2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide

C136H132Cl4F15N27O12S6 — CID 160590653

About 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide

2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide (PubChem CID 160590653) has the molecular formula C136H132Cl4F15N27O12S6 and a molecular weight of 2955.91 g/mol. Its IUPAC name is 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide
• PubChem CID: 160590653
• Molecular Formula: C136H132Cl4F15N27O12S6
• Molecular Weight: 2955.91 g/mol
• Exact Mass: 2951.74
• IUPAC Name: 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide
• SMILES: CC(C)c1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(CC3CC3)c2c1.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1cnc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCCCC2)nc1)C(F)(F)F.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCCC2)c2ccc(Cl)cc12.N#Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(C3CCC3)c2c1
• InChI: InChI=1S/C24H26F2N4O2S.2C23H22ClF3N4O2S.C22H21ClF3N5O2S.C22H22ClF2N5O2S.C22H19F2N5O2S/c1-15(2)17-5-7-20-21(12-27)24(30(23(20)9-17)14-16-3-4-16)22-8-6-19(13-28-22)33(31,32)29-18(10-25)11-26;2*1-14(23(25,26)27)30-34(32,33)17-8-9-20(29-13-17)22-19(12-28)18-11-15(24)7-10-21(18)31(22)16-5-3-2-4-6-16;1-13(22(24,25)26)30-34(32,33)16-11-28-21(29-12-16)20-18(10-27)17-9-14(23)7-8-19(17)31(20)15-5-3-2-4-6-15;23-14-6-7-20-18(8-14)19(11-26)21(30(20)16-4-2-1-3-5-16)22-27-12-17(13-28-22)33(31,32)29-15(9-24)10-25;23-9-15(10-24)28-32(30,31)17-5-7-20(27-13-17)22-19(12-26)18-6-4-14(11-25)8-21(18)29(22)16-2-1-3-16/h5-9,13,15-16,18,29H,3-4,10-11,14H2,1-2H3;2*7-11,13-14,16,30H,2-6H2,1H3;7-9,11-13,15,30H,2-6H2,1H3;6-8,12-13,15-16,29H,1-5,9-10H2;4-8,13,15-16,28H,1-3,9-10H2/t;2*14-;13-;;/m.100../s1
• InChIKey: RCYRWJCXRMANDL-VVWCSOPHSA-N
• XLogP: 30.45
• TPSA: 576.25 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 33
• Rotatable Bonds: 38
• Heavy Atoms: 200
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2955.91
LogP ≤ 5	30.45
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

The IUPAC name of 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide (CID 160590653) is 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide.

What is the SMILES notation for 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

The canonical SMILES for 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide is CC(C)c1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(CC3CC3)c2c1.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1cnc(-c2c(C#N)c3cc(Cl)ccc3n2C2CCCCC2)nc1)C(F)(F)F.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCCC2)c2ccc(Cl)cc12.N#Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(C3CCC3)c2c1.

What is the InChIKey of 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

The InChIKey is RCYRWJCXRMANDL-VVWCSOPHSA-N. The full InChI is InChI=1S/C24H26F2N4O2S.2C23H22ClF3N4O2S.C22H21ClF3N5O2S.C22H22ClF2N5O2S.C22H19F2N5O2S/c1-15(2)17-5-7-20-21(12-27)24(30(23(20)9-17)14-16-3-4-16)22-8-6-19(13-28-22)33(31,32)29-18(10-25)11-26;2*1-14(23(25,26)27)30-34(32,33)17-8-9-20(29-13-17)22-19(12-28)18-11-15(24)7-10-21(18)31(22)16-5-3-2-4-6-16;1-13(22(24,25)26)30-34(32,33)16-11-28-21(29-12-16)20-18(10-27)17-9-14(23)7-8-19(17)31(20)15-5-3-2-4-6-15;23-14-6-7-20-18(8-14)19(11-26)21(30(20)16-4-2-1-3-5-16)22-27-12-17(13-28-22)33(31,32)29-15(9-24)10-25;23-9-15(10-24)28-32(30,31)17-5-7-20(27-13-17)22-19(12-26)18-6-4-14(11-25)8-21(18)29(22)16-2-1-3-16/h5-9,13,15-16,18,29H,3-4,10-11,14H2,1-2H3;2*7-11,13-14,16,30H,2-6H2,1H3;7-9,11-13,15,30H,2-6H2,1H3;6-8,12-13,15-16,29H,1-5,9-10H2;4-8,13,15-16,28H,1-3,9-10H2/t;2*14-;13-;;/m.100../s1.

What are the key properties of 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide has a molecular weight of 2955.91 g/mol, XLogP of 30.45, 38 rotatable bonds, 6 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-(5-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-propan-2-ylindol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3,6-dicyano-1-cyclobutylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide is sourced from PubChem (CID 160590653), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).