1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone

C142H147Cl6F3N32O7 — CID 159917613

About 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone

1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone (PubChem CID 159917613) has the molecular formula C142H147Cl6F3N32O7 and a molecular weight of 2683.67 g/mol. Its IUPAC name is 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone.

Molecular Properties

• Compound Name: 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone
• PubChem CID: 159917613
• Molecular Formula: C142H147Cl6F3N32O7
• Molecular Weight: 2683.67 g/mol
• Exact Mass: 2679.02
• IUPAC Name: 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone
• SMILES: CC(C)c1ccc(-c2nc3ccccn3c2NCC(=O)N2CCN(c3ncccc3C#N)CC2)cc1.CCc1ccc(-c2nc3ccccn3c2NCC(=O)N2CCN(c3c(Cl)cccc3Cl)CC2)cc1.Cc1ccn2c(NCC(=O)N3CCN(c4c(Cl)cncc4Cl)CC3)c(-c3ccc(N4CCOCC4)cc3)nc2c1.O=C(CNc1c(-c2ccc(N3CCCC3)cc2)nc2ccccn12)N1CCN(c2ccccc2C(F)(F)F)CC1.O=C(CNc1c(-c2ccc(N3CCOCC3)cc2)nc2ccccn12)N1CCN(c2c(Cl)cncc2Cl)CC1
• InChI: InChI=1S/C30H31F3N6O.C29H31Cl2N7O2.C28H29Cl2N7O2.C28H29N7O.C27H27Cl2N5O/c31-30(32,33)24-7-1-2-8-25(24)37-17-19-38(20-18-37)27(40)21-34-29-28(35-26-9-3-4-16-39(26)29)22-10-12-23(13-11-22)36-14-5-6-15-36;1-20-6-7-38-25(16-20)34-27(21-2-4-22(5-3-21)35-12-14-40-15-13-35)29(38)33-19-26(39)36-8-10-37(11-9-36)28-23(30)17-32-18-24(28)31;29-22-17-31-18-23(30)27(22)36-11-9-35(10-12-36)25(38)19-32-28-26(33-24-3-1-2-8-37(24)28)20-4-6-21(7-5-20)34-13-15-39-16-14-34;1-20(2)21-8-10-22(11-9-21)26-28(35-13-4-3-7-24(35)32-26)31-19-25(36)33-14-16-34(17-15-33)27-23(18-29)6-5-12-30-27;1-2-19-9-11-20(12-10-19)25-27(34-13-4-3-8-23(34)31-25)30-18-24(35)32-14-16-33(17-15-32)26-21(28)6-5-7-22(26)29/h1-4,7-13,16,34H,5-6,14-15,17-21H2;2-7,16-18,33H,8-15,19H2,1H3;1-8,17-18,32H,9-16,19H2;3-13,20,31H,14-17,19H2,1-2H3;3-13,30H,2,14-18H2,1H3
• InChIKey: NXZHJXDNVDJSKE-UHFFFAOYSA-N
• XLogP: 24.07
• TPSA: 355.04 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 34
• Rotatable Bonds: 30
• Heavy Atoms: 190
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2683.67
LogP ≤ 5	24.07
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone?

The IUPAC name of 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone (CID 159917613) is 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone.

What is the SMILES notation for 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone?

The canonical SMILES for 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone is CC(C)c1ccc(-c2nc3ccccn3c2NCC(=O)N2CCN(c3ncccc3C#N)CC2)cc1.CCc1ccc(-c2nc3ccccn3c2NCC(=O)N2CCN(c3c(Cl)cccc3Cl)CC2)cc1.Cc1ccn2c(NCC(=O)N3CCN(c4c(Cl)cncc4Cl)CC3)c(-c3ccc(N4CCOCC4)cc3)nc2c1.O=C(CNc1c(-c2ccc(N3CCCC3)cc2)nc2ccccn12)N1CCN(c2ccccc2C(F)(F)F)CC1.O=C(CNc1c(-c2ccc(N3CCOCC3)cc2)nc2ccccn12)N1CCN(c2c(Cl)cncc2Cl)CC1.

What is the InChIKey of 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone?

The InChIKey is NXZHJXDNVDJSKE-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H31F3N6O.C29H31Cl2N7O2.C28H29Cl2N7O2.C28H29N7O.C27H27Cl2N5O/c31-30(32,33)24-7-1-2-8-25(24)37-17-19-38(20-18-37)27(40)21-34-29-28(35-26-9-3-4-16-39(26)29)22-10-12-23(13-11-22)36-14-5-6-15-36;1-20-6-7-38-25(16-20)34-27(21-2-4-22(5-3-21)35-12-14-40-15-13-35)29(38)33-19-26(39)36-8-10-37(11-9-36)28-23(30)17-32-18-24(28)31;29-22-17-31-18-23(30)27(22)36-11-9-35(10-12-36)25(38)19-32-28-26(33-24-3-1-2-8-37(24)28)20-4-6-21(7-5-20)34-13-15-39-16-14-34;1-20(2)21-8-10-22(11-9-21)26-28(35-13-4-3-7-24(35)32-26)31-19-25(36)33-14-16-34(17-15-33)27-23(18-29)6-5-12-30-27;1-2-19-9-11-20(12-10-19)25-27(34-13-4-3-8-23(34)31-25)30-18-24(35)32-14-16-33(17-15-32)26-21(28)6-5-7-22(26)29/h1-4,7-13,16,34H,5-6,14-15,17-21H2;2-7,16-18,33H,8-15,19H2,1H3;1-8,17-18,32H,9-16,19H2;3-13,20,31H,14-17,19H2,1-2H3;3-13,30H,2,14-18H2,1H3.

What are the key properties of 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone?

1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone has a molecular weight of 2683.67 g/mol, XLogP of 24.07, 30 rotatable bonds, 5 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[4-(2,6-dichlorophenyl)piperazin-1-yl]-2-[[2-(4-ethylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[7-methyl-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;1-[4-(3,5-dichloro-4-pyridinyl)piperazin-1-yl]-2-[[2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]ethanone;2-[4-[2-[[2-(4-propan-2-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]acetyl]piperazin-1-yl]pyridine-3-carbonitrile;2-[[2-(4-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyridin-3-yl]amino]-1-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone is sourced from PubChem (CID 159917613), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).