2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide

C₇₅H₉₀F₉N₁₅O₉ — CID 163988623

About 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide

2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide (PubChem CID 163988623) has the molecular formula C₇₅H₉₀F₉N₁₅O₉ and a molecular weight of 1516.62 g/mol. Its IUPAC name is 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide
• PubChem CID: 163988623
• Molecular Formula: C₇₅H₉₀F₉N₁₅O₉
• Molecular Weight: 1516.62 g/mol
• Exact Mass: 1515.69
• IUPAC Name: 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide
• SMILES: CC(O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F.C[C@@](O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F.C[C@](O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F
• InChI: InChI=1S/3C25H30F3N5O3/c3*1-23(35,25(26,27)28)18-6-5-17(21(29-18)33-11-9-24(7-8-24)10-12-33)22(34)31-19-3-2-4-20(30-19)32-13-15-36-16-14-32/h3*2-6,35H,7-16H2,1H3,(H,30,31,34)/t2*23-;/m10./s1
• InChIKey: TYOVMQJIPNLWHG-MIKFXDAHSA-N
• XLogP: 11.15
• TPSA: 272.46 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 21
• Rotatable Bonds: 15
• Heavy Atoms: 108
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1516.62
LogP ≤ 5	11.15
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	21

Frequently Asked Questions

What is the IUPAC name of 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide?

The IUPAC name of 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide (CID 163988623) is 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide.

What is the SMILES notation for 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide?

The canonical SMILES for 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide is CC(O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F.C[C@@](O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F.C[C@](O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F.

What is the InChIKey of 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide?

The InChIKey is TYOVMQJIPNLWHG-MIKFXDAHSA-N. The full InChI is InChI=1S/3C25H30F3N5O3/c3*1-23(35,25(26,27)28)18-6-5-17(21(29-18)33-11-9-24(7-8-24)10-12-33)22(34)31-19-3-2-4-20(30-19)32-13-15-36-16-14-32/h3*2-6,35H,7-16H2,1H3,(H,30,31,34)/t2*23-;/m10./s1.

What are the key properties of 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide?

2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide has a molecular weight of 1516.62 g/mol, XLogP of 11.15, 15 rotatable bonds, 6 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-(1,1,1-trifluoro-2-hydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-6-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridine-3-carboxamide is sourced from PubChem (CID 163988623), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).

Sources

• PubChem CID 163988623 — identifiers, structure, computed properties (public domain)

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