N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide

C19H16F4N4O — CID 162445062

IUPACN-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide
SMILESO=C(Nc1c[nH]c2cc(F)c(F)cc12)c1ccc(N2CCC(F)(F)CC2)nc1
InChIInChI=1S/C19H16F4N4O/c20-13-7-12-15(8-14(13)21)24-10-16(12)26-18(28)11-1-2-17(25-9-11)27-5-3-19(22,23)4-6-27/h1-2,7-10,24H,3-6H2,(H,26,28)
InChIKeyPXQRIMJOXCCUOL-UHFFFAOYSA-N
MW392.36 g/mol
LogP4.33
Rot. Bonds3

About N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide

N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide (PubChem CID 162445062) has the molecular formula C19H16F4N4O and a molecular weight of 392.36 g/mol. Its IUPAC name is N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide.

Molecular Properties

Compound NameN-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide
PubChem CID162445062
Molecular FormulaC19H16F4N4O
Molecular Weight392.36 g/mol
Exact Mass392.13
IUPAC NameN-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide
SMILESO=C(Nc1c[nH]c2cc(F)c(F)cc12)c1ccc(N2CCC(F)(F)CC2)nc1
InChIInChI=1S/C19H16F4N4O/c20-13-7-12-15(8-14(13)21)24-10-16(12)26-18(28)11-1-2-17(25-9-11)27-5-3-19(22,23)4-6-27/h1-2,7-10,24H,3-6H2,(H,26,28)
InChIKeyPXQRIMJOXCCUOL-UHFFFAOYSA-N
XLogP4.33
TPSA61.02 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds3
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500392.36
LogP ≤ 54.33
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

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Related Compounds

N-(5,6-difluoro-1H-indol-3-yl)-6-(trifluoromethyl)pyridine-3-carboxamide
CID 154652690
N-(5,6-difluoro-1H-indol-3-yl)-4-[6-(4,4-difluoropiperidin-1-yl)-5-fluoro-3-pyridinyl]-1,3-thiazole-2-carboxamide
CID 162444582
6-butoxy-N-(5,6-difluoro-1H-indol-3-yl)pyridine-3-carboxamide
CID 170068393
1-(5,6-difluoro-1H-indol-3-yl)-3-[6-(4,4-difluoropiperidin-1-yl)-5-(2-hydroxyethyl)-3-pyridinyl]urea
CID 156574923
N-(5,6-difluoro-1H-indol-3-yl)-5-[4-(trifluoromethoxy)piperidin-1-yl]pyrazine-2-carboxamide
CID 162445071
6-(3,3-difluoropyrrolidin-1-yl)-N-(4-fluoro-2-methylsulfonylphenyl)pyridine-3-carboxamide
CID 172605516
6-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-N-(2,3,4-trifluorophenyl)pyridine-3-carboxamide
CID 109160028
N-(5,6-difluoro-1H-indol-3-yl)-2-(1-hydroxypropyl)pyridine-4-carboxamide
CID 162445208
6-(3,3-difluoropyrrolidin-1-yl)-N-(3,4-dimethylphenyl)pyridine-3-carboxamide
CID 143994451
4-cyclohexyloxy-N-(5,6-difluoro-1H-indol-3-yl)benzamide
CID 162444906
N-(5,6-difluoro-1H-indol-3-yl)-5-fluoro-6-[6-(2,2,2-trifluoroethoxy)-2-azaspiro[3.3]heptan-2-yl]pyridine-3-carboxamide
CID 162444921
N-(5,6-difluoro-1H-indol-3-yl)-5-[6-(4,4-difluoro-1-methylcyclohexyl)-5-fluoro-3-pyridinyl]-1,2-oxazole-3-carboxamide
CID 162444435

Frequently Asked Questions

What is the IUPAC name of N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide?
The IUPAC name of N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide (CID 162445062) is N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide.
What is the SMILES notation for N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide?
The canonical SMILES for N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide is O=C(Nc1c[nH]c2cc(F)c(F)cc12)c1ccc(N2CCC(F)(F)CC2)nc1.
What is the InChIKey of N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide?
The InChIKey is PXQRIMJOXCCUOL-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H16F4N4O/c20-13-7-12-15(8-14(13)21)24-10-16(12)26-18(28)11-1-2-17(25-9-11)27-5-3-19(22,23)4-6-27/h1-2,7-10,24H,3-6H2,(H,26,28).
What are the key properties of N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide?
N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide has a molecular weight of 392.36 g/mol, XLogP of 4.33, 3 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for N-(5,6-difluoro-1H-indol-3-yl)-6-(4,4-difluoropiperidin-1-yl)pyridine-3-carboxamide is sourced from PubChem (CID 162445062), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).