6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile

C68H79FN18O2S4 — CID 161236494

IUPAC6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile
SMILESCc1cn2cc(-c3cc4sc(OC5CC(C)(C)NC(C)(C)C5)nc4cn3)cc(C#N)c2n1.Cc1cn2cc(-c3cc4sc(OC5CC(C)(C)NC(C)(C)C5)nc4cn3)cc(F)c2n1.Cc1nn2cc(-c3cc4sc(N(C)C5CC(C)(C)NC(C)(C)C5)nc4cn3)nc2s1
InChIInChI=1S/C24H26N6OS.C23H26FN5OS.C21H27N7S2/c1-14-12-30-13-16(6-15(10-25)21(30)27-14)18-7-20-19(11-26-18)28-22(32-20)31-17-8-23(2,3)29-24(4,5)9-17;1-13-11-29-12-14(6-16(24)20(29)26-13)17-7-19-18(10-25-17)27-21(31-19)30-15-8-22(2,3)28-23(4,5)9-15;1-12-25-28-11-16(24-19(28)29-12)14-7-17-15(10-22-14)23-18(30-17)27(6)13-8-20(2,3)26-21(4,5)9-13/h6-7,11-13,17,29H,8-9H2,1-5H3;6-7,10-12,15,28H,8-9H2,1-5H3;7,10-11,13,26H,8-9H2,1-6H3
InChIKeyUZKZFHCOJRMCBK-UHFFFAOYSA-N
MW1327.77 g/mol
LogP14.53
Rot. Bonds9

About 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile

6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile (PubChem CID 161236494) has the molecular formula C68H79FN18O2S4 and a molecular weight of 1327.77 g/mol. Its IUPAC name is 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile.

Molecular Properties

Compound Name6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile
PubChem CID161236494
Molecular FormulaC68H79FN18O2S4
Molecular Weight1327.77 g/mol
Exact Mass1326.55
IUPAC Name6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile
SMILESCc1cn2cc(-c3cc4sc(OC5CC(C)(C)NC(C)(C)C5)nc4cn3)cc(C#N)c2n1.Cc1cn2cc(-c3cc4sc(OC5CC(C)(C)NC(C)(C)C5)nc4cn3)cc(F)c2n1.Cc1nn2cc(-c3cc4sc(N(C)C5CC(C)(C)NC(C)(C)C5)nc4cn3)nc2s1
InChIInChI=1S/C24H26N6OS.C23H26FN5OS.C21H27N7S2/c1-14-12-30-13-16(6-15(10-25)21(30)27-14)18-7-20-19(11-26-18)28-22(32-20)31-17-8-23(2,3)29-24(4,5)9-17;1-13-11-29-12-14(6-16(24)20(29)26-13)17-7-19-18(10-25-17)27-21(31-19)30-15-8-22(2,3)28-23(4,5)9-15;1-12-25-28-11-16(24-19(28)29-12)14-7-17-15(10-22-14)23-18(30-17)27(6)13-8-20(2,3)26-21(4,5)9-13/h6-7,11-13,17,29H,8-9H2,1-5H3;6-7,10-12,15,28H,8-9H2,1-5H3;7,10-11,13,26H,8-9H2,1-6H3
InChIKeyUZKZFHCOJRMCBK-UHFFFAOYSA-N
XLogP14.53
TPSA223.71 Ų
H-Bond Donors3
H-Bond Acceptors24
Rotatable Bonds9
Heavy Atoms93
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001327.77
LogP ≤ 514.53
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1024

Analyze 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile with MolForge

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Related Compounds

N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine
CID 151617655
2-methyl-6-[2-[methyl(piperidin-4-yl)amino]-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile;hydrochloride
CID 153383364
5-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[5,4-b]pyridin-2-amine
CID 151923812
6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-piperidin-4-yloxy-[1,3]thiazolo[4,5-c]pyridine;hydrochloride
CID 153383026
6-(7-fluoro-2-methylindazol-5-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;6-[4-fluoro-2-[methyl(piperidin-4-yl)amino]-1,3-benzothiazol-6-yl]-2-methylimidazo[1,2-b]pyridazine-8-carbonitrile;6-(4-fluoro-2-piperidin-4-yl-1,3-benzothiazol-6-yl)-2-methylimidazo[1,2-b]pyridazine-8-carbonitrile
CID 159909962
6-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-b]pyrazin-2-amine
CID 160920826
2-[2-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-[1,3]thiazolo[4,5-c]pyridin-6-yl]-5-(1H-pyrazol-4-yl)phenol
CID 150471037
N-(9-azabicyclo[3.3.1]nonan-3-yl)-6-(2,8-dimethylimidazo[1,2-a]pyridin-6-yl)-N-methyl-[1,3]thiazolo[4,5-c]pyridin-2-amine
CID 151013143
2-methyl-5-[2-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-[1,3]thiazolo[5,4-b]pyridin-5-yl]indazole-7-carbonitrile
CID 151104199
5-[2-[9-azabicyclo[3.3.1]nonan-3-yl(methyl)amino]-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-methylindazole-7-carbonitrile
CID 150698880
6-(7-fluoro-2-methylindazol-5-yl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-b]pyrazin-2-amine
CID 150126397
N-methyl-6-(2-methylindazol-5-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-benzothiazol-2-amine
CID 152719069

Frequently Asked Questions

What is the IUPAC name of 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile?
The IUPAC name of 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile (CID 161236494) is 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile.
What is the SMILES notation for 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile?
The canonical SMILES for 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile is Cc1cn2cc(-c3cc4sc(OC5CC(C)(C)NC(C)(C)C5)nc4cn3)cc(C#N)c2n1.Cc1cn2cc(-c3cc4sc(OC5CC(C)(C)NC(C)(C)C5)nc4cn3)cc(F)c2n1.Cc1nn2cc(-c3cc4sc(N(C)C5CC(C)(C)NC(C)(C)C5)nc4cn3)nc2s1.
What is the InChIKey of 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile?
The InChIKey is UZKZFHCOJRMCBK-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H26N6OS.C23H26FN5OS.C21H27N7S2/c1-14-12-30-13-16(6-15(10-25)21(30)27-14)18-7-20-19(11-26-18)28-22(32-20)31-17-8-23(2,3)29-24(4,5)9-17;1-13-11-29-12-14(6-16(24)20(29)26-13)17-7-19-18(10-25-17)27-21(31-19)30-15-8-22(2,3)28-23(4,5)9-15;1-12-25-28-11-16(24-19(28)29-12)14-7-17-15(10-22-14)23-18(30-17)27(6)13-8-20(2,3)26-21(4,5)9-13/h6-7,11-13,17,29H,8-9H2,1-5H3;6-7,10-12,15,28H,8-9H2,1-5H3;7,10-11,13,26H,8-9H2,1-6H3.
What are the key properties of 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile?
6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile has a molecular weight of 1327.77 g/mol, XLogP of 14.53, 9 rotatable bonds, 3 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridine;N-methyl-6-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-[1,3]thiazolo[4,5-c]pyridin-2-amine;2-methyl-6-[2-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-[1,3]thiazolo[4,5-c]pyridin-6-yl]imidazo[1,2-a]pyridine-8-carbonitrile is sourced from PubChem (CID 161236494), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).