5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine

C110H107F18N25O7S6 — CID 159908694

About 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine

5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine (PubChem CID 159908694) has the molecular formula C110H107F18N25O7S6 and a molecular weight of 2425.60 g/mol. Its IUPAC name is 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine.

Molecular Properties

• Compound Name: 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine
• PubChem CID: 159908694
• Molecular Formula: C110H107F18N25O7S6
• Molecular Weight: 2425.60 g/mol
• Exact Mass: 2423.68
• IUPAC Name: 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine
• SMILES: CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)n(-c3ccccn3)n2)cc1.CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)n(-c3ccccn3)n2)s1.CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)nn2-c2ccccn2)s1.CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)nn2C2CCCC2)s1.Cc1cc(-c2ccc(C(=O)N(C)C)s2)n(-c2ccccn2)n1.Cc1cc(-c2ccc(C(=O)N(C)C)s2)n(CC(F)(F)F)n1.Cn1nc(-c2ccc(CNC[C@@H]3CCCO3)s2)cc1C(F)(F)F
• InChI: InChI=1S/C18H15F3N4O.2C16H13F3N4OS.C16H18F3N3OS.C16H16N4OS.C15H18F3N3OS.C13H14F3N3OS/c1-24(2)17(26)13-8-6-12(7-9-13)14-11-15(18(19,20)21)25(23-14)16-5-3-4-10-22-16;1-22(2)15(24)12-7-6-11(25-12)10-9-13(16(17,18)19)21-23(10)14-5-3-4-8-20-14;1-22(2)15(24)12-7-6-11(25-12)10-9-13(16(17,18)19)23(21-10)14-5-3-4-8-20-14;1-21(2)15(23)13-8-7-12(24-13)11-9-14(16(17,18)19)20-22(11)10-5-3-4-6-10;1-11-10-12(20(18-11)15-6-4-5-9-17-15)13-7-8-14(22-13)16(21)19(2)3;1-21-14(15(16,17)18)7-12(20-21)13-5-4-11(23-13)9-19-8-10-3-2-6-22-10;1-8-6-9(19(17-8)7-13(14,15)16)10-4-5-11(21-10)12(20)18(2)3/h3-11H,1-2H3;2*3-9H,1-2H3;7-10H,3-6H2,1-2H3;4-10H,1-3H3;4-5,7,10,19H,2-3,6,8-9H2,1H3;4-6H,7H2,1-3H3/t;;;;;10-;/m.....0./s1
• InChIKey: NWXBQAAJOTUMQG-BPKDBRQKSA-N
• XLogP: 25.16
• TPSA: 319.42 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 32
• Rotatable Bonds: 23
• Heavy Atoms: 166
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2425.60
LogP ≤ 5	25.16
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine?

The IUPAC name of 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine (CID 159908694) is 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine.

What is the SMILES notation for 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine?

The canonical SMILES for 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine is CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)n(-c3ccccn3)n2)cc1.CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)n(-c3ccccn3)n2)s1.CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)nn2-c2ccccn2)s1.CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)nn2C2CCCC2)s1.Cc1cc(-c2ccc(C(=O)N(C)C)s2)n(-c2ccccn2)n1.Cc1cc(-c2ccc(C(=O)N(C)C)s2)n(CC(F)(F)F)n1.Cn1nc(-c2ccc(CNC[C@@H]3CCCO3)s2)cc1C(F)(F)F.

What is the InChIKey of 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine?

The InChIKey is NWXBQAAJOTUMQG-BPKDBRQKSA-N. The full InChI is InChI=1S/C18H15F3N4O.2C16H13F3N4OS.C16H18F3N3OS.C16H16N4OS.C15H18F3N3OS.C13H14F3N3OS/c1-24(2)17(26)13-8-6-12(7-9-13)14-11-15(18(19,20)21)25(23-14)16-5-3-4-10-22-16;1-22(2)15(24)12-7-6-11(25-12)10-9-13(16(17,18)19)21-23(10)14-5-3-4-8-20-14;1-22(2)15(24)12-7-6-11(25-12)10-9-13(16(17,18)19)23(21-10)14-5-3-4-8-20-14;1-21(2)15(23)13-8-7-12(24-13)11-9-14(16(17,18)19)20-22(11)10-5-3-4-6-10;1-11-10-12(20(18-11)15-6-4-5-9-17-15)13-7-8-14(22-13)16(21)19(2)3;1-21-14(15(16,17)18)7-12(20-21)13-5-4-11(23-13)9-19-8-10-3-2-6-22-10;1-8-6-9(19(17-8)7-13(14,15)16)10-4-5-11(21-10)12(20)18(2)3/h3-11H,1-2H3;2*3-9H,1-2H3;7-10H,3-6H2,1-2H3;4-10H,1-3H3;4-5,7,10,19H,2-3,6,8-9H2,1H3;4-6H,7H2,1-3H3/t;;;;;10-;/m.....0./s1.

What are the key properties of 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine?

5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine has a molecular weight of 2425.60 g/mol, XLogP of 25.16, 23 rotatable bonds, 1 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[1-cyclopentyl-3-(trifluoromethyl)pyrazol-5-yl]-N,N-dimethylthiophene-2-carboxamide;N,N-dimethyl-5-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)thiophene-2-carboxamide;N,N-dimethyl-5-[5-methyl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]thiophene-2-carboxamide;N,N-dimethyl-4-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]benzamide;N,N-dimethyl-5-[1-pyridin-2-yl-3-(trifluoromethyl)pyrazol-5-yl]thiophene-2-carboxamide;N,N-dimethyl-5-[1-pyridin-2-yl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;N-[[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methyl]-1-[(2S)-oxolan-2-yl]methanamine is sourced from PubChem (CID 159908694), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).