2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone

C190H210F11N27O28S — CID 161167542

IUPAC2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone
SMILESCc1ccc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2cnnc(C(F)(F)F)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(OC(F)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(S(C)(=O)=O)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1
InChIInChI=1S/C30H35F3N4O3.C30H34N4O3.C27H28F3N3O4.C27H32N4O5.C27H31N3O5S.C25H26F2N4O4.C24H24F3N5O4/c1-18(2)40-28-26(37-6-8-39-9-7-37)14-21(16-36-28)25-13-22(17-35-19(25)3)27(38)12-20-10-23(29(4,5)34)15-24(11-20)30(31,32)33;1-20(2)37-29-27(34-9-11-36-12-10-34)16-23(17-33-29)26-15-24(18-32-21(26)3)28(35)14-22-7-6-8-25(13-22)30(4,5)19-31;1-17(2)36-26-24(33-7-9-35-10-8-33)14-20(15-32-26)23-13-21(16-31-18(23)3)25(34)12-19-5-4-6-22(11-19)37-27(28,29)30;1-18-4-5-21(30-25(33)19-6-7-28-24(15-19)27(2,3)34)16-22(18)20-14-23(31-8-11-35-12-9-31)26(29-17-20)36-13-10-32;1-18(2)35-27-25(30-8-10-34-11-9-30)15-21(16-29-27)24-14-22(17-28-19(24)3)26(31)13-20-6-5-7-23(12-20)36(4,32)33;1-16-2-3-19(30-24(33)17-4-5-28-21(12-17)23(26)27)14-20(16)18-13-22(31-6-9-34-10-7-31)25(29-15-18)35-11-8-32;1-15-2-3-18(30-22(34)17-11-21(24(25,26)27)31-29-14-17)12-19(15)16-10-20(32-4-7-35-8-5-32)23(28-13-16)36-9-6-33/h10-11,13-18H,6-9,12,34H2,1-5H3;6-8,13,15-18,20H,9-12,14H2,1-5H3;4-6,11,13-17H,7-10,12H2,1-3H3;4-7,14-17,32,34H,8-13H2,1-3H3,(H,30,33);5-7,12,14-18H,8-11,13H2,1-4H3;2-5,12-15,23,32H,6-11H2,1H3,(H,30,33);2-3,10-14,33H,4-9H2,1H3,(H,30,34)
InChIKeyUQTAWUDPBRQOFX-UHFFFAOYSA-N
MW3560.98 g/mol
LogP30.64
Rot. Bonds55

About 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone

2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone (PubChem CID 161167542) has the molecular formula C190H210F11N27O28S and a molecular weight of 3560.98 g/mol. Its IUPAC name is 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone.

Molecular Properties

Compound Name2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone
PubChem CID161167542
Molecular FormulaC190H210F11N27O28S
Molecular Weight3560.98 g/mol
Exact Mass3558.54
IUPAC Name2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone
SMILESCc1ccc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2cnnc(C(F)(F)F)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(OC(F)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(S(C)(=O)=O)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1
InChIInChI=1S/C30H35F3N4O3.C30H34N4O3.C27H28F3N3O4.C27H32N4O5.C27H31N3O5S.C25H26F2N4O4.C24H24F3N5O4/c1-18(2)40-28-26(37-6-8-39-9-7-37)14-21(16-36-28)25-13-22(17-35-19(25)3)27(38)12-20-10-23(29(4,5)34)15-24(11-20)30(31,32)33;1-20(2)37-29-27(34-9-11-36-12-10-34)16-23(17-33-29)26-15-24(18-32-21(26)3)28(35)14-22-7-6-8-25(13-22)30(4,5)19-31;1-17(2)36-26-24(33-7-9-35-10-8-33)14-20(15-32-26)23-13-21(16-31-18(23)3)25(34)12-19-5-4-6-22(11-19)37-27(28,29)30;1-18-4-5-21(30-25(33)19-6-7-28-24(15-19)27(2,3)34)16-22(18)20-14-23(31-8-11-35-12-9-31)26(29-17-20)36-13-10-32;1-18(2)35-27-25(30-8-10-34-11-9-30)15-21(16-29-27)24-14-22(17-28-19(24)3)26(31)13-20-6-5-7-23(12-20)36(4,32)33;1-16-2-3-19(30-24(33)17-4-5-28-21(12-17)23(26)27)14-20(16)18-13-22(31-6-9-34-10-7-31)25(29-15-18)35-11-8-32;1-15-2-3-18(30-22(34)17-11-21(24(25,26)27)31-29-14-17)12-19(15)16-10-20(32-4-7-35-8-5-32)23(28-13-16)36-9-6-33/h10-11,13-18H,6-9,12,34H2,1-5H3;6-8,13,15-18,20H,9-12,14H2,1-5H3;4-6,11,13-17H,7-10,12H2,1-3H3;4-7,14-17,32,34H,8-13H2,1-3H3,(H,30,33);5-7,12,14-18H,8-11,13H2,1-4H3;2-5,12-15,23,32H,6-11H2,1H3,(H,30,33);2-3,10-14,33H,4-9H2,1H3,(H,30,34)
InChIKeyUQTAWUDPBRQOFX-UHFFFAOYSA-N
XLogP30.64
TPSA674.93 Ų
H-Bond Donors8
H-Bond Acceptors52
Rotatable Bonds55
Heavy Atoms257
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003560.98
LogP ≤ 530.64
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1052

Analyze 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone with MolForge

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Launch Full Analysis

Related Compounds

2-(1,1-difluoroethyl)-N-[3-[6-[2-[4-[3-ethoxy-6-[2-methyl-5-[(3-methylsulfonylbenzoyl)amino]phenyl]pyridazin-4-yl]morpholin-2-yl]ethoxy]-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425814
5-ethoxy-N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;bis(N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide);1-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-(2-methylsulfonyl-4-pyridinyl)ethanone;2-[4-[2-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-oxoethyl]-2-pyridinyl]-2-methylpropanenitrile;[[4-[2-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-oxoethyl]-2-pyridinyl]-dimethyl-lambda4-sulfanyl]formonitrile
CID 157095397
2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157268806
2-(2-cyanopropan-2-yl)-N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;1-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-[3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl]ethanone;1-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-[3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl]ethanone;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[6-methyl-5-[6-(1-methylpiperidin-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157397421
N-[5-[6-(1-acetylpiperidin-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-[3-(difluoromethoxy)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;1-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-[3-(trifluoromethyl)phenyl]ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone;N-[4-methyl-3-[2-morpholin-4-yl-6-(2-pyrrolidin-1-ylethoxy)-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157562317
6-(2-cyanopropan-2-yl)-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]-3-pyridinyl]pyridazine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-methylsulfonylbenzamide
CID 158203361
2-ethoxy-N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;bis(N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide);1-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-(2-methylsulfonyl-4-pyridinyl)ethanone;2-[4-[2-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-oxoethyl]-2-pyridinyl]-2-methylpropanenitrile;2-[4-[2-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-oxoethyl]-2-pyridinyl]-2-methylpropanenitrile
CID 158380378
6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide
CID 158481617
4-butyl-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3S)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[5-[6-ethoxy-5-[(3S)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-4-propyl-3-(trifluoromethyl)benzamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide
CID 158641862
2-(2-cyanopropan-2-yl)-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;6-cyclopropyl-N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]phenyl]pyridazine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]pyridine-4-carboxamide;N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]phenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide
CID 158739967
2-(2-cyanopropan-2-yl)-N-[5-[3-(3-fluorooxetan-3-yl)-5-(3-hydroxyoxetan-3-yl)phenyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-[3-(3-fluorooxetan-3-yl)-5-(3-hydroxyoxetan-3-yl)phenyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[2-(2-hydroxyethoxy)-6-(3-methoxyoxetan-3-yl)-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[5-(3-hydroxyoxetan-3-yl)-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[6-ethoxy-5-[3-(fluoromethyl)oxetan-3-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[5-[3-(3-fluorooxetan-3-yl)-5-(3-hydroxyoxetan-3-yl)phenyl]-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;1-[3-[5-(3-hydroxyoxetan-3-yl)-6-methoxy-3-pyridinyl]-4-methylphenyl]-2-(2-methylsulfonyl-4-pyridinyl)ethanone
CID 159306868
2-cyclopropyl-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]benzamide;2-(difluoromethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-3-methylsulfonylbenzamide
CID 159463604

Frequently Asked Questions

What is the IUPAC name of 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone?
The IUPAC name of 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone (CID 161167542) is 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone.
What is the SMILES notation for 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone?
The canonical SMILES for 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone is Cc1ccc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ccc(NC(=O)c2cnnc(C(F)(F)F)c2)cc1-c1cnc(OCCO)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(OC(F)(F)F)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.Cc1ncc(C(=O)Cc2cccc(S(C)(=O)=O)c2)cc1-c1cnc(OC(C)C)c(N2CCOCC2)c1.
What is the InChIKey of 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone?
The InChIKey is UQTAWUDPBRQOFX-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H35F3N4O3.C30H34N4O3.C27H28F3N3O4.C27H32N4O5.C27H31N3O5S.C25H26F2N4O4.C24H24F3N5O4/c1-18(2)40-28-26(37-6-8-39-9-7-37)14-21(16-36-28)25-13-22(17-35-19(25)3)27(38)12-20-10-23(29(4,5)34)15-24(11-20)30(31,32)33;1-20(2)37-29-27(34-9-11-36-12-10-34)16-23(17-33-29)26-15-24(18-32-21(26)3)28(35)14-22-7-6-8-25(13-22)30(4,5)19-31;1-17(2)36-26-24(33-7-9-35-10-8-33)14-20(15-32-26)23-13-21(16-31-18(23)3)25(34)12-19-5-4-6-22(11-19)37-27(28,29)30;1-18-4-5-21(30-25(33)19-6-7-28-24(15-19)27(2,3)34)16-22(18)20-14-23(31-8-11-35-12-9-31)26(29-17-20)36-13-10-32;1-18(2)35-27-25(30-8-10-34-11-9-30)15-21(16-29-27)24-14-22(17-28-19(24)3)26(31)13-20-6-5-7-23(12-20)36(4,32)33;1-16-2-3-19(30-24(33)17-4-5-28-21(12-17)23(26)27)14-20(16)18-13-22(31-6-9-34-10-7-31)25(29-15-18)35-11-8-32;1-15-2-3-18(30-22(34)17-11-21(24(25,26)27)31-29-14-17)12-19(15)16-10-20(32-4-7-35-8-5-32)23(28-13-16)36-9-6-33/h10-11,13-18H,6-9,12,34H2,1-5H3;6-8,13,15-18,20H,9-12,14H2,1-5H3;4-6,11,13-17H,7-10,12H2,1-3H3;4-7,14-17,32,34H,8-13H2,1-3H3,(H,30,33);5-7,12,14-18H,8-11,13H2,1-4H3;2-5,12-15,23,32H,6-11H2,1H3,(H,30,33);2-3,10-14,33H,4-9H2,1H3,(H,30,34).
What are the key properties of 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone?
2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone has a molecular weight of 3560.98 g/mol, XLogP of 30.64, 55 rotatable bonds, 8 hydrogen bond donors, and 52 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;2-(difluoromethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(2-hydroxypropan-2-yl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;2-methyl-2-[3-[2-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-oxoethyl]phenyl]propanenitrile;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone is sourced from PubChem (CID 161167542), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).