2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide

C108H108ClF8N31O10 — CID 162038625

IUPAC2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCc1cc(-c2cc(F)c(Cl)cn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cccc3conc23)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccno2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccno2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12.Cc1cc(-c2cncc(OC(F)(F)F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2ncc(F)[nH]2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12
InChIInChI=1S/C21H21N5O2.C19H18F3N5O2.C18H17ClFN5O.C17H19FN6O.C17H19N5O2.C16H14F3N5O2/c1-12-9-16(15-6-4-5-13-10-28-25-17(13)15)23-19-18(22-11-26(12)19)20(27)24-21(2,3)14-7-8-14;1-10-5-15(13-6-14(8-23-7-13)29-19(20,21)22)26-17-16(24-9-27(10)17)18(28)25-11(2)12-3-4-12;1-9-5-15(14-6-13(20)12(19)7-21-14)24-17-16(22-8-25(9)17)18(26)23-10(2)11-3-4-11;1-9-6-11(14-19-7-12(18)22-14)21-15-13(20-8-24(9)15)16(25)23-17(2,3)10-4-5-10;1-10-8-12(13-6-7-19-24-13)20-15-14(18-9-22(10)15)16(23)21-17(2,3)11-4-5-11;1-8-6-10(11-4-5-21-26-11)22-14-12(20-7-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h4-6,9-11,14H,7-8H2,1-3H3,(H,24,27);5-9,11-12H,3-4H2,1-2H3,(H,25,28);5-8,10-11H,3-4H2,1-2H3,(H,23,26);6-8,10H,4-5H2,1-3H3,(H,19,22)(H,23,25);6-9,11H,4-5H2,1-3H3,(H,21,23);4-7,9,13H,2-3H2,1H3,(H,23,25)/t;11-;10-;;;/m.00.../s1
InChIKeyYWYZECIBZVVWME-KIBYXFQHSA-N
MW2187.70 g/mol
LogP18.57
Rot. Bonds25

About 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide

2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide (PubChem CID 162038625) has the molecular formula C108H108ClF8N31O10 and a molecular weight of 2187.70 g/mol. Its IUPAC name is 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide.

Molecular Properties

Compound Name2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
PubChem CID162038625
Molecular FormulaC108H108ClF8N31O10
Molecular Weight2187.70 g/mol
Exact Mass2185.85
IUPAC Name2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
SMILESCc1cc(-c2cc(F)c(Cl)cn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cccc3conc23)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccno2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccno2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12.Cc1cc(-c2cncc(OC(F)(F)F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2ncc(F)[nH]2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12
InChIInChI=1S/C21H21N5O2.C19H18F3N5O2.C18H17ClFN5O.C17H19FN6O.C17H19N5O2.C16H14F3N5O2/c1-12-9-16(15-6-4-5-13-10-28-25-17(13)15)23-19-18(22-11-26(12)19)20(27)24-21(2,3)14-7-8-14;1-10-5-15(13-6-14(8-23-7-13)29-19(20,21)22)26-17-16(24-9-27(10)17)18(28)25-11(2)12-3-4-12;1-9-5-15(14-6-13(20)12(19)7-21-14)24-17-16(22-8-25(9)17)18(26)23-10(2)11-3-4-11;1-9-6-11(14-19-7-12(18)22-14)21-15-13(20-8-24(9)15)16(25)23-17(2,3)10-4-5-10;1-10-8-12(13-6-7-19-24-13)20-15-14(18-9-22(10)15)16(23)21-17(2,3)11-4-5-11;1-8-6-10(11-4-5-21-26-11)22-14-12(20-7-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h4-6,9-11,14H,7-8H2,1-3H3,(H,24,27);5-9,11-12H,3-4H2,1-2H3,(H,25,28);5-8,10-11H,3-4H2,1-2H3,(H,23,26);6-8,10H,4-5H2,1-3H3,(H,19,22)(H,23,25);6-9,11H,4-5H2,1-3H3,(H,21,23);4-7,9,13H,2-3H2,1H3,(H,23,25)/t;11-;10-;;;/m.00.../s1
InChIKeyYWYZECIBZVVWME-KIBYXFQHSA-N
XLogP18.57
TPSA497.52 Ų
H-Bond Donors7
H-Bond Acceptors34
Rotatable Bonds25
Heavy Atoms158
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002187.70
LogP ≤ 518.57
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1034

Analyze 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide with MolForge

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Related Compounds

6-chloro-2-propan-2-ylimidazo[1,2-b]pyridazine;6-cyclopropyl-2-propan-2-ylimidazo[1,2-b]pyridazine;6-fluoro-2-propan-2-ylimidazo[1,2-b]pyridazine;6-imidazol-1-yl-2-propan-2-ylimidazo[1,2-b]pyridazine;6-methoxy-2-propan-2-ylimidazo[1,2-b]pyridazine;6-methyl-2-propan-2-ylimidazo[1,2-b]pyridazine;2-propan-2-yl-3a,7a-dihydro-1H-pyrrolo[2,3-c]pyridine;2-propan-2-yl-3a,7a-dihydro-1H-pyrrolo[3,2-c]pyridine;3-propan-2-yl-2,1-benzoxazole;bis(2-propan-2-ylimidazo[1,2-b]pyridazine);4-(2-propan-2-ylimidazo[1,2-b]pyridazin-6-yl)morpholine;2-propan-2-yl-6-pyrrolidin-1-ylimidazo[1,2-b]pyridazine;2-propan-2-yl-6-(trifluoromethyl)imidazo[1,2-b]pyridazine
CID 157458205
4-chloro-7-[(2S)-1-methylpyrrolidin-2-yl]-3H-imidazo[4,5-c]pyridine;1-methoxy-4-[(2S)-1-methylpyrrolidin-2-yl]-[1]benzofuro[2,3-c]pyridine;4-methoxy-7-[(2S)-1-methylpyrrolidin-2-yl]furo[3,2-c]pyridine;4-methoxy-7-[(2S)-1-methylpyrrolidin-2-yl]-[1,3]oxazolo[4,5-c]pyridine;5-[(2S)-1-methylpyrrolidin-2-yl]-1H-pyrrolo[2,3-b]pyridine;3-[(2S)-1-methylpyrrolidin-2-yl]-4-(trifluoromethyl)-[1]benzofuro[2,3-b]pyridine;5-[(2S)-1-methylpyrrolidin-2-yl]-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
CID 157501418
(1R,5S)-N-[2-(1,2-benzoxazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(1-benzylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(1-chloroisoquinolin-4-yl)oxy-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-[(2-methyl-3-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-[4-(trifluoromethyl)pyridazin-3-yl]oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-1-[[3-(trifluoromethyl)-2-pyridinyl]oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 157987542
2-(4-chloro-5-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(cyclopropylamino)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1-methylpyrazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-3-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,3-oxazol-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-4-methyl-N-[(2S)-3-methylbutan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 158191746
2-(2,1-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(6-cyclopropyloxy-2-pyridinyl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-ethyl-2-(2-oxo-3-propan-2-ylimidazolidin-1-yl)imidazo[1,5-a]pyrimidine-8-carboxamide
CID 159337387
N-[(1S)-1-cyclopropylethyl]-2-(3-fluoro-2-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-2-(3-fluoro-2-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-[3-(1,3-oxazol-2-yl)phenyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(3-pyrimidin-2-ylphenyl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-fluoro-5-methoxyphenyl)-4-methyl-N-(1,1,1-trifluoropropan-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-fluoro-5-methoxyphenyl)-4-methyl-N-[(2R)-1,1,1-trifluoropropan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-fluoro-5-methoxyphenyl)-4-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]imidazo[1,5-a]pyrimidine-8-carboxamide
CID 160060668
4-chloro-7-[(2S)-1-methylpyrrolidin-2-yl]-3H-imidazo[4,5-c]pyridine;1-methoxy-4-[(2S)-1-methylpyrrolidin-2-yl]-[1]benzofuro[2,3-c]pyridine;4-methoxy-7-[(2S)-1-methylpyrrolidin-2-yl]-2,3-dihydrofuro[3,2-c]pyridine;4-methoxy-7-[(2S)-1-methylpyrrolidin-2-yl]furo[3,2-c]pyridine;4-methoxy-7-[(2S)-1-methylpyrrolidin-2-yl]-[1,3]oxazolo[4,5-c]pyridine;5-[(2S)-1-methylpyrrolidin-2-yl]-2,3-dihydrofuro[2,3-b]pyridine;5-[(2S)-1-methylpyrrolidin-2-yl]furo[2,3-b]pyridine;5-[(2S)-1-methylpyrrolidin-2-yl]-1H-pyrrolo[2,3-b]pyridine;5-[(2S)-1-methylpyrrolidin-2-yl]-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
CID 160559277
6-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-2-[1-(2-methylpropyl)indol-5-yl]pyrimidine-4-carboxamide;1-[6-(3-methoxy-1H-indol-5-yl)-2-pyridinyl]-2-[4-(trifluoromethyl)phenyl]ethanone;2-[1-(4-methylphenyl)benzimidazol-5-yl]-6-[(2-oxopyrrolidin-3-yl)amino]pyrimidine-4-carboxamide;2-[3-(4-methylphenyl)benzimidazol-5-yl]-6-[(2-oxopyrrolidin-3-yl)amino]pyrimidine-4-carboxamide;6-[1-(2-methylpropyl)indol-5-yl]pyridine-2-carbaldehyde
CID 160728328
2-(1,2-benzoxazol-6-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(1,2-benzoxazol-7-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(2,1-benzoxazol-6-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-fluoro-5-methoxyphenyl)-N-[(1S,5R)-8-methoxy-3-bicyclo[3.2.1]octanyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(3-fluorophenyl)-4-methyl-N-(1,1,1-trifluorobut-3-yn-2-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S,5R)-8-methoxy-3-bicyclo[3.2.1]octanyl]-2-(3-methoxyphenyl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide
CID 161269754
CID 163709343
CID 163709343
5-(1,3-benzoxazol-5-yl)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(6-chloro-2-pyridinyl)-N-(2-cyclopropylpropan-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(3,3-difluoropiperidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(2-fluoro-3-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-5-(6-fluoro-3-pyridinyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-pyridin-3-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163817943
4-(8-amino-1-furo[3,2-b]pyridin-2-ylimidazo[1,5-a]pyrazin-3-yl)-N,N-dimethylpiperidine-1-carboxamide;2-[8-amino-3-[4-(2-pyridin-3-ylacetyl)cyclohexyl]imidazo[1,5-a]pyrazin-1-yl]-1,5-dihydroindol-4-one;1-[4-[8-amino-1-(7-pyridin-2-yl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]propan-1-one
CID 123159336

Frequently Asked Questions

What is the IUPAC name of 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?
The IUPAC name of 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide (CID 162038625) is 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide.
What is the SMILES notation for 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?
The canonical SMILES for 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide is Cc1cc(-c2cc(F)c(Cl)cn2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2cccc3conc23)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccno2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.Cc1cc(-c2ccno2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)ncn12.Cc1cc(-c2cncc(OC(F)(F)F)c2)nc2c(C(=O)N[C@@H](C)C3CC3)ncn12.Cc1cc(-c2ncc(F)[nH]2)nc2c(C(=O)NC(C)(C)C3CC3)ncn12.
What is the InChIKey of 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?
The InChIKey is YWYZECIBZVVWME-KIBYXFQHSA-N. The full InChI is InChI=1S/C21H21N5O2.C19H18F3N5O2.C18H17ClFN5O.C17H19FN6O.C17H19N5O2.C16H14F3N5O2/c1-12-9-16(15-6-4-5-13-10-28-25-17(13)15)23-19-18(22-11-26(12)19)20(27)24-21(2,3)14-7-8-14;1-10-5-15(13-6-14(8-23-7-13)29-19(20,21)22)26-17-16(24-9-27(10)17)18(28)25-11(2)12-3-4-12;1-9-5-15(14-6-13(20)12(19)7-21-14)24-17-16(22-8-25(9)17)18(26)23-10(2)11-3-4-11;1-9-6-11(14-19-7-12(18)22-14)21-15-13(20-8-24(9)15)16(25)23-17(2,3)10-4-5-10;1-10-8-12(13-6-7-19-24-13)20-15-14(18-9-22(10)15)16(23)21-17(2,3)11-4-5-11;1-8-6-10(11-4-5-21-26-11)22-14-12(20-7-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h4-6,9-11,14H,7-8H2,1-3H3,(H,24,27);5-9,11-12H,3-4H2,1-2H3,(H,25,28);5-8,10-11H,3-4H2,1-2H3,(H,23,26);6-8,10H,4-5H2,1-3H3,(H,19,22)(H,23,25);6-9,11H,4-5H2,1-3H3,(H,21,23);4-7,9,13H,2-3H2,1H3,(H,23,25)/t;11-;10-;;;/m.00.../s1.
What are the key properties of 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide?
2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide has a molecular weight of 2187.70 g/mol, XLogP of 18.57, 25 rotatable bonds, 7 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2,1-benzoxazol-7-yl)-N-(2-cyclopropylpropan-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;2-(5-chloro-4-fluoro-2-pyridinyl)-N-[(1S)-1-cyclopropylethyl]-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-[(1S)-1-cyclopropylethyl]-4-methyl-2-[5-(trifluoromethoxy)-3-pyridinyl]imidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-2-(5-fluoro-1H-imidazol-2-yl)-4-methylimidazo[1,5-a]pyrimidine-8-carboxamide;N-(2-cyclopropylpropan-2-yl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-methyl-2-(1,2-oxazol-5-yl)imidazo[1,5-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 162038625), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).