6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one

C152H159N29O13S — CID 159852184

About 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one

6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one (PubChem CID 159852184) has the molecular formula C152H159N29O13S and a molecular weight of 2632.20 g/mol. Its IUPAC name is 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one.

Molecular Properties

• Compound Name: 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one
• PubChem CID: 159852184
• Molecular Formula: C152H159N29O13S
• Molecular Weight: 2632.20 g/mol
• Exact Mass: 2630.24
• IUPAC Name: 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one
• SMILES: C=C(c1cc2cnc(Nc3ccc(OC4CCN(C)C4)cc3)nc2n(C2COc3ccccc3C2=O)c1=O)C(C)C.C=C(c1cc2cnc(Nc3ccc(OC4CCNCC4)cc3)nc2n(C2Cc3ccccc3N(C)C2)c1=O)C1CC1.C=C1C=Cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2N1C1CSc2ccccc2C1.CCOc1cc2cnc(Nc3ccc(OC4CCCNC4)cc3)nc2n(C2CNc3ccccc3C2=O)c1=O.CN1CCOC(c2ccc(Nc3ncc4cc(C5CC5)c(=O)n(C5Cc6ccccc6C(=O)N5)c4n3)cc2)C1
• InChI: InChI=1S/C33H36N6O2.C32H33N5O4.C30H30N6O3.C29H30N6O4.C28H30N6S/c1-21(22-7-8-22)29-18-24-19-35-33(36-25-9-11-27(12-10-25)41-28-13-15-34-16-14-28)37-31(24)39(32(29)40)26-17-23-5-3-4-6-30(23)38(2)20-26;1-19(2)20(3)26-15-21-16-33-32(34-22-9-11-23(12-10-22)41-24-13-14-36(4)17-24)35-30(21)37(31(26)39)27-18-40-28-8-6-5-7-25(28)29(27)38;1-35-12-13-39-25(17-35)19-8-10-22(11-9-19)32-30-31-16-21-14-24(18-6-7-18)29(38)36(27(21)34-30)26-15-20-4-2-3-5-23(20)28(37)33-26;1-2-38-25-14-18-15-32-29(33-19-9-11-20(12-10-19)39-21-6-5-13-30-16-21)34-27(18)35(28(25)37)24-17-31-23-8-4-3-7-22(23)26(24)36;1-20-7-8-22-18-29-28(30-23-9-11-24(12-10-23)33-15-13-32(2)14-16-33)31-27(22)34(20)25-17-21-5-3-4-6-26(21)35-19-25/h3-6,9-12,18-19,22,26,28,34H,1,7-8,13-17,20H2,2H3,(H,35,36,37);5-12,15-16,19,24,27H,3,13-14,17-18H2,1-2,4H3,(H,33,34,35);2-5,8-11,14,16,18,25-26H,6-7,12-13,15,17H2,1H3,(H,33,37)(H,31,32,34);3-4,7-12,14-15,21,24,30-31H,2,5-6,13,16-17H2,1H3,(H,32,33,34);3-12,18,25H,1,13-17,19H2,2H3,(H,29,30,31)
• InChIKey: NQBQPUADXWALFJ-UHFFFAOYSA-N
• XLogP: 23.28
• TPSA: 451.20 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 42
• Rotatable Bonds: 30
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2632.20
LogP ≤ 5	23.28
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one?

The IUPAC name of 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one (CID 159852184) is 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one.

What is the SMILES notation for 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one?

The canonical SMILES for 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one is C=C(c1cc2cnc(Nc3ccc(OC4CCN(C)C4)cc3)nc2n(C2COc3ccccc3C2=O)c1=O)C(C)C.C=C(c1cc2cnc(Nc3ccc(OC4CCNCC4)cc3)nc2n(C2Cc3ccccc3N(C)C2)c1=O)C1CC1.C=C1C=Cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2N1C1CSc2ccccc2C1.CCOc1cc2cnc(Nc3ccc(OC4CCCNC4)cc3)nc2n(C2CNc3ccccc3C2=O)c1=O.CN1CCOC(c2ccc(Nc3ncc4cc(C5CC5)c(=O)n(C5Cc6ccccc6C(=O)N5)c4n3)cc2)C1.

What is the InChIKey of 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one?

The InChIKey is NQBQPUADXWALFJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H36N6O2.C32H33N5O4.C30H30N6O3.C29H30N6O4.C28H30N6S/c1-21(22-7-8-22)29-18-24-19-35-33(36-25-9-11-27(12-10-25)41-28-13-15-34-16-14-28)37-31(24)39(32(29)40)26-17-23-5-3-4-6-30(23)38(2)20-26;1-19(2)20(3)26-15-21-16-33-32(34-22-9-11-23(12-10-22)41-24-13-14-36(4)17-24)35-30(21)37(31(26)39)27-18-40-28-8-6-5-7-25(28)29(27)38;1-35-12-13-39-25(17-35)19-8-10-22(11-9-19)32-30-31-16-21-14-24(18-6-7-18)29(38)36(27(21)34-30)26-15-20-4-2-3-5-23(20)28(37)33-26;1-2-38-25-14-18-15-32-29(33-19-9-11-20(12-10-19)39-21-6-5-13-30-16-21)34-27(18)35(28(25)37)24-17-31-23-8-4-3-7-22(23)26(24)36;1-20-7-8-22-18-29-28(30-23-9-11-24(12-10-23)33-15-13-32(2)14-16-33)31-27(22)34(20)25-17-21-5-3-4-6-26(21)35-19-25/h3-6,9-12,18-19,22,26,28,34H,1,7-8,13-17,20H2,2H3,(H,35,36,37);5-12,15-16,19,24,27H,3,13-14,17-18H2,1-2,4H3,(H,33,34,35);2-5,8-11,14,16,18,25-26H,6-7,12-13,15,17H2,1H3,(H,33,37)(H,31,32,34);3-4,7-12,14-15,21,24,30-31H,2,5-6,13,16-17H2,1H3,(H,32,33,34);3-12,18,25H,1,13-17,19H2,2H3,(H,29,30,31).

What are the key properties of 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one?

6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one has a molecular weight of 2632.20 g/mol, XLogP of 23.28, 30 rotatable bonds, 9 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(1-cyclopropylethenyl)-8-(1-methyl-3,4-dihydro-2H-quinolin-3-yl)-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-cyclopropyl-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1-oxo-3,4-dihydro-2H-isoquinolin-3-yl)pyrido[2,3-d]pyrimidin-7-one;8-(3,4-dihydro-2H-thiochromen-3-yl)-7-methylidene-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine;6-ethoxy-8-(4-oxo-2,3-dihydro-1H-quinolin-3-yl)-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-(3-methylbut-1-en-2-yl)-2-[4-(1-methylpyrrolidin-3-yl)oxyanilino]-8-(4-oxo-2,3-dihydrochromen-3-yl)pyrido[2,3-d]pyrimidin-7-one is sourced from PubChem (CID 159852184), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).