2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide

C₃₀₈H₄₃₆N₅₀O₃₇S₄ — CID 161383975

About 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide

2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide (PubChem CID 161383975) has the molecular formula C₃₀₈H₄₃₆N₅₀O₃₇S₄ and a molecular weight of 5559.46 g/mol. Its IUPAC name is 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide.

Molecular Properties

• Compound Name: 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide
• PubChem CID: 161383975
• Molecular Formula: C₃₀₈H₄₃₆N₅₀O₃₇S₄
• Molecular Weight: 5559.46 g/mol
• Exact Mass: 5555.27
• IUPAC Name: 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide
• SMILES: CCC(=O)CN1CC2(CCC(NC)(c3ccccc3)CC2)N(CC2(O)CCC2)C1=O.CCCN1C(=O)N(CC(=O)N2CCS(=O)(=O)CC2)CC12CCC(NC)(c1ccccc1)CC2.CCCN1C(=O)N(CC(=O)N2CCS(=O)(=O)CC2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCC(N)=O)C(=O)N2CC1(C#N)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccccn1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)N1CCOCC1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)N1CCOCC1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccccn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(N)=O)C(=O)N2CC1(C#N)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(CC(=O)N1CCS(=O)(=O)CC1)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(CC(N)=O)C(=O)N2CC1(O)CCC1.CSc1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1
• InChI: InChI=1S/C30H40N4O2S.C29H38N4O3.C28H37N5O2.C27H37N5O3.C27H40N4O4.C27H40N4O3.C25H38N4O4S.C24H33N5O2.C24H36N4O4S.C24H35N3O3.C22H32N4O3.C21H30N4O4S/c1-32(2)30(24-10-5-4-6-11-24)15-13-29(14-16-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-19-27(37-3)12-17-31-25;1-31(2)29(23-9-4-3-5-10-23)16-14-27(15-17-29)21-32(20-25(34)19-24-11-6-7-18-30-24)26(35)33(27)22-28(36)12-8-13-28;1-31(2)28(23-11-4-3-5-12-23)16-14-27(15-17-28)21-32(26(35)33(27)19-22-9-8-10-22)20-25(34)30-24-13-6-7-18-29-24;1-30(2)27(21-7-4-3-5-8-21)15-13-26(14-16-27)20-31(17-22(33)9-10-23(29)34)24(35)32(26)19-25(18-28)11-6-12-25;1-28(2)27(22-7-4-3-5-8-22)13-11-25(12-14-27)20-30(19-23(32)29-15-17-35-18-16-29)24(33)31(25)21-26(34)9-6-10-26;1-28(2)27(23-9-4-3-5-10-23)13-11-26(12-14-27)21-30(20-24(32)29-15-17-34-18-16-29)25(33)31(26)19-22-7-6-8-22;1-4-14-29-23(31)28(19-22(30)27-15-17-34(32,33)18-16-27)20-24(29)10-12-25(13-11-24,26(2)3)21-8-6-5-7-9-21;1-27(2)24(19-7-4-3-5-8-19)13-11-23(12-14-24)18-28(15-20(26)30)21(31)29(23)17-22(16-25)9-6-10-22;1-3-13-28-22(30)27(18-21(29)26-14-16-33(31,32)17-15-26)19-23(28)9-11-24(25-2,12-10-23)20-7-5-4-6-8-20;1-3-20(28)16-26-17-22(27(21(26)29)18-23(30)10-7-11-23)12-14-24(25-2,15-13-22)19-8-5-4-6-9-19;1-24-22(17-6-3-2-4-7-17)12-10-20(11-13-22)15-25(14-18(23)27)19(28)26(20)16-21(29)8-5-9-21;1-22-21(17-5-3-2-4-6-17)9-7-20(8-10-21)16-25(19(27)23-20)15-18(26)24-11-13-30(28,29)14-12-24/h4-6,10-12,17,19,23H,7-9,13-16,18,20-22H2,1-3H3;3-7,9-11,18,36H,8,12-17,19-22H2,1-2H3;3-7,11-13,18,22H,8-10,14-17,19-21H2,1-2H3,(H,29,30,34);3-5,7-8H,6,9-17,19-20H2,1-2H3,(H2,29,34);3-5,7-8,34H,6,9-21H2,1-2H3;3-5,9-10,22H,6-8,11-21H2,1-2H3;5-9H,4,10-20H2,1-3H3;3-5,7-8H,6,9-15,17-18H2,1-2H3,(H2,26,30);4-8,25H,3,9-19H2,1-2H3;4-6,8-9,25,30H,3,7,10-18H2,1-2H3;2-4,6-7,24,29H,5,8-16H2,1H3,(H2,23,27);2-6,22H,7-16H2,1H3,(H,23,27)
• InChIKey: VSBYMWJGYTYTNU-UHFFFAOYSA-N
• XLogP: 33.56
• TPSA: 981.68 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 55
• Rotatable Bonds: 80
• Heavy Atoms: 399
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	5559.46
LogP ≤ 5	33.56
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	55

Frequently Asked Questions

What is the IUPAC name of 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide?

The IUPAC name of 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide (CID 161383975) is 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide.

What is the SMILES notation for 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide?

The canonical SMILES for 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide is CCC(=O)CN1CC2(CCC(NC)(c3ccccc3)CC2)N(CC2(O)CCC2)C1=O.CCCN1C(=O)N(CC(=O)N2CCS(=O)(=O)CC2)CC12CCC(NC)(c1ccccc1)CC2.CCCN1C(=O)N(CC(=O)N2CCS(=O)(=O)CC2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCC(N)=O)C(=O)N2CC1(C#N)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccccn1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)N1CCOCC1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)N1CCOCC1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccccn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(N)=O)C(=O)N2CC1(C#N)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(CC(=O)N1CCS(=O)(=O)CC1)C(=O)N2.CNC1(c2ccccc2)CCC2(CC1)CN(CC(N)=O)C(=O)N2CC1(O)CCC1.CSc1ccnc(CC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1.

What is the InChIKey of 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide?

The InChIKey is VSBYMWJGYTYTNU-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H40N4O2S.C29H38N4O3.C28H37N5O2.C27H37N5O3.C27H40N4O4.C27H40N4O3.C25H38N4O4S.C24H33N5O2.C24H36N4O4S.C24H35N3O3.C22H32N4O3.C21H30N4O4S/c1-32(2)30(24-10-5-4-6-11-24)15-13-29(14-16-30)22-33(28(36)34(29)20-23-8-7-9-23)21-26(35)18-25-19-27(37-3)12-17-31-25;1-31(2)29(23-9-4-3-5-10-23)16-14-27(15-17-29)21-32(20-25(34)19-24-11-6-7-18-30-24)26(35)33(27)22-28(36)12-8-13-28;1-31(2)28(23-11-4-3-5-12-23)16-14-27(15-17-28)21-32(26(35)33(27)19-22-9-8-10-22)20-25(34)30-24-13-6-7-18-29-24;1-30(2)27(21-7-4-3-5-8-21)15-13-26(14-16-27)20-31(17-22(33)9-10-23(29)34)24(35)32(26)19-25(18-28)11-6-12-25;1-28(2)27(22-7-4-3-5-8-22)13-11-25(12-14-27)20-30(19-23(32)29-15-17-35-18-16-29)24(33)31(25)21-26(34)9-6-10-26;1-28(2)27(23-9-4-3-5-10-23)13-11-26(12-14-27)21-30(20-24(32)29-15-17-34-18-16-29)25(33)31(26)19-22-7-6-8-22;1-4-14-29-23(31)28(19-22(30)27-15-17-34(32,33)18-16-27)20-24(29)10-12-25(13-11-24,26(2)3)21-8-6-5-7-9-21;1-27(2)24(19-7-4-3-5-8-19)13-11-23(12-14-24)18-28(15-20(26)30)21(31)29(23)17-22(16-25)9-6-10-22;1-3-13-28-22(30)27(18-21(29)26-14-16-33(31,32)17-15-26)19-23(28)9-11-24(25-2,12-10-23)20-7-5-4-6-8-20;1-3-20(28)16-26-17-22(27(21(26)29)18-23(30)10-7-11-23)12-14-24(25-2,15-13-22)19-8-5-4-6-9-19;1-24-22(17-6-3-2-4-7-17)12-10-20(11-13-22)15-25(14-18(23)27)19(28)26(20)16-21(29)8-5-9-21;1-22-21(17-5-3-2-4-6-17)9-7-20(8-10-21)16-25(19(27)23-20)15-18(26)24-11-13-30(28,29)14-12-24/h4-6,10-12,17,19,23H,7-9,13-16,18,20-22H2,1-3H3;3-7,9-11,18,36H,8,12-17,19-22H2,1-2H3;3-7,11-13,18,22H,8-10,14-17,19-21H2,1-2H3,(H,29,30,34);3-5,7-8H,6,9-17,19-20H2,1-2H3,(H2,29,34);3-5,7-8,34H,6,9-21H2,1-2H3;3-5,9-10,22H,6-8,11-21H2,1-2H3;5-9H,4,10-20H2,1-3H3;3-5,7-8H,6,9-15,17-18H2,1-2H3,(H2,26,30);4-8,25H,3,9-19H2,1-2H3;4-6,8-9,25,30H,3,7,10-18H2,1-2H3;2-4,6-7,24,29H,5,8-16H2,1H3,(H2,23,27);2-6,22H,7-16H2,1H3,(H,23,27).

What are the key properties of 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide?

2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide has a molecular weight of 5559.46 g/mol, XLogP of 33.56, 80 rotatable bonds, 13 hydrogen bond donors, and 55 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;5-[1-[(1-cyanocyclobutyl)methyl]-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[3-(4-methylsulfanyl-2-pyridinyl)-2-oxopropyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyridin-2-ylacetamide;8-(dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-morpholin-4-yl-2-oxoethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-3-pyridin-2-ylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxoethyl]-8-(methylamino)-8-phenyl-1-propyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide is sourced from PubChem (CID 161383975), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 161383975 — identifiers, structure, computed properties (public domain)

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