-Bond Donors4
H-Bond Acceptors29
Rotatable Bonds21
Heavy Atoms151
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002069.95
LogP ≤ 526.04
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1029

Analyze 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide with MolForge

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Related Compounds

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Frequently Asked Questions

What is the IUPAC name of 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide?
The IUPAC name of 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide (CID 159520462) is 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide.
What is the SMILES notation for 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide?
The canonical SMILES for 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide is COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4ccc(C(F)(F)F)cc4)c3F)c2cc1OC.COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4cccc(C)c4)c3F)c2cc1OC.COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Nc4ccccc4C(F)(F)F)c3F)c2cc1OC.COc1ccc(NC(=O)n2c(C)cc3c(F)c(Oc4ncnc5cc(OC)c(OC)cc45)ccc32)cc1.
What is the InChIKey of 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide?
The InChIKey is MBSSLYUKRGCFJF-UHFFFAOYSA-N. The full InChI is InChI=1S/2C27H20F4N4O4.C27H23FN4O5.C27H23FN4O4/c1-14-10-18-20(35(14)26(36)34-16-6-4-15(5-7-16)27(29,30)31)8-9-21(24(18)28)39-25-17-11-22(37-2)23(38-3)12-19(17)32-13-33-25;1-14-10-16-20(35(14)26(36)34-18-7-5-4-6-17(18)27(29,30)31)8-9-21(24(16)28)39-25-15-11-22(37-2)23(38-3)12-19(15)32-13-33-25;1-15-11-19-21(32(15)27(33)31-16-5-7-17(34-2)8-6-16)9-10-22(25(19)28)37-26-18-12-23(35-3)24(36-4)13-20(18)29-14-30-26;1-15-6-5-7-17(10-15)31-27(33)32-16(2)11-19-21(32)8-9-22(25(19)28)36-26-18-12-23(34-3)24(35-4)13-20(18)29-14-30-26/h2*4-13H,1-3H3,(H,34,36);5-14H,1-4H3,(H,31,33);5-14H,1-4H3,(H,31,33).
What are the key properties of 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide?
5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide has a molecular weight of 2069.95 g/mol, XLogP of 26.04, 21 rotatable bonds, 4 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-N-(4-methoxyphenyl)-2-methylindole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-(3-methylphenyl)indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[2-(trifluoromethyl)phenyl]indole-1-carboxamide;5-(6,7-dimethoxyquinazolin-4-yl)oxy-4-fluoro-2-methyl-N-[4-(trifluoromethyl)phenyl]indole-1-carboxamide is sourced from PubChem (CID 159520462), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).