1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide

C11H13F3N4O — CID 163263574

IUPAC1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
SMILESNC(=O)C1CCCCN1c1cncc(C(F)(F)F)n1
InChIInChI=1S/C11H13F3N4O/c12-11(13,14)8-5-16-6-9(17-8)18-4-2-1-3-7(18)10(15)19/h5-7H,1-4H2,(H2,15,19)
InChIKeyNWGWRUNIRFESDA-UHFFFAOYSA-N
MW274.25 g/mol
LogP1.34
Rot. Bonds2

About 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide

1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide (PubChem CID 163263574) has the molecular formula C11H13F3N4O and a molecular weight of 274.25 g/mol. Its IUPAC name is 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide.

Molecular Properties

Compound Name1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
PubChem CID163263574
Molecular FormulaC11H13F3N4O
Molecular Weight274.25 g/mol
Exact Mass274.10
IUPAC Name1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
SMILESNC(=O)C1CCCCN1c1cncc(C(F)(F)F)n1
InChIInChI=1S/C11H13F3N4O/c12-11(13,14)8-5-16-6-9(17-8)18-4-2-1-3-7(18)10(15)19/h5-7H,1-4H2,(H2,15,19)
InChIKeyNWGWRUNIRFESDA-UHFFFAOYSA-N
XLogP1.34
TPSA72.11 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds2
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500274.25
LogP ≤ 51.34
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

(3S)-3-[(3,6-dimethylpyrazin-2-yl)amino]azepan-2-one
CID 40506874
1-[5-(Trifluoromethyl)pyrazin-2-yl]piperidin-3-one
CID 71226134
(2S,3R)-2-methyl-3-[[5-(trifluoromethyl)pyrazin-2-yl]amino]piperidine-1-carbaldehyde
CID 90405043
(2S,4R)-4-fluoro-N-[6-(trifluoromethyl)pyrazin-2-yl]pyrrolidine-2-carboxamide;hydrochloride
CID 126643496
(2S,4R)-4-fluoro-N-[6-(trifluoromethyl)pyrazin-2-yl]pyrrolidine-2-carboxamide
CID 126643497
(2S,4R)-N-chloro-4-fluoro-N-[6-(trifluoromethyl)pyrazin-2-yl]pyrrolidine-2-carboxamide
CID 140318889
5-(4,4-Difluoropiperidin-1-yl)-6-methylpyrazin-2-amine
CID 156574343
(1R,3S,5R)-N-[6-(trifluoromethyl)pyrazin-2-yl]-2-azabicyclo[3.1.0]hexane-3-carboxamide
CID 166517793
N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
CID 167035122
1-methyl-N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
CID 167035338
N-[6-(trifluoromethyl)pyrazin-2-yl]-2-azabicyclo[3.1.0]hexane-3-carboxamide
CID 168753845
(1R,3S)-N-[6-(trifluoromethyl)pyrazin-2-yl]-2-azabicyclo[3.1.0]hexane-3-carboxamide
CID 169855218

Frequently Asked Questions

What is the IUPAC name of 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
The IUPAC name of 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide (CID 163263574) is 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide.
What is the SMILES notation for 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
The canonical SMILES for 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide is NC(=O)C1CCCCN1c1cncc(C(F)(F)F)n1.
What is the InChIKey of 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
The InChIKey is NWGWRUNIRFESDA-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H13F3N4O/c12-11(13,14)8-5-16-6-9(17-8)18-4-2-1-3-7(18)10(15)19/h5-7H,1-4H2,(H2,15,19).
What are the key properties of 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide has a molecular weight of 274.25 g/mol, XLogP of 1.34, 2 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide is sourced from PubChem (CID 163263574), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).