1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide

C109H108F5N25O21S5 — CID 159903398

About 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide

1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide (PubChem CID 159903398) has the molecular formula C109H108F5N25O21S5 and a molecular weight of 2359.54 g/mol. Its IUPAC name is 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide.

Molecular Properties

• Compound Name: 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide
• PubChem CID: 159903398
• Molecular Formula: C109H108F5N25O21S5
• Molecular Weight: 2359.54 g/mol
• Exact Mass: 2357.67
• IUPAC Name: 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide
• SMILES: CC[C@H](NC(=O)c1cncc2c1cnn2C1CCC(F)(F)CC1)c1ccnc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2C1CCOCC1)c1cncc(S(C)(=O)=O)c1.COC(=O)C[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1.CS(=O)(=O)c1cc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cc(=O)[nH]1.CS(=O)(=O)c1cc([C@H](C[C@@H](O)CO)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1
• InChI: InChI=1S/C23H20FN5O5S.C23H22FN5O5S.C22H25F2N5O3S.C21H25N5O4S.C20H16FN5O4S/c1-34-22(30)10-19(14-7-8-26-21(9-14)35(2,32)33)28-23(31)18-11-25-13-20-17(18)12-27-29(20)16-5-3-15(24)4-6-16;1-35(33,34)22-8-14(6-7-26-22)20(9-17(31)13-30)28-23(32)19-10-25-12-21-18(19)11-27-29(21)16-4-2-15(24)3-5-16;1-3-18(14-6-9-26-20(10-14)33(2,31)32)28-21(30)17-11-25-13-19-16(17)12-27-29(19)15-4-7-22(23,24)8-5-15;1-3-19(14-8-16(10-22-9-14)31(2,28)29)25-21(27)18-11-23-13-20-17(18)12-24-26(20)15-4-6-30-7-5-15;1-31(29,30)19-7-12(6-18(27)25-19)8-23-20(28)16-9-22-11-17-15(16)10-24-26(17)14-4-2-13(21)3-5-14/h3-9,11-13,19H,10H2,1-2H3,(H,28,31);2-8,10-12,17,20,30-31H,9,13H2,1H3,(H,28,32);6,9-13,15,18H,3-5,7-8H2,1-2H3,(H,28,30);8-13,15,19H,3-7H2,1-2H3,(H,25,27);2-7,9-11H,8H2,1H3,(H,23,28)(H,25,27)/t19-;17-,20+;18-;19-;/m0100./s1
• InChIKey: NWGDFHMPCIZNJB-XCMIVQMWSA-N
• XLogP: 11.87
• TPSA: 630.16 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 40
• Rotatable Bonds: 32
• Heavy Atoms: 165
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2359.54
LogP ≤ 5	11.87
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	40

Frequently Asked Questions

What is the IUPAC name of 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The IUPAC name of 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide (CID 159903398) is 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide.

What is the SMILES notation for 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The canonical SMILES for 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide is CC[C@H](NC(=O)c1cncc2c1cnn2C1CCC(F)(F)CC1)c1ccnc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1cncc2c1cnn2C1CCOCC1)c1cncc(S(C)(=O)=O)c1.COC(=O)C[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1.CS(=O)(=O)c1cc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cc(=O)[nH]1.CS(=O)(=O)c1cc([C@H](C[C@@H](O)CO)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1.

What is the InChIKey of 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The InChIKey is NWGDFHMPCIZNJB-XCMIVQMWSA-N. The full InChI is InChI=1S/C23H20FN5O5S.C23H22FN5O5S.C22H25F2N5O3S.C21H25N5O4S.C20H16FN5O4S/c1-34-22(30)10-19(14-7-8-26-21(9-14)35(2,32)33)28-23(31)18-11-25-13-20-17(18)12-27-29(20)16-5-3-15(24)4-6-16;1-35(33,34)22-8-14(6-7-26-22)20(9-17(31)13-30)28-23(32)19-10-25-12-21-18(19)11-27-29(21)16-4-2-15(24)3-5-16;1-3-18(14-6-9-26-20(10-14)33(2,31)32)28-21(30)17-11-25-13-19-16(17)12-27-29(19)15-4-7-22(23,24)8-5-15;1-3-19(14-8-16(10-22-9-14)31(2,28)29)25-21(27)18-11-23-13-20-17(18)12-24-26(20)15-4-6-30-7-5-15;1-31(29,30)19-7-12(6-18(27)25-19)8-23-20(28)16-9-22-11-17-15(16)10-24-26(17)14-4-2-13(21)3-5-14/h3-9,11-13,19H,10H2,1-2H3,(H,28,31);2-8,10-12,17,20,30-31H,9,13H2,1H3,(H,28,32);6,9-13,15,18H,3-5,7-8H2,1-2H3,(H,28,30);8-13,15,19H,3-7H2,1-2H3,(H,25,27);2-7,9-11H,8H2,1H3,(H,23,28)(H,25,27)/t19-;17-,20+;18-;19-;/m0100./s1.

What are the key properties of 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide?

1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide has a molecular weight of 2359.54 g/mol, XLogP of 11.87, 32 rotatable bonds, 8 hydrogen bond donors, and 40 hydrogen bond acceptors.

Where does this data come from?

All data for 1-(4,4-difluorocyclohexyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S,3R)-3,4-dihydroxy-1-(2-methylsulfonyl-4-pyridinyl)butyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide;methyl (3S)-3-[[1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carbonyl]amino]-3-(2-methylsulfonyl-4-pyridinyl)propanoate;N-[(1S)-1-(5-methylsulfonyl-3-pyridinyl)propyl]-1-(oxan-4-yl)pyrazolo[5,4-c]pyridine-4-carboxamide is sourced from PubChem (CID 159903398), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).