2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide

C₁₁₉H₁₂₀F₆N₃₀O₁₀ — CID 159927869

About 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide

2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide (PubChem CID 159927869) has the molecular formula C₁₁₉H₁₂₀F₆N₃₀O₁₀ and a molecular weight of 2244.46 g/mol. Its IUPAC name is 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide.

Molecular Properties

• Compound Name: 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
• PubChem CID: 159927869
• Molecular Formula: C₁₁₉H₁₂₀F₆N₃₀O₁₀
• Molecular Weight: 2244.46 g/mol
• Exact Mass: 2242.97
• IUPAC Name: 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
• SMILES: C#CC(C)(C)NC(=O)c1ncn2c(C)cc(-c3cccc(OC)n3)nc12.CCc1cc(-c2cccc(OC)n2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12.COc1cccc(-c2cc(C)n3cnc(C(=O)NC(C)(C)C4CC4)c3n2)n1.COc1cccc(-c2cc(C)n3cnc(C(=O)NC(C4CC4)C(F)(F)F)c3n2)n1.Cc1cc(-c2cccc(C#N)c2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2cccc(C#N)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12
• InChI: InChI=1S/C21H21N5O.C20H20F3N5O2.C20H23N5O2.C20H19N5O.C19H18F3N5O2.C19H19N5O2/c1-13-9-17(15-6-4-5-14(10-15)11-22)24-19-18(23-12-26(13)19)20(27)25-21(2,3)16-7-8-16;1-3-12-9-14(13-5-4-6-15(25-13)30-2)26-18-16(24-10-28(12)18)19(29)27-17(11-7-8-11)20(21,22)23;1-12-10-15(14-6-5-7-16(22-14)27-4)23-18-17(21-11-25(12)18)19(26)24-20(2,3)13-8-9-13;1-12-8-17(16-5-3-4-14(9-16)10-21)24-19-18(22-11-25(12)19)20(26)23-13(2)15-6-7-15;1-10-8-13(12-4-3-5-14(24-12)29-2)25-17-15(23-9-27(10)17)18(28)26-16(11-6-7-11)19(20,21)22;1-6-19(3,4)23-18(25)16-17-22-14(10-12(2)24(17)11-20-16)13-8-7-9-15(21-13)26-5/h4-6,9-10,12,16H,7-8H2,1-3H3,(H,25,27);4-6,9-11,17H,3,7-8H2,1-2H3,(H,27,29);5-7,10-11,13H,8-9H2,1-4H3,(H,24,26);3-5,8-9,11,13,15H,6-7H2,1-2H3,(H,23,26);3-5,8-9,11,16H,6-7H2,1-2H3,(H,26,28);1,7-11H,2-5H3,(H,23,25)/t;;;13-;;/m...0../s1
• InChIKey: NZGHROHCKMSONM-YHMBDMJUSA-N
• XLogP: 18.49
• TPSA: 491.80 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 34
• Rotatable Bonds: 28
• Heavy Atoms: 165
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2244.46
LogP ≤ 5	18.49
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	34

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?

The IUPAC name of 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide (CID 159927869) is 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide.

What is the SMILES notation for 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?

The canonical SMILES for 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide is C#CC(C)(C)NC(=O)c1ncn2c(C)cc(-c3cccc(OC)n3)nc12.CCc1cc(-c2cccc(OC)n2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12.COc1cccc(-c2cc(C)n3cnc(C(=O)NC(C)(C)C4CC4)c3n2)n1.COc1cccc(-c2cc(C)n3cnc(C(=O)NC(C4CC4)C(F)(F)F)c3n2)n1.Cc1cc(-c2cccc(C#N)c2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2cccc(C#N)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.

What is the InChIKey of 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?

The InChIKey is NZGHROHCKMSONM-YHMBDMJUSA-N. The full InChI is InChI=1S/C21H21N5O.C20H20F3N5O2.C20H23N5O2.C20H19N5O.C19H18F3N5O2.C19H19N5O2/c1-13-9-17(15-6-4-5-14(10-15)11-22)24-19-18(23-12-26(13)19)20(27)25-21(2,3)16-7-8-16;1-3-12-9-14(13-5-4-6-15(25-13)30-2)26-18-16(24-10-28(12)18)19(29)27-17(11-7-8-11)20(21,22)23;1-12-10-15(14-6-5-7-16(22-14)27-4)23-18-17(21-11-25(12)18)19(26)24-20(2,3)13-8-9-13;1-12-8-17(16-5-3-4-14(9-16)10-21)24-19-18(22-11-25(12)19)20(26)23-13(2)15-6-7-15;1-10-8-13(12-4-3-5-14(24-12)29-2)25-17-15(23-9-27(10)17)18(28)26-16(11-6-7-11)19(20,21)22;1-6-19(3,4)23-18(25)16-17-22-14(10-12(2)24(17)11-20-16)13-8-7-9-15(21-13)26-5/h4-6,9-10,12,16H,7-8H2,1-3H3,(H,25,27);4-6,9-11,17H,3,7-8H2,1-2H3,(H,27,29);5-7,10-11,13H,8-9H2,1-4H3,(H,24,26);3-5,8-9,11,13,15H,6-7H2,1-2H3,(H,23,26);3-5,8-9,11,16H,6-7H2,1-2H3,(H,26,28);1,7-11H,2-5H3,(H,23,25)/t;;;13-;;/m...0../s1.

What are the key properties of 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?

2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide has a molecular weight of 2244.46 g/mol, XLogP of 18.49, 28 rotatable bonds, 6 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(3-cyanophenyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-cyanophenyl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(6-methoxy-2-pyridinyl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(6-methoxy-2-pyridinyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-methoxy-2-pyridinyl)-4-methyl-N-(2-methylbut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 159927869), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 159927869 — identifiers, structure, computed properties (public domain)

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