6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide

C139H144F10N24O15S6 — CID 159543010

About 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide

6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide (PubChem CID 159543010) has the molecular formula C139H144F10N24O15S6 and a molecular weight of 2773.22 g/mol. Its IUPAC name is 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide
• PubChem CID: 159543010
• Molecular Formula: C139H144F10N24O15S6
• Molecular Weight: 2773.22 g/mol
• Exact Mass: 2770.94
• IUPAC Name: 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide
• SMILES: COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCC3)c2c1.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C3CCC3)c2c1.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn3)n(C3CCC3)c2c1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2c1F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C(C)C)c2c1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C3CCCC3)c2c1
• InChI: InChI=1S/C25H28N4O2S.C24H26N4O3S.C23H22F4N4O2S.C23H26N4O2S.2C22H21F3N4O3S/c1-16-7-11-21-22(14-26)25(29(24(21)13-16)19-5-3-4-6-19)23-12-10-20(15-27-23)32(30,31)28-17(2)18-8-9-18;1-15(16-6-7-16)27-32(29,30)19-9-11-22(26-14-19)24-21(13-25)20-10-8-18(31-2)12-23(20)28(24)17-4-3-5-17;1-13-7-9-17-18(11-28)21(31(22(17)20(13)24)15-5-3-4-6-15)19-10-8-16(12-29-19)34(32,33)30-14(2)23(25,26)27;1-14(2)27-22-11-15(3)5-9-19(22)20(12-24)23(27)21-10-8-18(13-25-21)30(28,29)26-16(4)17-6-7-17;2*1-13(22(23,24)25)28-33(30,31)16-7-9-19(27-12-16)21-18(11-26)17-8-6-15(32-2)10-20(17)29(21)14-4-3-5-14/h7,10-13,15,17-19,28H,3-6,8-9H2,1-2H3;8-12,14-17,27H,3-7H2,1-2H3;7-10,12,14-15,30H,3-6H2,1-2H3;5,8-11,13-14,16-17,26H,6-7H2,1-4H3;2*6-10,12-14,28H,3-5H2,1-2H3/t17-;15-;14-;16-;2*13-/m000010/s1
• InChIKey: MELKNIPSCYNTCI-KEZBHBGLSA-N
• XLogP: 28.44
• TPSA: 554.37 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 33
• Rotatable Bonds: 36
• Heavy Atoms: 194
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2773.22
LogP ≤ 5	28.44
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

The IUPAC name of 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide (CID 159543010) is 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide.

What is the SMILES notation for 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

The canonical SMILES for 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide is COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCC3)c2c1.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C3CCC3)c2c1.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn3)n(C3CCC3)c2c1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2c1F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C(C)C)c2c1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C4CC4)cn3)n(C3CCCC3)c2c1.

What is the InChIKey of 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

The InChIKey is MELKNIPSCYNTCI-KEZBHBGLSA-N. The full InChI is InChI=1S/C25H28N4O2S.C24H26N4O3S.C23H22F4N4O2S.C23H26N4O2S.2C22H21F3N4O3S/c1-16-7-11-21-22(14-26)25(29(24(21)13-16)19-5-3-4-6-19)23-12-10-20(15-27-23)32(30,31)28-17(2)18-8-9-18;1-15(16-6-7-16)27-32(29,30)19-9-11-22(26-14-19)24-21(13-25)20-10-8-18(31-2)12-23(20)28(24)17-4-3-5-17;1-13-7-9-17-18(11-28)21(31(22(17)20(13)24)15-5-3-4-6-15)19-10-8-16(12-29-19)34(32,33)30-14(2)23(25,26)27;1-14(2)27-22-11-15(3)5-9-19(22)20(12-24)23(27)21-10-8-18(13-25-21)30(28,29)26-16(4)17-6-7-17;2*1-13(22(23,24)25)28-33(30,31)16-7-9-19(27-12-16)21-18(11-26)17-8-6-15(32-2)10-20(17)29(21)14-4-3-5-14/h7,10-13,15,17-19,28H,3-6,8-9H2,1-2H3;8-12,14-17,27H,3-7H2,1-2H3;7-10,12,14-15,30H,3-6H2,1-2H3;5,8-11,13-14,16-17,26H,6-7H2,1-4H3;2*6-10,12-14,28H,3-5H2,1-2H3/t17-;15-;14-;16-;2*13-/m000010/s1.

What are the key properties of 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide?

6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide has a molecular weight of 2773.22 g/mol, XLogP of 28.44, 36 rotatable bonds, 6 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-methoxyindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoro-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-propan-2-ylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide is sourced from PubChem (CID 159543010), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).