5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol

C65H82N22O3 — CID 164978917

IUPAC5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol
SMILESCN(c1ncc(-c2ncc(-c3cn[nH]c3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.Cc1cnc(Nc2cnc(-c3ccc(N4CCC[C@H](C(C)C)C4)nn3)c(O)c2)cn1.Cc1ncc(Nc2cnc(-c3ccc(N4CCCC(C(C)C)C4)nn3)c(O)c2)cn1
InChIInChI=1S/2C22H27N7O.C21H28N8O/c1-14(2)16-5-4-8-29(13-16)21-7-6-19(27-28-21)22-20(30)9-17(10-25-22)26-18-11-23-15(3)24-12-18;1-14(2)16-5-4-8-29(13-16)21-7-6-18(27-28-21)22-19(30)9-17(11-25-22)26-20-12-23-15(3)10-24-20;1-20(2)7-15(8-21(3,4)28-20)29(5)19-23-12-16(26-27-19)18-17(30)6-13(9-22-18)14-10-24-25-11-14/h6-7,9-12,14,16,26,30H,4-5,8,13H2,1-3H3;6-7,9-12,14,16,30H,4-5,8,13H2,1-3H3,(H,24,26);6,9-12,15,28,30H,7-8H2,1-5H3,(H,24,25)/t;16-;/m.0./s1
InChIKeyFEOTXCZPIHGFSQ-OWGVEZNLSA-N
MW1219.52 g/mol
LogP10.69
Rot. Bonds14

About 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol

5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol (PubChem CID 164978917) has the molecular formula C65H82N22O3 and a molecular weight of 1219.52 g/mol. Its IUPAC name is 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol.

Molecular Properties

Compound Name5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol
PubChem CID164978917
Molecular FormulaC65H82N22O3
Molecular Weight1219.52 g/mol
Exact Mass1218.69
IUPAC Name5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol
SMILESCN(c1ncc(-c2ncc(-c3cn[nH]c3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.Cc1cnc(Nc2cnc(-c3ccc(N4CCC[C@H](C(C)C)C4)nn3)c(O)c2)cn1.Cc1ncc(Nc2cnc(-c3ccc(N4CCCC(C(C)C)C4)nn3)c(O)c2)cn1
InChIInChI=1S/2C22H27N7O.C21H28N8O/c1-14(2)16-5-4-8-29(13-16)21-7-6-19(27-28-21)22-20(30)9-17(10-25-22)26-18-11-23-15(3)24-12-18;1-14(2)16-5-4-8-29(13-16)21-7-6-18(27-28-21)22-19(30)9-17(11-25-22)26-20-12-23-15(3)10-24-20;1-20(2)7-15(8-21(3,4)28-20)29(5)19-23-12-16(26-27-19)18-17(30)6-13(9-22-18)14-10-24-25-11-14/h6-7,9-12,14,16,26,30H,4-5,8,13H2,1-3H3;6-7,9-12,14,16,30H,4-5,8,13H2,1-3H3,(H,24,26);6,9-12,15,28,30H,7-8H2,1-5H3,(H,24,25)/t;16-;/m.0./s1
InChIKeyFEOTXCZPIHGFSQ-OWGVEZNLSA-N
XLogP10.69
TPSA315.64 Ų
H-Bond Donors7
H-Bond Acceptors24
Rotatable Bonds14
Heavy Atoms90
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001219.52
LogP ≤ 510.69
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1024

Analyze 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol with MolForge

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Related Compounds

2-[6-[(3R)-3-ethylpiperidin-1-yl]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol
CID 165053503
2-[6-[(3R,5S)-3,5-dimethylpiperazin-1-yl]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol
CID 155287118
2-[6-[(3S)-3-propan-2-ylpiperazin-1-yl]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol;dihydrochloride
CID 155287252
5-(1H-pyrazol-4-yl)-2-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]pyridin-3-ol
CID 155287326
2-[6-(3-methylpiperidin-1-yl)pyridazin-3-yl]-5-(pyridin-3-ylamino)pyridin-3-ol
CID 165040049
2-[6-[3-(tert-butylamino)pyrrolidin-1-yl]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)phenol
CID 167504154
5-(5-fluoropyrimidin-2-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol
CID 139536558
5-(1-methylimidazol-4-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol;hydrochloride
CID 155772539
2-[6-[(3R,4S)-3-fluoro-2,2,6,6-tetramethylpiperidin-4-yl]oxypyridazin-3-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol
CID 155287411
3-[3-hydroxy-4-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenyl]-1H-pyridazin-6-one;hydrochloride
CID 139536490
5-(6-methoxy-1,2,4-triazin-3-yl)-2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]phenol
CID 139536902
2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(5H-pyrrolo[2,3-b]pyrazin-2-yl)phenol
CID 139536580

Frequently Asked Questions

What is the IUPAC name of 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol?
The IUPAC name of 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol (CID 164978917) is 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol.
What is the SMILES notation for 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol?
The canonical SMILES for 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol is CN(c1ncc(-c2ncc(-c3cn[nH]c3)cc2O)nn1)C1CC(C)(C)NC(C)(C)C1.Cc1cnc(Nc2cnc(-c3ccc(N4CCC[C@H](C(C)C)C4)nn3)c(O)c2)cn1.Cc1ncc(Nc2cnc(-c3ccc(N4CCCC(C(C)C)C4)nn3)c(O)c2)cn1.
What is the InChIKey of 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol?
The InChIKey is FEOTXCZPIHGFSQ-OWGVEZNLSA-N. The full InChI is InChI=1S/2C22H27N7O.C21H28N8O/c1-14(2)16-5-4-8-29(13-16)21-7-6-19(27-28-21)22-20(30)9-17(10-25-22)26-18-11-23-15(3)24-12-18;1-14(2)16-5-4-8-29(13-16)21-7-6-18(27-28-21)22-19(30)9-17(11-25-22)26-20-12-23-15(3)10-24-20;1-20(2)7-15(8-21(3,4)28-20)29(5)19-23-12-16(26-27-19)18-17(30)6-13(9-22-18)14-10-24-25-11-14/h6-7,9-12,14,16,26,30H,4-5,8,13H2,1-3H3;6-7,9-12,14,16,30H,4-5,8,13H2,1-3H3,(H,24,26);6,9-12,15,28,30H,7-8H2,1-5H3,(H,24,25)/t;16-;/m.0./s1.
What are the key properties of 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol?
5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol has a molecular weight of 1219.52 g/mol, XLogP of 10.69, 14 rotatable bonds, 7 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[(5-methylpyrazin-2-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;5-[(2-methylpyrimidin-5-yl)amino]-2-[6-[(3R)-3-propan-2-ylpiperidin-1-yl]pyridazin-3-yl]pyridin-3-ol;2-[3-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,2,4-triazin-6-yl]-5-(1H-pyrazol-4-yl)pyridin-3-ol is sourced from PubChem (CID 164978917), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).