(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide

C118H120Cl5F3N40O4 — CID 162230254

About (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide

(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide (PubChem CID 162230254) has the molecular formula C118H120Cl5F3N40O4 and a molecular weight of 2396.79 g/mol. Its IUPAC name is (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide.

Molecular Properties

• Compound Name: (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide
• PubChem CID: 162230254
• Molecular Formula: C118H120Cl5F3N40O4
• Molecular Weight: 2396.79 g/mol
• Exact Mass: 2392.88
• IUPAC Name: (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide
• SMILES: CC(=O)NC1CCCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C1.Cc1[nH]ncc1[C@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@H](C)O1.Cc1cnc(N2C[C@@H](C)C[C@@H](c3cn[nH]c3)C2)nc1-c1cnc2ccc(Cl)cn12.Cc1cnc(N2C[C@@H](C)O[C@H](c3cn[nH]c3)C2)nc1-c1cnc2ccc(Cl)cn12.Cc1cnc(N2C[C@H](C)C[C@H](c3cn[nH]c3)C2)nc1-c1cnc2ccc(Cl)cn12.NC(=O)[C@H]1CCCN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C1
• InChI: InChI=1S/2C21H22ClN7.2C20H20ClN7O.C19H19F3N6O.C17H17ClN6O/c2*1-13-5-15(16-7-25-26-8-16)11-28(10-13)21-24-6-14(2)20(27-21)18-9-23-19-4-3-17(22)12-29(18)19;1-12-5-23-20(27-9-13(2)29-17(11-27)14-6-24-25-7-14)26-19(12)16-8-22-18-4-3-15(21)10-28(16)18;1-12-9-27(11-18(29-12)15-7-24-26-13(15)2)20-22-6-5-16(25-20)17-8-23-19-4-3-14(21)10-28(17)19;1-12(29)25-14-3-2-8-27(11-14)17-6-7-23-18(26-17)15-9-24-16-5-4-13(10-28(15)16)19(20,21)22;18-12-3-4-15-21-8-14(24(15)10-12)13-5-6-20-17(22-13)23-7-1-2-11(9-23)16(19)25/h2*3-4,6-9,12-13,15H,5,10-11H2,1-2H3,(H,25,26);3-8,10,13,17H,9,11H2,1-2H3,(H,24,25);3-8,10,12,18H,9,11H2,1-2H3,(H,24,26);4-7,9-10,14H,2-3,8,11H2,1H3,(H,25,29);3-6,8,10-11H,1-2,7,9H2,(H2,19,25)/t2*13-,15+;13-,17+;12-,18+;;11-/m1010.0/s1
• InChIKey: ZVIABYJKWGPOBZ-LFNYBLILSA-N
• XLogP: 20.16
• TPSA: 483.29 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 38
• Rotatable Bonds: 18
• Heavy Atoms: 170
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2396.79
LogP ≤ 5	20.16
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	38

Frequently Asked Questions

What is the IUPAC name of (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide?

The IUPAC name of (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide (CID 162230254) is (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide.

What is the SMILES notation for (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide?

The canonical SMILES for (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide is CC(=O)NC1CCCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C1.Cc1[nH]ncc1[C@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@H](C)O1.Cc1cnc(N2C[C@@H](C)C[C@@H](c3cn[nH]c3)C2)nc1-c1cnc2ccc(Cl)cn12.Cc1cnc(N2C[C@@H](C)O[C@H](c3cn[nH]c3)C2)nc1-c1cnc2ccc(Cl)cn12.Cc1cnc(N2C[C@H](C)C[C@H](c3cn[nH]c3)C2)nc1-c1cnc2ccc(Cl)cn12.NC(=O)[C@H]1CCCN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C1.

What is the InChIKey of (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide?

The InChIKey is ZVIABYJKWGPOBZ-LFNYBLILSA-N. The full InChI is InChI=1S/2C21H22ClN7.2C20H20ClN7O.C19H19F3N6O.C17H17ClN6O/c2*1-13-5-15(16-7-25-26-8-16)11-28(10-13)21-24-6-14(2)20(27-21)18-9-23-19-4-3-17(22)12-29(18)19;1-12-5-23-20(27-9-13(2)29-17(11-27)14-6-24-25-7-14)26-19(12)16-8-22-18-4-3-15(21)10-28(16)18;1-12-9-27(11-18(29-12)15-7-24-26-13(15)2)20-22-6-5-16(25-20)17-8-23-19-4-3-14(21)10-28(17)19;1-12(29)25-14-3-2-8-27(11-14)17-6-7-23-18(26-17)15-9-24-16-5-4-13(10-28(15)16)19(20,21)22;18-12-3-4-15-21-8-14(24(15)10-12)13-5-6-20-17(22-13)23-7-1-2-11(9-23)16(19)25/h2*3-4,6-9,12-13,15H,5,10-11H2,1-2H3,(H,25,26);3-8,10,13,17H,9,11H2,1-2H3,(H,24,25);3-8,10,12,18H,9,11H2,1-2H3,(H,24,26);4-7,9-10,14H,2-3,8,11H2,1H3,(H,25,29);3-6,8,10-11H,1-2,7,9H2,(H2,19,25)/t2*13-,15+;13-,17+;12-,18+;;11-/m1010.0/s1.

What are the key properties of (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide?

(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide has a molecular weight of 2396.79 g/mol, XLogP of 20.16, 18 rotatable bonds, 6 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(1H-pyrazol-4-yl)morpholine;(2S,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(3S)-1-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]piperidine-3-carboxamide;6-chloro-3-[5-methyl-2-[(3S,5S)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;6-chloro-3-[5-methyl-2-[(3R,5R)-3-methyl-5-(1H-pyrazol-4-yl)piperidin-1-yl]pyrimidin-4-yl]imidazo[1,2-a]pyridine;N-[1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidin-3-yl]acetamide is sourced from PubChem (CID 162230254), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).