1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea

C270H327Cl2N43O43 — CID 159770164

IUPAC1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea
SMILESCCN(CCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1Cl)c1cccc(C)c1.CCN(CCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1OC)c1cccc(C)c1.CCN(CCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC)c1cccc(C)c1.COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NCCN(C(C)C)C(C)C.COc1cc2nccc(Oc3cc(C)c(NC(=O)NCCN(C(C)C)C(C)C)cc3C)c2cc1OC.COc1cc2nccc(Oc3cc(C)c(NC(=O)NCCN4CCCCC4)cc3C)c2cc1OC.COc1cc2nccc(Oc3ccc(NC(=O)NCCN4CCCCC4)c(C)c3C)c2cc1OC.COc1cc2nccc(Oc3ccc(NC(=O)NCCN4CCCCC4)cc3)c2cc1OC.COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCCC4)c(Cl)c3)c2cc1OC.COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCCC4)cc3)c2cc1OC
InChIInChI=1S/C30H34N4O5.C29H31ClN4O4.C29H33N5O5.C28H38N4O4.C27H36N4O5.2C27H34N4O4.C25H30N4O4.C24H28ClN5O4.C24H29N5O4/c1-6-34(21-9-7-8-20(2)16-21)15-14-32-30(35)33-24-11-10-22(17-27(24)36-3)39-26-12-13-31-25-19-29(38-5)28(37-4)18-23(25)26;1-5-34(20-8-6-7-19(2)15-20)14-13-32-29(35)33-24-10-9-21(16-23(24)30)38-26-11-12-31-25-18-28(37-4)27(36-3)17-22(25)26;1-6-34(20-9-7-8-19(2)14-20)13-12-30-29(35)33-23-11-10-21(15-25(23)36-3)39-28-22-16-26(37-4)27(38-5)17-24(22)31-18-32-28;1-17(2)32(18(3)4)12-11-30-28(33)31-22-13-20(6)25(14-19(22)5)36-24-9-10-29-23-16-27(35-8)26(34-7)15-21(23)24;1-17(2)31(18(3)4)13-12-29-27(32)30-21-9-8-19(14-24(21)33-5)36-23-10-11-28-22-16-26(35-7)25(34-6)15-20(22)23;1-18-19(2)23(9-8-21(18)30-27(32)29-12-15-31-13-6-5-7-14-31)35-24-10-11-28-22-17-26(34-4)25(33-3)16-20(22)24;1-18-15-24(35-23-8-9-28-22-17-26(34-4)25(33-3)16-20(22)23)19(2)14-21(18)30-27(32)29-10-13-31-11-6-5-7-12-31;1-31-23-16-20-21(17-24(23)32-2)26-11-10-22(20)33-19-8-6-18(7-9-19)28-25(30)27-12-15-29-13-4-3-5-14-29;1-32-21-13-17-20(14-22(21)33-2)27-15-28-23(17)34-16-6-7-19(18(25)12-16)29-24(31)26-8-11-30-9-4-3-5-10-30;1-31-21-14-19-20(15-22(21)32-2)26-16-27-23(19)33-18-8-6-17(7-9-18)28-24(30)25-10-13-29-11-4-3-5-12-29/h7-13,16-19H,6,14-15H2,1-5H3,(H2,32,33,35);6-12,15-18H,5,13-14H2,1-4H3,(H2,32,33,35);7-11,14-18H,6,12-13H2,1-5H3,(H2,30,33,35);9-10,13-18H,11-12H2,1-8H3,(H2,30,31,33);8-11,14-18H,12-13H2,1-7H3,(H2,29,30,32);8-11,16-17H,5-7,12-15H2,1-4H3,(H2,29,30,32);8-9,14-17H,5-7,10-13H2,1-4H3,(H2,29,30,32);6-11,16-17H,3-5,12-15H2,1-2H3,(H2,27,28,30);6-7,12-15H,3-5,8-11H2,1-2H3,(H2,26,29,31);6-9,14-16H,3-5,10-13H2,1-2H3,(H2,25,28,30)
InChIKeyNFZZAXXGRQRZBE-UHFFFAOYSA-N
MW4933.75 g/mol
LogP53.20
Rot. Bonds93

About 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea

1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea (PubChem CID 159770164) has the molecular formula C270H327Cl2N43O43 and a molecular weight of 4933.75 g/mol. Its IUPAC name is 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea.

Molecular Properties

Compound Name1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea
PubChem CID159770164
Molecular FormulaC270H327Cl2N43O43
Molecular Weight4933.75 g/mol
Exact Mass4929.41
IUPAC Name1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea
SMILESCCN(CCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1Cl)c1cccc(C)c1.CCN(CCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1OC)c1cccc(C)c1.CCN(CCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC)c1cccc(C)c1.COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NCCN(C(C)C)C(C)C.COc1cc2nccc(Oc3cc(C)c(NC(=O)NCCN(C(C)C)C(C)C)cc3C)c2cc1OC.COc1cc2nccc(Oc3cc(C)c(NC(=O)NCCN4CCCCC4)cc3C)c2cc1OC.COc1cc2nccc(Oc3ccc(NC(=O)NCCN4CCCCC4)c(C)c3C)c2cc1OC.COc1cc2nccc(Oc3ccc(NC(=O)NCCN4CCCCC4)cc3)c2cc1OC.COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCCC4)c(Cl)c3)c2cc1OC.COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCCC4)cc3)c2cc1OC
InChIInChI=1S/C30H34N4O5.C29H31ClN4O4.C29H33N5O5.C28H38N4O4.C27H36N4O5.2C27H34N4O4.C25H30N4O4.C24H28ClN5O4.C24H29N5O4/c1-6-34(21-9-7-8-20(2)16-21)15-14-32-30(35)33-24-11-10-22(17-27(24)36-3)39-26-12-13-31-25-19-29(38-5)28(37-4)18-23(25)26;1-5-34(20-8-6-7-19(2)15-20)14-13-32-29(35)33-24-10-9-21(16-23(24)30)38-26-11-12-31-25-18-28(37-4)27(36-3)17-22(25)26;1-6-34(20-9-7-8-19(2)14-20)13-12-30-29(35)33-23-11-10-21(15-25(23)36-3)39-28-22-16-26(37-4)27(38-5)17-24(22)31-18-32-28;1-17(2)32(18(3)4)12-11-30-28(33)31-22-13-20(6)25(14-19(22)5)36-24-9-10-29-23-16-27(35-8)26(34-7)15-21(23)24;1-17(2)31(18(3)4)13-12-29-27(32)30-21-9-8-19(14-24(21)33-5)36-23-10-11-28-22-16-26(35-7)25(34-6)15-20(22)23;1-18-19(2)23(9-8-21(18)30-27(32)29-12-15-31-13-6-5-7-14-31)35-24-10-11-28-22-17-26(34-4)25(33-3)16-20(22)24;1-18-15-24(35-23-8-9-28-22-17-26(34-4)25(33-3)16-20(22)23)19(2)14-21(18)30-27(32)29-10-13-31-11-6-5-7-12-31;1-31-23-16-20-21(17-24(23)32-2)26-11-10-22(20)33-19-8-6-18(7-9-19)28-25(30)27-12-15-29-13-4-3-5-14-29;1-32-21-13-17-20(14-22(21)33-2)27-15-28-23(17)34-16-6-7-19(18(25)12-16)29-24(31)26-8-11-30-9-4-3-5-10-30;1-31-21-14-19-20(15-22(21)32-2)26-16-27-23(19)33-18-8-6-17(7-9-18)28-24(30)25-10-13-29-11-4-3-5-12-29/h7-13,16-19H,6,14-15H2,1-5H3,(H2,32,33,35);6-12,15-18H,5,13-14H2,1-4H3,(H2,32,33,35);7-11,14-18H,6,12-13H2,1-5H3,(H2,30,33,35);9-10,13-18H,11-12H2,1-8H3,(H2,30,31,33);8-11,14-18H,12-13H2,1-7H3,(H2,29,30,32);8-11,16-17H,5-7,12-15H2,1-4H3,(H2,29,30,32);8-9,14-17H,5-7,10-13H2,1-4H3,(H2,29,30,32);6-11,16-17H,3-5,12-15H2,1-2H3,(H2,27,28,30);6-7,12-15H,3-5,8-11H2,1-2H3,(H2,26,29,31);6-9,14-16H,3-5,10-13H2,1-2H3,(H2,25,28,30)
InChIKeyNFZZAXXGRQRZBE-UHFFFAOYSA-N
XLogP53.20
TPSA915.86 Ų
H-Bond Donors20
H-Bond Acceptors66
Rotatable Bonds93
Heavy Atoms358
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004933.75
LogP ≤ 553.20
H-Bond Donors ≤ 520
H-Bond Acceptors ≤ 1066

Analyze 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea with MolForge

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Related Compounds

1-[2-Chloro-4-[[5-(3-morpholin-4-ylpropoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl]oxy]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
CID 146403716
1-[2-Chloro-4-[6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-yl]oxyphenyl]-3-(2,4-dimethoxyphenyl)urea
CID 164900955
US10980809, Example 56
CID 146403805
US10980809, Example 33
CID 146403815
US10980809, Example 87
CID 146421572
US10980809, Example 64
CID 146422883
1-[2-Chloro-4-[[5-(3-morpholin-4-ylpropoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl]oxy]phenyl]-3-[1-(4-fluorophenyl)ethyl]urea
CID 146438511
1-[2-chloro-4-[[5-[3-(4-methylpiperazin-1-yl)propoxy]-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl]oxy]phenyl]-3-[(1R)-1-(4-fluorophenyl)ethyl]urea
CID 146438650
1-[2-chloro-4-[[5-(3-piperidin-1-ylpropoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl]oxy]phenyl]-3-[(1R)-1-(4-fluorophenyl)ethyl]urea
CID 146438655
1-[2-chloro-4-[[5-(3-pyrrolidin-1-ylpropoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl]oxy]phenyl]-3-[(1R)-1-(4-fluorophenyl)ethyl]urea
CID 146438660
1-[2-Chloro-4-[[5-(3-morpholin-4-ylpropoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl]oxy]phenyl]-3-[(4-fluorophenyl)methyl]urea
CID 146438736
1-[2-chloro-4-[[5-(3-morpholin-4-ylpropoxy)-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-yl]oxy]phenyl]-3-[(1R)-1-(4-fluorophenyl)ethyl]urea
CID 146438760

Frequently Asked Questions

What is the IUPAC name of 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea?
The IUPAC name of 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea (CID 159770164) is 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea.
What is the SMILES notation for 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea?
The canonical SMILES for 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea is CCN(CCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1Cl)c1cccc(C)c1.CCN(CCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1OC)c1cccc(C)c1.CCN(CCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC)c1cccc(C)c1.COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NCCN(C(C)C)C(C)C.COc1cc2nccc(Oc3cc(C)c(NC(=O)NCCN(C(C)C)C(C)C)cc3C)c2cc1OC.COc1cc2nccc(Oc3cc(C)c(NC(=O)NCCN4CCCCC4)cc3C)c2cc1OC.COc1cc2nccc(Oc3ccc(NC(=O)NCCN4CCCCC4)c(C)c3C)c2cc1OC.COc1cc2nccc(Oc3ccc(NC(=O)NCCN4CCCCC4)cc3)c2cc1OC.COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCCC4)c(Cl)c3)c2cc1OC.COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCCC4)cc3)c2cc1OC.
What is the InChIKey of 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea?
The InChIKey is NFZZAXXGRQRZBE-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H34N4O5.C29H31ClN4O4.C29H33N5O5.C28H38N4O4.C27H36N4O5.2C27H34N4O4.C25H30N4O4.C24H28ClN5O4.C24H29N5O4/c1-6-34(21-9-7-8-20(2)16-21)15-14-32-30(35)33-24-11-10-22(17-27(24)36-3)39-26-12-13-31-25-19-29(38-5)28(37-4)18-23(25)26;1-5-34(20-8-6-7-19(2)15-20)14-13-32-29(35)33-24-10-9-21(16-23(24)30)38-26-11-12-31-25-18-28(37-4)27(36-3)17-22(25)26;1-6-34(20-9-7-8-19(2)14-20)13-12-30-29(35)33-23-11-10-21(15-25(23)36-3)39-28-22-16-26(37-4)27(38-5)17-24(22)31-18-32-28;1-17(2)32(18(3)4)12-11-30-28(33)31-22-13-20(6)25(14-19(22)5)36-24-9-10-29-23-16-27(35-8)26(34-7)15-21(23)24;1-17(2)31(18(3)4)13-12-29-27(32)30-21-9-8-19(14-24(21)33-5)36-23-10-11-28-22-16-26(35-7)25(34-6)15-20(22)23;1-18-19(2)23(9-8-21(18)30-27(32)29-12-15-31-13-6-5-7-14-31)35-24-10-11-28-22-17-26(34-4)25(33-3)16-20(22)24;1-18-15-24(35-23-8-9-28-22-17-26(34-4)25(33-3)16-20(22)23)19(2)14-21(18)30-27(32)29-10-13-31-11-6-5-7-12-31;1-31-23-16-20-21(17-24(23)32-2)26-11-10-22(20)33-19-8-6-18(7-9-19)28-25(30)27-12-15-29-13-4-3-5-14-29;1-32-21-13-17-20(14-22(21)33-2)27-15-28-23(17)34-16-6-7-19(18(25)12-16)29-24(31)26-8-11-30-9-4-3-5-10-30;1-31-21-14-19-20(15-22(21)32-2)26-16-27-23(19)33-18-8-6-17(7-9-18)28-24(30)25-10-13-29-11-4-3-5-12-29/h7-13,16-19H,6,14-15H2,1-5H3,(H2,32,33,35);6-12,15-18H,5,13-14H2,1-4H3,(H2,32,33,35);7-11,14-18H,6,12-13H2,1-5H3,(H2,30,33,35);9-10,13-18H,11-12H2,1-8H3,(H2,30,31,33);8-11,14-18H,12-13H2,1-7H3,(H2,29,30,32);8-11,16-17H,5-7,12-15H2,1-4H3,(H2,29,30,32);8-9,14-17H,5-7,10-13H2,1-4H3,(H2,29,30,32);6-11,16-17H,3-5,12-15H2,1-2H3,(H2,27,28,30);6-7,12-15H,3-5,8-11H2,1-2H3,(H2,26,29,31);6-9,14-16H,3-5,10-13H2,1-2H3,(H2,25,28,30).
What are the key properties of 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea?
1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea has a molecular weight of 4933.75 g/mol, XLogP of 53.20, 93 rotatable bonds, 20 hydrogen bond donors, and 66 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,3-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2,5-dimethylphenyl]-3-(2-piperidin-1-ylethyl)urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-[di(propan-2-yl)amino]ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[2-(N-ethyl-3-methylanilino)ethyl]urea;1-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(2-piperidin-1-ylethyl)urea is sourced from PubChem (CID 159770164), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).