N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

C111H126F2N28O12S2 — CID 159963853

About N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (PubChem CID 159963853) has the molecular formula C111H126F2N28O12S2 and a molecular weight of 2146.54 g/mol. Its IUPAC name is N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• PubChem CID: 159963853
• Molecular Formula: C111H126F2N28O12S2
• Molecular Weight: 2146.54 g/mol
• Exact Mass: 2144.95
• IUPAC Name: N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• SMILES: O=C(Nc1cc(N2CCOCC2)ccc1N1CCCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1csc(-c2cn[nH]c2)n1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCCC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCCC1)c1csc(-c2cn[nH]c2)n1
• InChI: InChI=1S/C23H26N6O2.C23H27N5O3.C22H24F2N6O2S.C22H25N5O3.C21H24N6O2S/c30-23(21-5-3-4-19(26-21)17-15-24-25-16-17)27-20-7-6-18(28-10-12-31-13-11-28)14-22(20)29-8-1-2-9-29;29-23(22-7-6-21(31-22)17-15-24-25-16-17)26-19-14-18(27-10-12-30-13-11-27)4-5-20(19)28-8-2-1-3-9-28;23-22(24)3-5-30(6-4-22)19-11-16(29-7-9-32-10-8-29)1-2-17(19)27-20(31)18-14-33-21(28-18)15-12-25-26-13-15;28-22(21-6-5-20(30-21)16-14-23-24-15-16)25-18-4-3-17(26-9-11-29-12-10-26)13-19(18)27-7-1-2-8-27;28-20(18-14-30-21(25-18)15-12-22-23-13-15)24-17-4-3-16(26-7-9-29-10-8-26)11-19(17)27-5-1-2-6-27/h3-7,14-16H,1-2,8-13H2,(H,24,25)(H,27,30);4-7,14-16H,1-3,8-13H2,(H,24,25)(H,26,29);1-2,11-14H,3-10H2,(H,25,26)(H,27,31);3-6,13-15H,1-2,7-12H2,(H,23,24)(H,25,28);3-4,11-14H,1-2,5-10H2,(H,22,23)(H,24,28)
• InChIKey: ODRDLYBSVKTRGX-UHFFFAOYSA-N
• XLogP: 17.35
• TPSA: 432.40 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 32
• Rotatable Bonds: 25
• Heavy Atoms: 155
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2146.54
LogP ≤ 5	17.35
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	32

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The IUPAC name of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (CID 159963853) is N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

What is the SMILES notation for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The canonical SMILES for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is O=C(Nc1cc(N2CCOCC2)ccc1N1CCCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1csc(-c2cn[nH]c2)n1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCCC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCCC1)c1csc(-c2cn[nH]c2)n1.

What is the InChIKey of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The InChIKey is ODRDLYBSVKTRGX-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H26N6O2.C23H27N5O3.C22H24F2N6O2S.C22H25N5O3.C21H24N6O2S/c30-23(21-5-3-4-19(26-21)17-15-24-25-16-17)27-20-7-6-18(28-10-12-31-13-11-28)14-22(20)29-8-1-2-9-29;29-23(22-7-6-21(31-22)17-15-24-25-16-17)26-19-14-18(27-10-12-30-13-11-27)4-5-20(19)28-8-2-1-3-9-28;23-22(24)3-5-30(6-4-22)19-11-16(29-7-9-32-10-8-29)1-2-17(19)27-20(31)18-14-33-21(28-18)15-12-25-26-13-15;28-22(21-6-5-20(30-21)16-14-23-24-15-16)25-18-4-3-17(26-9-11-29-12-10-26)13-19(18)27-7-1-2-8-27;28-20(18-14-30-21(25-18)15-12-22-23-13-15)24-17-4-3-16(26-7-9-29-10-8-26)11-19(17)27-5-1-2-6-27/h3-7,14-16H,1-2,8-13H2,(H,24,25)(H,27,30);4-7,14-16H,1-3,8-13H2,(H,24,25)(H,26,29);1-2,11-14H,3-10H2,(H,25,26)(H,27,31);3-6,13-15H,1-2,7-12H2,(H,23,24)(H,25,28);3-4,11-14H,1-2,5-10H2,(H,22,23)(H,24,28).

What are the key properties of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide has a molecular weight of 2146.54 g/mol, XLogP of 17.35, 25 rotatable bonds, 10 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-(5-morpholin-4-yl-2-piperidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(4-morpholin-4-yl-2-pyrrolidin-1-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 159963853), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).