(3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine

C26H36ClN7 — CID 166735936

IUPAC(3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine
SMILESCc1cc(N2CCC3(CC[C@@H](C)C3N)CC2)n2c(CN(C)C)cnc2c1-c1ccnc(N)c1Cl
InChIInChI=1S/C26H36ClN7/c1-16-5-7-26(23(16)28)8-11-33(12-9-26)20-13-17(2)21(19-6-10-30-24(29)22(19)27)25-31-14-18(34(20)25)15-32(3)4/h6,10,13-14,16,23H,5,7-9,11-12,15,28H2,1-4H3,(H2,29,30)/t16-,23?/m1/s1
InChIKeyDPIQRDUGQAIEIM-ADRQNKRLSA-N
MW482.08 g/mol
LogP4.35
Rot. Bonds4

About (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine

(3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine (PubChem CID 166735936) has the molecular formula C26H36ClN7 and a molecular weight of 482.08 g/mol. Its IUPAC name is (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine.

Molecular Properties

Compound Name(3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine
PubChem CID166735936
Molecular FormulaC26H36ClN7
Molecular Weight482.08 g/mol
Exact Mass481.27
IUPAC Name(3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine
SMILESCc1cc(N2CCC3(CC[C@@H](C)C3N)CC2)n2c(CN(C)C)cnc2c1-c1ccnc(N)c1Cl
InChIInChI=1S/C26H36ClN7/c1-16-5-7-26(23(16)28)8-11-33(12-9-26)20-13-17(2)21(19-6-10-30-24(29)22(19)27)25-31-14-18(34(20)25)15-32(3)4/h6,10,13-14,16,23H,5,7-9,11-12,15,28H2,1-4H3,(H2,29,30)/t16-,23?/m1/s1
InChIKeyDPIQRDUGQAIEIM-ADRQNKRLSA-N
XLogP4.35
TPSA88.71 Ų
H-Bond Donors2
H-Bond Acceptors7
Rotatable Bonds4
Heavy Atoms34
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500482.08
LogP ≤ 54.35
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 107

Analyze (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine with MolForge

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Launch Full Analysis

Related Compounds

[8-(2-amino-3-chloro-4-pyridinyl)-5-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-7-methylimidazo[1,2-a]pyridin-3-yl]methanol
CID 164743522
(3S,4S)-8-[7-amino-8-(2-amino-3-chloro-4-pyridinyl)-3-(fluoromethyl)imidazo[1,2-a]pyridin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine
CID 164743701
4-[5-(4-amino-4-methylpiperidin-1-yl)-7-methylimidazo[1,2-a]pyridin-8-yl]-3-chloropyridin-2-amine
CID 164743690
5-(4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-8-(2,3-dichloro-4-pyridinyl)-3-(hydroxymethyl)imidazo[1,2-a]pyridine-7-carbonitrile
CID 164743880
(6S)-1'-[8-(2-amino-3-chloro-4-pyridinyl)-2,6,11-triazatricyclo[5.3.1.04,11]undeca-1,3,5,7,9-pentaen-3-yl]-2-[(dimethylamino)methyl]spiro[4,6-dihydrocyclopenta[d][1,3]thiazole-5,4'-piperidine]-6-amine
CID 167048036
4-[5-(4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-7-methyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl]-3,3-difluoro-1H-pyrrolo[2,3-b]pyridin-2-one
CID 164743566
8-[6-amino-5-[(2-amino-3-fluoro-4-pyridinyl)sulfanyl]pyrazin-2-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine
CID 167176008
(3S,4R)-8-[5-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]pyrazin-2-yl]-3-ethenyl-8-azaspiro[4.5]decan-4-amine
CID 135197189
8-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine
CID 164743638
[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-[(1S)-1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl]-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-2-[(dimethylamino)methyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-2-(fluoromethyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;(1S)-1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-3-(fluoromethyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
CID 165066873
8-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-[1,2,4]triazolo[1,5-a]pyrazin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine
CID 164743744
(3S,4S)-8-[8-(2,3-dichlorophenyl)sulfanyl-2-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine
CID 164743715

Frequently Asked Questions

What is the IUPAC name of (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine?
The IUPAC name of (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine (CID 166735936) is (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine.
What is the SMILES notation for (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine?
The canonical SMILES for (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine is Cc1cc(N2CCC3(CC[C@@H](C)C3N)CC2)n2c(CN(C)C)cnc2c1-c1ccnc(N)c1Cl.
What is the InChIKey of (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine?
The InChIKey is DPIQRDUGQAIEIM-ADRQNKRLSA-N. The full InChI is InChI=1S/C26H36ClN7/c1-16-5-7-26(23(16)28)8-11-33(12-9-26)20-13-17(2)21(19-6-10-30-24(29)22(19)27)25-31-14-18(34(20)25)15-32(3)4/h6,10,13-14,16,23H,5,7-9,11-12,15,28H2,1-4H3,(H2,29,30)/t16-,23?/m1/s1.
What are the key properties of (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine?
(3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine has a molecular weight of 482.08 g/mol, XLogP of 4.35, 4 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for (3R)-8-[8-(2-amino-3-chloro-4-pyridinyl)-3-[(dimethylamino)methyl]-7-methylimidazo[1,2-a]pyridin-5-yl]-3-methyl-8-azaspiro[4.5]decan-4-amine is sourced from PubChem (CID 166735936), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).