2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C72H85F3N30O7 — CID 162133841

IUPAC2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCC(C)Oc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCN(C)CC3)nc12.CNC1CCN(c2ccn3nc(N)c(C(=O)Nc4cnccc4OC)c3n2)C1.COc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCC(N(C)C)CC3)nc12.Cc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12
InChIInChI=1S/2C20H26N8O2.C18H22N8O2.C14H11F3N6O/c1-26(2)13-5-9-27(10-6-13)16-7-11-28-19(24-16)17(18(21)25-28)20(29)23-14-12-22-8-4-15(14)30-3;1-13(2)30-15-4-6-22-12-14(15)23-20(29)17-18(21)25-28-7-5-16(24-19(17)28)27-10-8-26(3)9-11-27;1-20-11-4-7-25(10-11)14-5-8-26-17(23-14)15(16(19)24-26)18(27)22-12-9-21-6-3-13(12)28-2;1-7-2-4-19-6-8(7)20-13(24)10-11(18)22-23-5-3-9(14(15,16)17)21-12(10)23/h4,7-8,11-13H,5-6,9-10H2,1-3H3,(H2,21,25)(H,23,29);4-7,12-13H,8-11H2,1-3H3,(H2,21,25)(H,23,29);3,5-6,8-9,11,20H,4,7,10H2,1-2H3,(H2,19,24)(H,22,27);2-6H,1H3,(H2,18,22)(H,20,24)
InChIKeyZIZVTPMHWQKRMQ-UHFFFAOYSA-N
MW1539.67 g/mol
LogP6.05
Rot. Bonds17

About 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 162133841) has the molecular formula C72H85F3N30O7 and a molecular weight of 1539.67 g/mol. Its IUPAC name is 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID162133841
Molecular FormulaC72H85F3N30O7
Molecular Weight1539.67 g/mol
Exact Mass1538.72
IUPAC Name2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCC(C)Oc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCN(C)CC3)nc12.CNC1CCN(c2ccn3nc(N)c(C(=O)Nc4cnccc4OC)c3n2)C1.COc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCC(N(C)C)CC3)nc12.Cc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12
InChIInChI=1S/2C20H26N8O2.C18H22N8O2.C14H11F3N6O/c1-26(2)13-5-9-27(10-6-13)16-7-11-28-19(24-16)17(18(21)25-28)20(29)23-14-12-22-8-4-15(14)30-3;1-13(2)30-15-4-6-22-12-14(15)23-20(29)17-18(21)25-28-7-5-16(24-19(17)28)27-10-8-26(3)9-11-27;1-20-11-4-7-25(10-11)14-5-8-26-17(23-14)15(16(19)24-26)18(27)22-12-9-21-6-3-13(12)28-2;1-7-2-4-19-6-8(7)20-13(24)10-11(18)22-23-5-3-9(14(15,16)17)21-12(10)23/h4,7-8,11-13H,5-6,9-10H2,1-3H3,(H2,21,25)(H,23,29);4-7,12-13H,8-11H2,1-3H3,(H2,21,25)(H,23,29);3,5-6,8-9,11,20H,4,7,10H2,1-2H3,(H2,19,24)(H,22,27);2-6H,1H3,(H2,18,22)(H,20,24)
InChIKeyZIZVTPMHWQKRMQ-UHFFFAOYSA-N
XLogP6.05
TPSA448.72 Ų
H-Bond Donors9
H-Bond Acceptors33
Rotatable Bonds17
Heavy Atoms112
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001539.67
LogP ≤ 56.05
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1033

Analyze 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

2-amino-N-[4-[[(6S)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76285599
2-amino-6-fluoro-N-[4-[(3S)-piperidin-3-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76286963
2-amino-6-fluoro-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287697
2-amino-N-[4-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287701
2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287702
2-amino-N-[4-[[(3S)-1-azabicyclo[2.2.2]octan-3-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287848
2-amino-6-fluoro-N-[4-[1-(oxetan-3-yl)piperidin-4-yl]oxy-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287849
2-amino-6-fluoro-N-[4-(1-methylpiperidin-4-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287850
5-amino-N-[4-(2,2,2-trifluoroethoxy)pyridin-3-yl]-2,6,7,11-tetrazatricyclo[7.4.0.03,7]trideca-1,3,5,8-tetraene-4-carboxamide
CID 86299349
5-amino-11-methyl-N-[4-(2,2,2-trifluoroethoxy)pyridin-3-yl]-2,6,7,11-tetrazatricyclo[7.4.0.03,7]trideca-1,3,5,8-tetraene-4-carboxamide
CID 90409024
2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)-3-pyridinyl]-6-(cyanomethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76285746
2-amino-6-(cyanomethyl)-N-[4-(1-methylpiperidin-4-yl)oxy-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76285747

Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 162133841) is 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is CC(C)Oc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCN(C)CC3)nc12.CNC1CCN(c2ccn3nc(N)c(C(=O)Nc4cnccc4OC)c3n2)C1.COc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCC(N(C)C)CC3)nc12.Cc1ccncc1NC(=O)c1c(N)nn2ccc(C(F)(F)F)nc12.
What is the InChIKey of 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is ZIZVTPMHWQKRMQ-UHFFFAOYSA-N. The full InChI is InChI=1S/2C20H26N8O2.C18H22N8O2.C14H11F3N6O/c1-26(2)13-5-9-27(10-6-13)16-7-11-28-19(24-16)17(18(21)25-28)20(29)23-14-12-22-8-4-15(14)30-3;1-13(2)30-15-4-6-22-12-14(15)23-20(29)17-18(21)25-28-7-5-16(24-19(17)28)27-10-8-26(3)9-11-27;1-20-11-4-7-25(10-11)14-5-8-26-17(23-14)15(16(19)24-26)18(27)22-12-9-21-6-3-13(12)28-2;1-7-2-4-19-6-8(7)20-13(24)10-11(18)22-23-5-3-9(14(15,16)17)21-12(10)23/h4,7-8,11-13H,5-6,9-10H2,1-3H3,(H2,21,25)(H,23,29);4-7,12-13H,8-11H2,1-3H3,(H2,21,25)(H,23,29);3,5-6,8-9,11,20H,4,7,10H2,1-2H3,(H2,19,24)(H,22,27);2-6H,1H3,(H2,18,22)(H,20,24).
What are the key properties of 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 1539.67 g/mol, XLogP of 6.05, 17 rotatable bonds, 9 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[4-(dimethylamino)piperidin-1-yl]-N-(4-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(methylamino)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-(4-methylpiperazin-1-yl)-N-(4-propan-2-yloxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methyl-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 162133841), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).