5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine

C127H100F26N22O7 — CID 159895775

About 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine

5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine (PubChem CID 159895775) has the molecular formula C127H100F26N22O7 and a molecular weight of 2540.29 g/mol. Its IUPAC name is 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine.

Molecular Properties

• Compound Name: 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine
• PubChem CID: 159895775
• Molecular Formula: C127H100F26N22O7
• Molecular Weight: 2540.29 g/mol
• Exact Mass: 2538.77
• IUPAC Name: 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine
• SMILES: CC(C)(Oc1ncc(-c2ccn3nccc3c2)cc1F)C(F)(F)F.COCc1nnn2ccc(-c3cnc(OCC(F)(F)F)c(F)c3)cc12.C[C@H](Oc1ncc(-c2ccn3nccc3c2)cc1F)C(F)(F)F.Cc1cnn2ccc(-c3cnc(O[C@@H](C)C(F)(F)F)c(F)c3)cc12.Cc1cnn2ccc(-c3cnc(O[C@H](C)C(F)(F)F)c(F)c3)cc12.FC1(F)CC(Oc2ccc(-c3ccn4nccc4c3)cc2)C1.FC1(F)C[C@@H]1c1ccc(-c2ccn3nccc3c2)cc1.FC1(F)C[C@H]1c1ccc(-c2ccn3nccc3c2)cc1
• InChI: InChI=1S/C17H14F2N2O.3C16H13F4N3O.2C16H12F2N2.C15H12F4N4O2.C15H11F4N3O/c18-17(19)10-16(11-17)22-15-3-1-12(2-4-15)13-6-8-21-14(9-13)5-7-20-21;1-15(2,16(18,19)20)24-14-13(17)8-11(9-21-14)10-4-6-23-12(7-10)3-5-22-23;2*1-9-7-22-23-4-3-11(6-14(9)23)12-5-13(17)15(21-8-12)24-10(2)16(18,19)20;2*17-16(18)10-15(16)12-3-1-11(2-4-12)13-6-8-20-14(9-13)5-7-19-20;1-24-7-12-13-5-9(2-3-23(13)22-21-12)10-4-11(16)14(20-6-10)25-8-15(17,18)19;1-9(15(17,18)19)23-14-13(16)7-11(8-20-14)10-3-5-22-12(6-10)2-4-21-22/h1-9,16H,10-11H2;3-9H,1-2H3;2*3-8,10H,1-2H3;2*1-9,15H,10H2;2-6H,7-8H2,1H3;2-9H,1H3/t;;2*10-;2*15-;;9-/m..1010.0/s1
• InChIKey: NVIBDIOXZLUBFA-KEWOWEFTSA-N
• XLogP: 31.91
• TPSA: 280.35 Ų
• H-Bond Acceptors: 29
• Rotatable Bonds: 24
• Heavy Atoms: 182
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2540.29
LogP ≤ 5	31.91
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine?

The IUPAC name of 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine (CID 159895775) is 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine.

What is the SMILES notation for 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine?

The canonical SMILES for 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine is CC(C)(Oc1ncc(-c2ccn3nccc3c2)cc1F)C(F)(F)F.COCc1nnn2ccc(-c3cnc(OCC(F)(F)F)c(F)c3)cc12.C[C@H](Oc1ncc(-c2ccn3nccc3c2)cc1F)C(F)(F)F.Cc1cnn2ccc(-c3cnc(O[C@@H](C)C(F)(F)F)c(F)c3)cc12.Cc1cnn2ccc(-c3cnc(O[C@H](C)C(F)(F)F)c(F)c3)cc12.FC1(F)CC(Oc2ccc(-c3ccn4nccc4c3)cc2)C1.FC1(F)C[C@@H]1c1ccc(-c2ccn3nccc3c2)cc1.FC1(F)C[C@H]1c1ccc(-c2ccn3nccc3c2)cc1.

What is the InChIKey of 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine?

The InChIKey is NVIBDIOXZLUBFA-KEWOWEFTSA-N. The full InChI is InChI=1S/C17H14F2N2O.3C16H13F4N3O.2C16H12F2N2.C15H12F4N4O2.C15H11F4N3O/c18-17(19)10-16(11-17)22-15-3-1-12(2-4-15)13-6-8-21-14(9-13)5-7-20-21;1-15(2,16(18,19)20)24-14-13(17)8-11(9-21-14)10-4-6-23-12(7-10)3-5-22-23;2*1-9-7-22-23-4-3-11(6-14(9)23)12-5-13(17)15(21-8-12)24-10(2)16(18,19)20;2*17-16(18)10-15(16)12-3-1-11(2-4-12)13-6-8-20-14(9-13)5-7-19-20;1-24-7-12-13-5-9(2-3-23(13)22-21-12)10-4-11(16)14(20-6-10)25-8-15(17,18)19;1-9(15(17,18)19)23-14-13(16)7-11(8-20-14)10-3-5-22-12(6-10)2-4-21-22/h1-9,16H,10-11H2;3-9H,1-2H3;2*3-8,10H,1-2H3;2*1-9,15H,10H2;2-6H,7-8H2,1H3;2-9H,1H3/t;;2*10-;2*15-;;9-/m..1010.0/s1.

What are the key properties of 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine?

5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine has a molecular weight of 2540.29 g/mol, XLogP of 31.91, 24 rotatable bonds, 0 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[4-(3,3-difluorocyclobutyl)oxyphenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1R)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[4-[(1S)-2,2-difluorocyclopropyl]phenyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(methoxymethyl)triazolo[1,5-a]pyridine;5-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2R)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]-3-methylpyrazolo[1,5-a]pyridine;5-[5-fluoro-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyridine is sourced from PubChem (CID 159895775), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).