N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide

C88H75ClF5N15O15S10 — CID 160538819

IUPACN-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide
SMILESCc1ccc(CS(=O)(=O)c2cnc(NC(=O)c3ccccn3)s2)c(Cl)c1.Cc1ccc(CS(=O)(=O)c2cnc(NC(=O)c3ccccn3)s2)c(F)c1.Cc1ccc(CS(=O)(=O)c2sc(NC(=O)c3ccccn3)nc2C(F)F)c(F)c1.Cc1nc(NC(=O)c2ccccn2)sc1S(=O)(=O)Cc1ccc(C(C)C)cc1.O=C(Nc1ncc(S(=O)(=O)Cc2ccccc2F)s1)c1ccccn1
InChIInChI=1S/C20H21N3O3S2.C18H14F3N3O3S2.C17H14ClN3O3S2.C17H14FN3O3S2.C16H12FN3O3S2/c1-13(2)16-9-7-15(8-10-16)12-28(25,26)19-14(3)22-20(27-19)23-18(24)17-6-4-5-11-21-17;1-10-5-6-11(12(19)8-10)9-29(26,27)17-14(15(20)21)23-18(28-17)24-16(25)13-4-2-3-7-22-13;2*1-11-5-6-12(13(18)8-11)10-26(23,24)15-9-20-17(25-15)21-16(22)14-4-2-3-7-19-14;17-12-6-2-1-5-11(12)10-25(22,23)14-9-19-16(24-14)20-15(21)13-7-3-4-8-18-13/h4-11,13H,12H2,1-3H3,(H,22,23,24);2-8,15H,9H2,1H3,(H,23,24,25);2*2-9H,10H2,1H3,(H,20,21,22);1-9H,10H2,(H,19,20,21)
InChIKeyQWMSKDNHCQXZJH-UHFFFAOYSA-N
MW2033.77 g/mol
LogP18.19
Rot. Bonds27

About N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide

N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide (PubChem CID 160538819) has the molecular formula C88H75ClF5N15O15S10 and a molecular weight of 2033.77 g/mol. Its IUPAC name is N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide.

Molecular Properties

Compound NameN-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide
PubChem CID160538819
Molecular FormulaC88H75ClF5N15O15S10
Molecular Weight2033.77 g/mol
Exact Mass2031.24
IUPAC NameN-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide
SMILESCc1ccc(CS(=O)(=O)c2cnc(NC(=O)c3ccccn3)s2)c(Cl)c1.Cc1ccc(CS(=O)(=O)c2cnc(NC(=O)c3ccccn3)s2)c(F)c1.Cc1ccc(CS(=O)(=O)c2sc(NC(=O)c3ccccn3)nc2C(F)F)c(F)c1.Cc1nc(NC(=O)c2ccccn2)sc1S(=O)(=O)Cc1ccc(C(C)C)cc1.O=C(Nc1ncc(S(=O)(=O)Cc2ccccc2F)s1)c1ccccn1
InChIInChI=1S/C20H21N3O3S2.C18H14F3N3O3S2.C17H14ClN3O3S2.C17H14FN3O3S2.C16H12FN3O3S2/c1-13(2)16-9-7-15(8-10-16)12-28(25,26)19-14(3)22-20(27-19)23-18(24)17-6-4-5-11-21-17;1-10-5-6-11(12(19)8-10)9-29(26,27)17-14(15(20)21)23-18(28-17)24-16(25)13-4-2-3-7-22-13;2*1-11-5-6-12(13(18)8-11)10-26(23,24)15-9-20-17(25-15)21-16(22)14-4-2-3-7-19-14;17-12-6-2-1-5-11(12)10-25(22,23)14-9-19-16(24-14)20-15(21)13-7-3-4-8-18-13/h4-11,13H,12H2,1-3H3,(H,22,23,24);2-8,15H,9H2,1H3,(H,23,24,25);2*2-9H,10H2,1H3,(H,20,21,22);1-9H,10H2,(H,19,20,21)
InChIKeyQWMSKDNHCQXZJH-UHFFFAOYSA-N
XLogP18.19
TPSA445.10 Ų
H-Bond Donors5
H-Bond Acceptors30
Rotatable Bonds27
Heavy Atoms134
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002033.77
LogP ≤ 518.19
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1030

Analyze N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[5-[(3-chlorophenyl)methylsulfonyl]-4-methyl-1,3-thiazol-2-yl]pyridine-2-carboxamide
CID 88889458
N-[5-[(2,6-difluorophenyl)methylsulfonyl]-4-(fluoromethyl)-1,3-thiazol-2-yl]pyridine-2-carboxamide
CID 54670324
5-[(2-chlorophenyl)methylsulfonyl]-4-methyl-N-(pyridin-2-ylmethyl)-1,3-thiazol-2-amine
CID 123661730
(2-chlorophenyl)methyl 4-methyl-2-(pyridine-2-carbonylamino)-1,3-thiazole-5-sulfonate
CID 174685813
N-[4-cyclopropyl-5-[(2,6-difluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide
CID 54670690
N-[5-[(2,4-dichlorophenyl)methyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide
CID 24628775
N-[5,6-dimethyl-7-[(4-propan-2-ylphenyl)methylsulfonyl]-4,5-dihydrothiepin-2-yl]pyridine-2-carboxamide
CID 123508185
N-[5-[1-[(2,6-difluorophenyl)methyl]-2,3-dioxocyclopropyl]-4-propan-2-yl-1,3-thiazol-2-yl]pyridine-2-carboxamide
CID 123810250
2-chloro-4-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)benzamide
CID 106861734
2-[(2-fluorobenzoyl)amino]-4-methyl-1,3-thiazole-5-sulfonyl chloride
CID 63945041
4-N-[(2-fluorophenyl)methyl]-2-N-(4-propan-2-ylphenyl)pyridine-2,4-dicarboxamide
CID 109086373
2-(2-chloro-6-fluorophenyl)-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide
CID 22170794

Frequently Asked Questions

What is the IUPAC name of N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide?
The IUPAC name of N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide (CID 160538819) is N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide.
What is the SMILES notation for N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide?
The canonical SMILES for N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide is Cc1ccc(CS(=O)(=O)c2cnc(NC(=O)c3ccccn3)s2)c(Cl)c1.Cc1ccc(CS(=O)(=O)c2cnc(NC(=O)c3ccccn3)s2)c(F)c1.Cc1ccc(CS(=O)(=O)c2sc(NC(=O)c3ccccn3)nc2C(F)F)c(F)c1.Cc1nc(NC(=O)c2ccccn2)sc1S(=O)(=O)Cc1ccc(C(C)C)cc1.O=C(Nc1ncc(S(=O)(=O)Cc2ccccc2F)s1)c1ccccn1.
What is the InChIKey of N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide?
The InChIKey is QWMSKDNHCQXZJH-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H21N3O3S2.C18H14F3N3O3S2.C17H14ClN3O3S2.C17H14FN3O3S2.C16H12FN3O3S2/c1-13(2)16-9-7-15(8-10-16)12-28(25,26)19-14(3)22-20(27-19)23-18(24)17-6-4-5-11-21-17;1-10-5-6-11(12(19)8-10)9-29(26,27)17-14(15(20)21)23-18(28-17)24-16(25)13-4-2-3-7-22-13;2*1-11-5-6-12(13(18)8-11)10-26(23,24)15-9-20-17(25-15)21-16(22)14-4-2-3-7-19-14;17-12-6-2-1-5-11(12)10-25(22,23)14-9-19-16(24-14)20-15(21)13-7-3-4-8-18-13/h4-11,13H,12H2,1-3H3,(H,22,23,24);2-8,15H,9H2,1H3,(H,23,24,25);2*2-9H,10H2,1H3,(H,20,21,22);1-9H,10H2,(H,19,20,21).
What are the key properties of N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide?
N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide has a molecular weight of 2033.77 g/mol, XLogP of 18.19, 27 rotatable bonds, 5 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[(2-chloro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-(difluoromethyl)-5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluoro-4-methylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[5-[(2-fluorophenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide;N-[4-methyl-5-[(4-propan-2-ylphenyl)methylsulfonyl]-1,3-thiazol-2-yl]pyridine-2-carboxamide is sourced from PubChem (CID 160538819), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).