N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide

C163H134BrF10N35O10 — CID 163929718

IUPACN-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
SMILESC=C(C)c1cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1C#N.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(Br)c(CNC)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.Cn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C5CC5)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.N#Cc1c(C2CC2)cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n1-c1ccc(F)cc1
InChIInChI=1S/2C36H31F2N7O2.C31H23F2N7O2.C30H26BrF2N7O2.C30H23F2N7O2/c37-24-8-11-27(12-9-24)45-33(17-39)29(21-6-7-21)16-31(36(45)47)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-4-2-1-3-5-26;1-21(2)29-16-31(36(47)45(33(29)17-39)27-11-8-24(37)9-12-27)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-6-4-3-5-7-26;1-39-16-19(15-37-39)18-10-25(29(35)36-14-18)23-9-6-21(11-27(23)33)38-30(41)26-12-24(17-2-3-17)28(13-34)40(31(26)42)22-7-4-20(32)5-8-22;1-3-39-16-18(14-37-39)17-10-23(28(34)36-13-17)22-9-6-20(11-26(22)33)38-29(41)24-12-25(31)27(15-35-2)40(30(24)42)21-7-4-19(32)5-8-21;1-3-38-16-19(15-36-38)18-11-24(28(34)35-14-18)23-9-6-21(12-26(23)32)37-29(40)25-10-17(2)27(13-33)39(30(25)41)22-7-4-20(31)5-8-22/h8-16,18-21,26H,1-7H2,(H2,40,41)(H,43,46);8-16,18-20,26H,1,3-7H2,2H3,(H2,40,41)(H,43,46);4-12,14-17H,2-3H2,1H3,(H2,35,36)(H,38,41);4-14,16,35H,3,15H2,1-2H3,(H2,34,36)(H,38,41);4-12,14-16H,3H2,1-2H3,(H2,34,35)(H,37,40)
InChIKeyRHRACLVIPKURHC-UHFFFAOYSA-N
MW3012.98 g/mol
LogP30.03
Rot. Bonds34

About N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide

N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide (PubChem CID 163929718) has the molecular formula C163H134BrF10N35O10 and a molecular weight of 3012.98 g/mol. Its IUPAC name is N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide.

Molecular Properties

Compound NameN-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
PubChem CID163929718
Molecular FormulaC163H134BrF10N35O10
Molecular Weight3012.98 g/mol
Exact Mass3010.01
IUPAC NameN-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
SMILESC=C(C)c1cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1C#N.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(Br)c(CNC)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.Cn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C5CC5)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.N#Cc1c(C2CC2)cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n1-c1ccc(F)cc1
InChIInChI=1S/2C36H31F2N7O2.C31H23F2N7O2.C30H26BrF2N7O2.C30H23F2N7O2/c37-24-8-11-27(12-9-24)45-33(17-39)29(21-6-7-21)16-31(36(45)47)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-4-2-1-3-5-26;1-21(2)29-16-31(36(47)45(33(29)17-39)27-11-8-24(37)9-12-27)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-6-4-3-5-7-26;1-39-16-19(15-37-39)18-10-25(29(35)36-14-18)23-9-6-21(11-27(23)33)38-30(41)26-12-24(17-2-3-17)28(13-34)40(31(26)42)22-7-4-20(32)5-8-22;1-3-39-16-18(14-37-39)17-10-23(28(34)36-13-17)22-9-6-20(11-26(22)33)38-29(41)24-12-25(31)27(15-35-2)40(30(24)42)21-7-4-19(32)5-8-21;1-3-38-16-19(15-36-38)18-11-24(28(34)35-14-18)23-9-6-21(12-26(23)32)37-29(40)25-10-17(2)27(13-33)39(30(25)41)22-7-4-20(31)5-8-22/h8-16,18-21,26H,1-7H2,(H2,40,41)(H,43,46);8-16,18-20,26H,1,3-7H2,2H3,(H2,40,41)(H,43,46);4-12,14-17H,2-3H2,1H3,(H2,35,36)(H,38,41);4-14,16,35H,3,15H2,1-2H3,(H2,34,36)(H,38,41);4-12,14-16H,3H2,1-2H3,(H2,34,35)(H,37,40)
InChIKeyRHRACLVIPKURHC-UHFFFAOYSA-N
XLogP30.03
TPSA646.34 Ų
H-Bond Donors11
H-Bond Acceptors40
Rotatable Bonds34
Heavy Atoms219
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003012.98
LogP ≤ 530.03
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1040

Analyze N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide with MolForge

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Related Compounds

(2R)-2-[[(2S)-2-(2-fluoro-4-methylphenyl)propyl]amino]-N-[5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-phenylacetamide;(2S)-2-[[(2S)-2-(3-fluoro-4-methylphenyl)propyl]amino]-N-[5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-phenylacetamide;(2S)-2-[[(2R)-2-(3-fluoro-4-methylphenyl)propyl]amino]-N-[5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-phenylacetamide;(2R)-2-[[(2R)-2-(3-fluoro-4-methylphenyl)propyl]amino]-N-[5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-phenylacetamide;(2S)-2-[[(2R)-2-(4-methylphenyl)propyl]amino]-N-[5-[(3R)-3-methylpyrrolidin-1-yl]-2-pyridinyl]-2-phenylacetamide;2-[[(2S)-2-(4-methylphenyl)propyl]amino]-N-[5-[(3R)-3-methylpyrrolidin-1-yl]-2-pyridinyl]-2-phenylacetamide
CID 158380027
1-[1-(cyclopropylmethyl)-3-[4-(2-fluorophenyl)anilino]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone;1-[1-(cyclopropylmethyl)-3-[4-(3-fluorophenyl)anilino]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone;1-[1-(cyclopropylmethyl)-3-[4-(2-methylpyrazol-3-yl)anilino]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone;1-[1-(cyclopropylmethyl)-3-(4-pyridin-4-ylanilino)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
CID 158436810
1-[1-(cyclopropylmethyl)-3-[4-(2-fluorophenyl)anilino]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone;1-[1-(cyclopropylmethyl)-3-[4-(3-fluorophenyl)anilino]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone;1-[1-(cyclopropylmethyl)-3-(4-methylanilino)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone;1-[1-(cyclopropylmethyl)-3-(4-pyridin-4-ylanilino)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone;1-methylpyrazole
CID 158979848
CID 159443131
CID 159443131
N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclopropyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
CID 163770927
Bis(3-[2-[4-[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]acetyl]-5-cyclopropyl-1-(4-fluorophenyl)-6-isocyanopyridin-2-one);tert-butyl 4-[4-[6-amino-5-(4-amino-2-fluorophenyl)-3-pyridinyl]pyrazol-1-yl]piperidine-1-carboxylate;tert-butyl 4-[4-[6-amino-5-[4-[2-[5-cyclopropyl-1-(4-fluorophenyl)-6-isocyano-2-oxo-3-pyridinyl]-2-oxoethyl]-2-fluorophenyl]-3-pyridinyl]pyrazol-1-yl]piperidine-1-carboxylate;5-cyclopropyl-1-(4-fluorophenyl)-6-isocyano-2-oxopyridine-3-carboxylic acid
CID 163955861
N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclobutyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-(4-fluorophenyl)-4-oxo-1-propan-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-cyclobutyl-5-(4-fluorophenyl)-4-oxopyridine-3-carboxamide;N-[4-[2-amino-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-(4-fluorophenyl)-4-oxo-1-propan-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-2,5-difluorophenyl]-6-cyano-5-(4-fluorophenyl)-4-oxo-1-propan-2-ylpyridine-3-carboxamide
CID 163984900
CID 164971242
CID 164971242
(6R)-24-amino-14-cyclopropyl-9-fluoro-18-propan-2-yl-2,14,17,18,23-pentazapentacyclo[19.3.1.02,6.07,12.016,20]pentacosa-1(24),7(12),8,10,16,19,21(25),22-octaen-13-one;(6R)-24-amino-9-fluoro-14,19-dimethyl-18-propan-2-yl-2,14,17,18,23-pentazapentacyclo[19.3.1.02,6.07,12.016,20]pentacosa-1(24),7(12),8,10,16,19,21(25),22-octaen-13-one;(6R)-24-amino-9-fluoro-14-methyl-13-oxo-18-propan-2-yl-2,14,17,18,23,25-hexazapentacyclo[19.3.1.02,6.07,12.016,20]pentacosa-1(25),7(12),8,10,16,19,21,23-octaene-19-carbonitrile;(6R)-24-amino-9-fluoro-14-methyl-13-oxo-17-propan-2-yl-2,14,17,18,23-pentazapentacyclo[19.3.1.02,6.07,12.016,20]pentacosa-1(24),7(12),8,10,18,21(25),22-heptaene-19-carbonitrile;(6R)-24-amino-9-fluoro-14-methyl-13-oxo-18-propan-2-yl-2,14,17,18,23-pentazapentacyclo[19.3.1.02,6.07,12.016,20]pentacosa-1(24),7(12),8,10,16,19,21(25),22-octaene-19-carbonitrile
CID 167608763
(2S)-2-[[(2S)-2-(3-fluoro-4-methylphenyl)propyl]amino]-N-[5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-phenylacetamide;(2S)-2-[[(2R)-2-(3-fluoro-4-methylphenyl)propyl]amino]-N-[5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-phenylacetamide;bis((2R)-2-[2-(3-fluoro-4-methylphenyl)propylamino]-N-[5-(1-methylpyrazol-4-yl)-2-pyridinyl]-2-phenylacetamide);(2S)-2-[[(2R)-2-(4-methylphenyl)propyl]amino]-N-[5-[(3R)-3-methylpyrrolidin-1-yl]-2-pyridinyl]-2-phenylacetamide;(2R)-2-[2-(4-methylphenyl)propylamino]-N-[5-[(3R)-3-methylpyrrolidin-1-yl]-2-pyridinyl]-2-phenylacetamide
CID 167653394

Frequently Asked Questions

What is the IUPAC name of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
The IUPAC name of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide (CID 163929718) is N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide.
What is the SMILES notation for N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
The canonical SMILES for N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide is C=C(C)c1cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1C#N.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(Br)c(CNC)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.CCn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.Cn1cc(-c2cnc(N)c(-c3ccc(NC(=O)c4cc(C5CC5)c(C#N)n(-c5ccc(F)cc5)c4=O)cc3F)c2)cn1.N#Cc1c(C2CC2)cc(C(=O)Nc2ccc(-c3cc(-c4cnn(C5CCCCC5)c4)cnc3N)c(F)c2)c(=O)n1-c1ccc(F)cc1.
What is the InChIKey of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
The InChIKey is RHRACLVIPKURHC-UHFFFAOYSA-N. The full InChI is InChI=1S/2C36H31F2N7O2.C31H23F2N7O2.C30H26BrF2N7O2.C30H23F2N7O2/c37-24-8-11-27(12-9-24)45-33(17-39)29(21-6-7-21)16-31(36(45)47)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-4-2-1-3-5-26;1-21(2)29-16-31(36(47)45(33(29)17-39)27-11-8-24(37)9-12-27)35(46)43-25-10-13-28(32(38)15-25)30-14-22(18-41-34(30)40)23-19-42-44(20-23)26-6-4-3-5-7-26;1-39-16-19(15-37-39)18-10-25(29(35)36-14-18)23-9-6-21(11-27(23)33)38-30(41)26-12-24(17-2-3-17)28(13-34)40(31(26)42)22-7-4-20(32)5-8-22;1-3-39-16-18(14-37-39)17-10-23(28(34)36-13-17)22-9-6-20(11-26(22)33)38-29(41)24-12-25(31)27(15-35-2)40(30(24)42)21-7-4-19(32)5-8-21;1-3-38-16-19(15-36-38)18-11-24(28(34)35-14-18)23-9-6-21(12-26(23)32)37-29(40)25-10-17(2)27(13-33)39(30(25)41)22-7-4-20(31)5-8-22/h8-16,18-21,26H,1-7H2,(H2,40,41)(H,43,46);8-16,18-20,26H,1,3-7H2,2H3,(H2,40,41)(H,43,46);4-12,14-17H,2-3H2,1H3,(H2,35,36)(H,38,41);4-14,16,35H,3,15H2,1-2H3,(H2,34,36)(H,38,41);4-12,14-16H,3H2,1-2H3,(H2,34,35)(H,37,40).
What are the key properties of N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide?
N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide has a molecular weight of 3012.98 g/mol, XLogP of 30.03, 34 rotatable bonds, 11 hydrogen bond donors, and 40 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-cyclohexylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-2-oxo-5-prop-1-en-2-ylpyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-5-bromo-1-(4-fluorophenyl)-6-(methylaminomethyl)-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-ethylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-1-(4-fluorophenyl)-5-methyl-2-oxopyridine-3-carboxamide;N-[4-[2-amino-5-(1-methylpyrazol-4-yl)-3-pyridinyl]-3-fluorophenyl]-6-cyano-5-cyclopropyl-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide is sourced from PubChem (CID 163929718), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).