N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide

C134H130Cl6F18N36O12 — CID 159808954

IUPACN-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide
SMILESO=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCCC3(CCN3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(C3CC3)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CCF)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCNC3(CC3)C2)c(-c2ccn[nH]2)c1
InChIInChI=1S/2C23H23ClF2N6O2.C22H20ClF5N6O2.C22H21ClF4N6O2.C22H22ClF3N6O2.C22H21ClF2N6O2/c24-23(25,26)34-18-5-1-16(2-6-18)29-22(33)15-13-19(20-7-8-28-30-20)21(27-14-15)32-11-9-31(10-12-32)17-3-4-17;24-23(25,26)34-17-4-2-16(3-5-17)30-21(33)15-12-18(19-6-9-29-31-19)20(27-13-15)32-11-1-7-22(14-32)8-10-28-22;23-22(27,28)36-16-3-1-15(2-4-16)31-20(35)14-11-17(18-5-6-30-32-18)19(29-12-14)34-9-7-33(8-10-34)13-21(24,25)26;23-22(26,27)35-16-3-1-15(2-4-16)30-21(34)14-11-17(18-5-6-29-31-18)20(28-12-14)33-9-7-32(8-10-33)13-19(24)25;23-22(25,26)34-17-3-1-16(2-4-17)29-21(33)15-13-18(19-5-7-28-30-19)20(27-14-15)32-11-9-31(8-6-24)10-12-32;23-22(24,25)33-16-3-1-15(2-4-16)29-20(32)14-11-17(18-5-8-28-30-18)19(26-12-14)31-10-9-27-21(13-31)6-7-21/h1-2,5-8,13-14,17H,3-4,9-12H2,(H,28,30)(H,29,33);2-6,9,12-13,28H,1,7-8,10-11,14H2,(H,29,31)(H,30,33);1-6,11-12H,7-10,13H2,(H,30,32)(H,31,35);1-6,11-12,19H,7-10,13H2,(H,29,31)(H,30,34);1-5,7,13-14H,6,8-12H2,(H,28,30)(H,29,33);1-5,8,11-12,27H,6-7,9-10,13H2,(H,28,30)(H,29,32)
InChIKeyNKTQPKZLGIHQMR-UHFFFAOYSA-N
MW2991.44 g/mol
LogP25.07
Rot. Bonds42

About N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide

N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide (PubChem CID 159808954) has the molecular formula C134H130Cl6F18N36O12 and a molecular weight of 2991.44 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide
PubChem CID159808954
Molecular FormulaC134H130Cl6F18N36O12
Molecular Weight2991.44 g/mol
Exact Mass2986.85
IUPAC NameN-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide
SMILESO=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCCC3(CCN3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(C3CC3)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CCF)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCNC3(CC3)C2)c(-c2ccn[nH]2)c1
InChIInChI=1S/2C23H23ClF2N6O2.C22H20ClF5N6O2.C22H21ClF4N6O2.C22H22ClF3N6O2.C22H21ClF2N6O2/c24-23(25,26)34-18-5-1-16(2-6-18)29-22(33)15-13-19(20-7-8-28-30-20)21(27-14-15)32-11-9-31(10-12-32)17-3-4-17;24-23(25,26)34-17-4-2-16(3-5-17)30-21(33)15-12-18(19-6-9-29-31-19)20(27-13-15)32-11-1-7-22(14-32)8-10-28-22;23-22(27,28)36-16-3-1-15(2-4-16)31-20(35)14-11-17(18-5-6-30-32-18)19(29-12-14)34-9-7-33(8-10-34)13-21(24,25)26;23-22(26,27)35-16-3-1-15(2-4-16)30-21(34)14-11-17(18-5-6-29-31-18)20(28-12-14)33-9-7-32(8-10-33)13-19(24)25;23-22(25,26)34-17-3-1-16(2-4-17)29-21(33)15-13-18(19-5-7-28-30-19)20(27-14-15)32-11-9-31(8-6-24)10-12-32;23-22(24,25)33-16-3-1-15(2-4-16)29-20(32)14-11-17(18-5-8-28-30-18)19(26-12-14)31-10-9-27-21(13-31)6-7-21/h1-2,5-8,13-14,17H,3-4,9-12H2,(H,28,30)(H,29,33);2-6,9,12-13,28H,1,7-8,10-11,14H2,(H,29,31)(H,30,33);1-6,11-12H,7-10,13H2,(H,30,32)(H,31,35);1-6,11-12,19H,7-10,13H2,(H,29,31)(H,30,34);1-5,7,13-14H,6,8-12H2,(H,28,30)(H,29,33);1-5,8,11-12,27H,6-7,9-10,13H2,(H,28,30)(H,29,32)
InChIKeyNKTQPKZLGIHQMR-UHFFFAOYSA-N
XLogP25.07
TPSA535.86 Ų
H-Bond Donors14
H-Bond Acceptors36
Rotatable Bonds42
Heavy Atoms206
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002991.44
LogP ≤ 525.07
H-Bond Donors ≤ 514
H-Bond Acceptors ≤ 1036

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'alkyl_halide', 'substructure': 'N/A'}

Analyze N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide?
The IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide (CID 159808954) is N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide.
What is the SMILES notation for N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide?
The canonical SMILES for N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide is O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCCC3(CCN3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(C3CC3)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CCF)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCNC3(CC3)C2)c(-c2ccn[nH]2)c1.
What is the InChIKey of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide?
The InChIKey is NKTQPKZLGIHQMR-UHFFFAOYSA-N. The full InChI is InChI=1S/2C23H23ClF2N6O2.C22H20ClF5N6O2.C22H21ClF4N6O2.C22H22ClF3N6O2.C22H21ClF2N6O2/c24-23(25,26)34-18-5-1-16(2-6-18)29-22(33)15-13-19(20-7-8-28-30-20)21(27-14-15)32-11-9-31(10-12-32)17-3-4-17;24-23(25,26)34-17-4-2-16(3-5-17)30-21(33)15-12-18(19-6-9-29-31-19)20(27-13-15)32-11-1-7-22(14-32)8-10-28-22;23-22(27,28)36-16-3-1-15(2-4-16)31-20(35)14-11-17(18-5-6-30-32-18)19(29-12-14)34-9-7-33(8-10-34)13-21(24,25)26;23-22(26,27)35-16-3-1-15(2-4-16)30-21(34)14-11-17(18-5-6-29-31-18)20(28-12-14)33-9-7-32(8-10-33)13-19(24)25;23-22(25,26)34-17-3-1-16(2-4-17)29-21(33)15-13-18(19-5-7-28-30-19)20(27-14-15)32-11-9-31(8-6-24)10-12-32;23-22(24,25)33-16-3-1-15(2-4-16)29-20(32)14-11-17(18-5-8-28-30-18)19(26-12-14)31-10-9-27-21(13-31)6-7-21/h1-2,5-8,13-14,17H,3-4,9-12H2,(H,28,30)(H,29,33);2-6,9,12-13,28H,1,7-8,10-11,14H2,(H,29,31)(H,30,33);1-6,11-12H,7-10,13H2,(H,30,32)(H,31,35);1-6,11-12,19H,7-10,13H2,(H,29,31)(H,30,34);1-5,7,13-14H,6,8-12H2,(H,28,30)(H,29,33);1-5,8,11-12,27H,6-7,9-10,13H2,(H,28,30)(H,29,32).
What are the key properties of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide?
N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide has a molecular weight of 2991.44 g/mol, XLogP of 25.07, 42 rotatable bonds, 14 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide is sourced from PubChem (CID 159808954), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).