5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide

C93H81F2N19O11 — CID 161144357

About 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide

5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide (PubChem CID 161144357) has the molecular formula C93H81F2N19O11 and a molecular weight of 1678.79 g/mol. Its IUPAC name is 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide.

Molecular Properties

• Compound Name: 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide
• PubChem CID: 161144357
• Molecular Formula: C93H81F2N19O11
• Molecular Weight: 1678.79 g/mol
• Exact Mass: 1677.63
• IUPAC Name: 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide
• SMILES: Nc1cncc(-c2ccc3[nH]nc(C(=O)Nc4ccc5c(c4)OCCO5)c3c2)c1.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cccnc3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.O=C(Nc1ccccc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12
• InChI: InChI=1S/C26H23F2N5O3.C25H25N5O2.C21H17N5O3.C21H16N4O3/c27-26(28)5-6-33(15-26)14-16-9-18(13-29-12-16)17-1-3-21-20(10-17)24(32-31-21)25(34)30-19-2-4-22-23(11-19)36-8-7-35-22;31-21-8-10-30(11-9-21)16-17-12-19(15-26-14-17)18-6-7-23-22(13-18)24(29-28-23)25(32)27-20-4-2-1-3-5-20;22-14-7-13(10-23-11-14)12-1-3-17-16(8-12)20(26-25-17)21(27)24-15-2-4-18-19(9-15)29-6-5-28-18;26-21(23-15-4-6-18-19(11-15)28-9-8-27-18)20-16-10-13(3-5-17(16)24-25-20)14-2-1-7-22-12-14/h1-4,9-13H,5-8,14-15H2,(H,30,34)(H,31,32);1-7,12-15,21,31H,8-11,16H2,(H,27,32)(H,28,29);1-4,7-11H,5-6,22H2,(H,24,27)(H,25,26);1-7,10-12H,8-9H2,(H,23,26)(H,24,25)
• InChIKey: UNVVELJKKVWLGR-UHFFFAOYSA-N
• XLogP: 15.20
• TPSA: 390.79 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 22
• Rotatable Bonds: 16
• Heavy Atoms: 125
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1678.79
LogP ≤ 5	15.20
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	22

Frequently Asked Questions

What is the IUPAC name of 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide?

The IUPAC name of 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide (CID 161144357) is 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide.

What is the SMILES notation for 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide?

The canonical SMILES for 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide is Nc1cncc(-c2ccc3[nH]nc(C(=O)Nc4ccc5c(c4)OCCO5)c3c2)c1.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cccnc3)cc12.O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.O=C(Nc1ccccc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(O)CC4)c3)cc12.

What is the InChIKey of 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide?

The InChIKey is UNVVELJKKVWLGR-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H23F2N5O3.C25H25N5O2.C21H17N5O3.C21H16N4O3/c27-26(28)5-6-33(15-26)14-16-9-18(13-29-12-16)17-1-3-21-20(10-17)24(32-31-21)25(34)30-19-2-4-22-23(11-19)36-8-7-35-22;31-21-8-10-30(11-9-21)16-17-12-19(15-26-14-17)18-6-7-23-22(13-18)24(29-28-23)25(32)27-20-4-2-1-3-5-20;22-14-7-13(10-23-11-14)12-1-3-17-16(8-12)20(26-25-17)21(27)24-15-2-4-18-19(9-15)29-6-5-28-18;26-21(23-15-4-6-18-19(11-15)28-9-8-27-18)20-16-10-13(3-5-17(16)24-25-20)14-2-1-7-22-12-14/h1-4,9-13H,5-8,14-15H2,(H,30,34)(H,31,32);1-7,12-15,21,31H,8-11,16H2,(H,27,32)(H,28,29);1-4,7-11H,5-6,22H2,(H,24,27)(H,25,26);1-7,10-12H,8-9H2,(H,23,26)(H,24,25).

What are the key properties of 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide?

5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide has a molecular weight of 1678.79 g/mol, XLogP of 15.20, 16 rotatable bonds, 10 hydrogen bond donors, and 22 hydrogen bond acceptors.

Where does this data come from?

All data for 5-(5-amino-3-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-indazole-3-carboxamide;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-3-yl-1H-indazole-3-carboxamide;5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-N-phenyl-1H-indazole-3-carboxamide is sourced from PubChem (CID 161144357), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).