6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

C118H109F20N25O14S5 — CID 159926828

About 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide

6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (PubChem CID 159926828) has the molecular formula C118H109F20N25O14S5 and a molecular weight of 2641.63 g/mol. Its IUPAC name is 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

Molecular Properties

• Compound Name: 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• PubChem CID: 159926828
• Molecular Formula: C118H109F20N25O14S5
• Molecular Weight: 2641.63 g/mol
• Exact Mass: 2639.69
• IUPAC Name: 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide
• SMILES: CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn1)n2C1CCCC1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccn1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1cnccn1.Cc1ccnc(-n2c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)c(C#N)c3cc(F)c(C)cc32)n1
• InChI: InChI=1S/C25H26F4N4O3S.C25H28F4N4O3S.C23H18F4N6O2S.C23H19F4N5O3S.C22H18F4N6O3S/c1-2-14-11-20-17(12-18(14)26)21(23(30)34)22(33(20)15-5-3-4-6-15)19-8-7-16(13-31-19)37(35,36)32-24(9-10-24)25(27,28)29;1-4-14-11-20-17(12-18(14)26)21(23(30)34)22(33(20)15-7-5-6-8-15)19-10-9-16(13-31-19)37(35,36)32-24(2,3)25(27,28)29;1-12-8-20-16(9-18(12)24)17(10-28)21(33(20)22-29-7-6-13(2)31-22)19-5-4-15(11-30-19)36(34,35)32-14(3)23(25,26)27;1-12-9-18-15(10-16(12)24)20(22(28)33)21(32(18)19-5-3-4-8-29-19)17-7-6-14(11-30-17)36(34,35)31-13(2)23(25,26)27;1-11-7-17-14(8-15(11)23)19(21(27)33)20(32(17)18-10-28-5-6-29-18)16-4-3-13(9-30-16)36(34,35)31-12(2)22(24,25)26/h7-8,11-13,15,32H,2-6,9-10H2,1H3,(H2,30,34);9-13,15,32H,4-8H2,1-3H3,(H2,30,34);4-9,11,14,32H,1-3H3;3-11,13,31H,1-2H3,(H2,28,33);3-10,12,31H,1-2H3,(H2,27,33)/t;;14-;13-;12-/m..000/s1
• InChIKey: NZCVAQIKZWSAED-ZHQHTSKBSA-N
• XLogP: 21.69
• TPSA: 580.55 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 30
• Rotatable Bonds: 31
• Heavy Atoms: 182
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2641.63
LogP ≤ 5	21.69
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The IUPAC name of 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide (CID 159926828) is 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide.

What is the SMILES notation for 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The canonical SMILES for 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn1)n2C1CCCC1.CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn1)n2C1CCCC1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccn1.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1cnccn1.Cc1ccnc(-n2c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)c(C#N)c3cc(F)c(C)cc32)n1.

What is the InChIKey of 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

The InChIKey is NZCVAQIKZWSAED-ZHQHTSKBSA-N. The full InChI is InChI=1S/C25H26F4N4O3S.C25H28F4N4O3S.C23H18F4N6O2S.C23H19F4N5O3S.C22H18F4N6O3S/c1-2-14-11-20-17(12-18(14)26)21(23(30)34)22(33(20)15-5-3-4-6-15)19-8-7-16(13-31-19)37(35,36)32-24(9-10-24)25(27,28)29;1-4-14-11-20-17(12-18(14)26)21(23(30)34)22(33(20)15-7-5-6-8-15)19-10-9-16(13-31-19)37(35,36)32-24(2,3)25(27,28)29;1-12-8-20-16(9-18(12)24)17(10-28)21(33(20)22-29-7-6-13(2)31-22)19-5-4-15(11-30-19)36(34,35)32-14(3)23(25,26)27;1-12-9-18-15(10-16(12)24)20(22(28)33)21(32(18)19-5-3-4-8-29-19)17-7-6-14(11-30-17)36(34,35)31-13(2)23(25,26)27;1-11-7-17-14(8-15(11)23)19(21(27)33)20(32(17)18-10-28-5-6-29-18)16-4-3-13(9-30-16)36(34,35)31-12(2)22(24,25)26/h7-8,11-13,15,32H,2-6,9-10H2,1H3,(H2,30,34);9-13,15,32H,4-8H2,1-3H3,(H2,30,34);4-9,11,14,32H,1-3H3;3-11,13,31H,1-2H3,(H2,28,33);3-10,12,31H,1-2H3,(H2,27,33)/t;;14-;13-;12-/m..000/s1.

What are the key properties of 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide?

6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide has a molecular weight of 2641.63 g/mol, XLogP of 21.69, 31 rotatable bonds, 9 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[3-cyano-5-fluoro-6-methyl-1-(4-methylpyrimidin-2-yl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[[1-(trifluoromethyl)cyclopropyl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;1-cyclopentyl-6-ethyl-5-fluoro-2-[5-[(1,1,1-trifluoro-2-methylpropan-2-yl)sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyrazin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide;5-fluoro-6-methyl-1-pyridin-2-yl-2-[5-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]-2-pyridinyl]indole-3-carboxamide is sourced from PubChem (CID 159926828), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).